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ZGF can effectively inhibite the expression of PCNA and AFP in rat hepatic precancerous lesion tissue, and ZGF has the function of lessening the paraplasm of rat hepatic precancerous lesion tissue.

大剂量正肝方能有效降低大鼠癌前病变肝组织PCNA和AFP的表达,减轻大鼠癌前病变肝组织的异常增生。

A PE model in rat can be established successfully by cutting off the lower three couples of costal cartilages near the sternum bilaterally. The imitate Nuss procedure is safety performed on rat for pectus correction and a desired chest configuration can be obtained.

通过胸骨旁切断幼鼠下位三对肋软骨可成功的建立漏斗胸动物模型;动物仿Nuss手术的手术过程安全,矫形效果满意,&Z&字形钢针固定牢靠。

To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray. Of 2300 cDNA clones from low-abundance rat brain cDNA bank, 6 were identified as differentially expressed genes/ESTs in the hippocampus 35 days after lesion, in which none was confirmed by Northern blot. Of 8000 cDNA elements, custom cDNA array identified 47 as differentially expressed genes/ESTs with above 3-fold changes in the hippocampus 35 days after lesion, in which 25 were up-regulated and 22 down-regulated.

中文题名去传入海马的差异表达基因筛选和Cystatin C表达副题名外文题名 Screening of the differentially expressed genes and cystatin C expression in the deafferented hippocampus 论文作者应国新导师周长福研究员学科专业神经生物学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数121页关键词海马星型胶质细胞 Cystatin C 基因表达去神经海马馆藏号BSLW /2003 /Q42 /27 为了阐明中枢神经系统损伤后神经可塑性的分子机制,本实验探索了多种方法,包括传统差异筛库、传统cDNA array和cDNA microarray,对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。

Whole-cellpatch-clamp technology demonstrated that VDPG (1g/L) had notsignificant effects on the delayed-rectified K~+ current, TTX-sensitive Na~+ current and high-voltage-activated Ca~(2+) current of rat dorsalroot ganglion cells. The fast transiet K~+ current of cottonbollworm dorsal DUM cells, the fast transiet K~+ current, Na~+ current andhigh-voltage-activated Ca~(2+) current of Periplaneta Americana dorsalunpaired median cells were also not significantly affected byVDPG at the same concentration. However, VDPG had significant effecton the fast transiet K~+ current of Pieris rapae. The VES had not significanteffects on the high-voltage-activated and low-voltage-activated Ca~(2+)current of rat DRG cells.

膜片钳电生理实验显示1g/L毒囊粗毒对蜚蠊DUM神经元的快瞬时钾电流、钠电流、高电压激活的钙电流,对棉铃虫快瞬时钾电流和大鼠DRG细胞延迟整流钾电流、TTX-S型钠电流、高电压激活的钙电流均无明显作用,却对菜青虫快瞬时钾电流有明显作用;电刺激粗毒对大鼠DRG细胞低电压和高电压激活的钙通道无明显作用。

Research of ototoxicity of neomycin to rat vestibular hair cellObjective:To research neomycin ototoxicity for vestibule hair cell of rat, and provide the reference for the pharmacal vestibular dysfunction animal model developement.

本文对前庭功能障碍动物模型的建立、基因导入前庭的方法和Math1基因对药物损害后大鼠前庭感觉上皮毛细胞再生的作用等进行了研究。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp),说明莲子心酚性总碱对博莱霉素致大鼠肺纤维化有一定治疗作用,可能的作用机制:降低肺纤维时胶原含量;抑制肺成纤维细胞的增殖;抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

The aim is to use rat model of formalin result to pain to observe rat praxiology responses after giving ASA , The results found that: The rats showed spontaneous pain-related responses after formalin test. After being injected formalin into one hindpaw, the rats of F group immediately showed intense pain-related response: flinching / shaking and licking / biting injected paws.

在福尔马林炎性痛动物模型测定给药后大鼠的痛行为反应,发现ASA可以明显抑制F引起的双相痛反应,故从行为学的水平确定了ASA有显著的镇痛效应。

The data of RT-PCR also indicated that, in prepubertal rat (20-day-old) tissues, GLUT8 expression was comparatively much lower than that in the adult rat tissues.

RT-PCR数据还显示,在20d龄的青春前期大鼠的不成熟睾丸和心、肝、肾、脾等其它组织器官中,GLUT8基因表达水平相对于成年大鼠要低一些。

The Tongfuxingshen liquid proctoclysis can promote the patients in unconscious state to conscious state, and improve the degree of coma and the scores of nervous functional defects,To observe the expression of HSP70, HO-1mRNA and the Cerebral vessels permeability, encephaledema in rat brain after experimental haemorrhagic stroke. Hemorrhagic stroke Sprague Dawley rat model was made by injecting collagenase type Ⅶ and hepathrom stereotaxically, Rats were randomly divided into fake operation group, model group and enema group, take orally group, in three time point (3 days, 5 days, 7 days) we observed the change of cerebral vessels permeability, encephaledema and HSP70 immunohistochemistry, HO-1mRNA hybridization in situ.

结果表明,通腑醒神液直肠滴注较灌胃起效快,能尽快促使昏迷患者神志清醒,意识清醒时间平均为4.94天,而灌胃组为6.9天,经统计学处理有极显著性差异;明显改善患者的昏迷程度,第8天治疗组Glasgow-Pittsburgh昏迷评分值平均为29.39分,对照组为26.60分,经统计学处理有极显著性差异;治疗后14天临床疗效比较,通腑醒神液直肠滴注组总显效为54.84%,总有效率为80.65%,而灌胃组总显效为43.33%,总有效率为66.67%,经统计学处理无差异性,可能为样本量过少有关,尚需进一步增加样本量评估。

In situ hybridization using biotinylated POMC cRNA probe made it possible to localize POMC mRNA in the rat ovary. POMC mRNA predominantly existed in corpora lutea of diesturs, pregnant and pseudopregnant rat ovaries. POMC containing cells scattered in the ovarian intertitium were seen. The amount of POMC mRNA in granulosa cells was negligible.

采用生物素标记的POMCcRNA作为探针,进行原位杂文,研究POMCmRNA在大鼠卵巢中的分布,实验表明,POMCmRNA主要分布于间期,妊娠和假孕大鼠卵巢黄体中,间质细胞也可见少量POMCmRNA,而卵泡颗粒细胞中POMCmRNA极少。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力