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Methods Analgesic effects of Shengning suppository were observed with pain model mice by acetic acid or hot plate test. Antiinflammatory effects were studied with ear acute edema model induced by dimethylbenzene in mice and rat foot edema model induced by carrageen, and antipruritic action was observed with allergic pruritic model caused by histamine in guinea pigs.

采用二甲苯所致的小鼠耳廓肿胀和角叉菜胶所致大鼠足跖肿胀炎症模型,热板法和扭体法及磷酸组织胺的致痒试验,观察参宁栓的抗炎、镇痛、止痒作用。

Methods:The anti-inflammatory effect was determined with the models of the swelling of mouse ear and the rat carrageenin paw edema.

1。抗炎作用:小鼠耳廓肿胀法和大鼠足跖肿胀法。2。

Methods:stimulating the animal model of rats with the experimental prostatitis by injecting carrageenin into rat prostates.We compared the model group with other groups which had taken Nanyanxiao granule,and made pathological examination of prostate.

采用向大鼠前列腺组织内注入角叉菜胶的方法复制大鼠前列腺炎模型,并分别对模型组及口服男炎消冲剂后的大鼠组进行前列腺组织病理学检查。

Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde i...

结果表明,天然牛黄,中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE2含量。

It could also suppress paw edema induced by carrageenin in rat and writhing induced by acetic acid in mice, but has no effect on the ear swelling caused by dimethylbenzene and cotton granulation hyperplasia and latent period of pain reaction in tail immersion test in mice.

对角叉菜胶致大鼠足肿胀和醋酸致小鼠扭体反应有一定的抑制作用,但对二甲苯致小鼠耳肿胀、小鼠棉球肉芽肿增生、小鼠温浴致痛反应潜伏期无明显影响。

Feeding of immune milk powder could inhibit odema of rat footpad induced by carrageenin and formaldehyde and the formation of accestoma of mice caused by cotton embedded hypophloeodally.

系统免疫并不增加乳中IgG含量,但IgG的抗体特异性大大增强;免疫乳中乳抗体对24种不同病原菌的凝集价为25-28,为普通乳中乳抗体凝集价的8-128倍。

Methods (1) The influence on the rats with non-bacterial prostatitis of 1.5% carrageenin. Rats were divided randomly into the normal control group, the model control group, the Qianliean low-dose group (1.5 g/kg), mid-dose group (3.0 g/kg), high-dose group (6.0 g/kg), with 10 rats in each group. All groups were treated continuously for 7 days, once a day. The model control group was given distilled water, 30mins after the last medication, injects 1.5% carrageenin 0.05ml in each rat's prostate, after 24hs, behead execute the rats and record the white blood cell number and Lecithin density.(2) the influence on the swelling ears of rats.

方法(1)对1.5%角叉菜胶致大鼠非细菌性前列腺炎的影响:将大鼠随机分为正常对照组、模型对照组、前列安颗粒小剂量组(1.5 g/kg)、前列安颗粒中剂量组(3.0 g/kg)、前列安颗粒大剂量组(6.0 g/kg)及阳性药前列舒乐颗粒组(2.4 g/kg)6组,每组10只,各给药组大鼠连续灌胃给药7日,每日1次,模型对照组给予等容量蒸馏水,末次给药后30 min,在每鼠前列腺内注入1.5%角叉菜胶0.05 mL,24 h后断头处死大鼠,取致炎前列腺组织,镜下记录白细胞数和卵磷脂小体密度。

Corton oil,inhibit the rat foot swelling induced by carrageenin,It could increase the mice pain threshold induced by hot plate and inhibit theobviously anti-inflammatory and analgesic effects.

可明显抑制巴豆油所致小鼠耳廓肿胀和角叉菜胶所致大鼠足跖肿胀,能明显提高热板法小鼠痛阈,对甲醛疼痛模型小鼠舔足反应

Results The decoction intragastric injection showed a marked suppressive effect on the normal and adranalectomized rat's hind paw oedema induced by carrageenin. In addition, at the dosage of 150g/kg, Smilax china ig reduced the content of PGE2 in inflammatiory tissue and the content of NO, MDA in serum, and the content of NO in inflammatory tissue at the dosage of 90, 150g/kg.

结果:拔葜灌胃给药能明显抑制角叉菜胶所致正常大鼠和去肾上腺大鼠足肿胀,150g/kg拔葜可降低肿胀足爪组织中PGE2及血清中NO、MDA含量,90、150g/kg拔葜可降低肿胀足爪组织中NO含量。

Pae (25-100mg/kg, ip) not only inhibited the swelling of mouse pinnea induced by xylene in a dose-dependant manner, but also suppressed the edema of rat hind paw induced by injection of 1% carrageenin at a higher dose (100 mg/kg, ip).

Pae(25-100mg/kg,ip)可剂量依赖性地抑制二甲苯所致的小鼠耳肿胀,高剂量(100mg/kg,ip)时可抑制角叉菜胶所致的大鼠足跖肿胀。

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