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Chapterl Establishment of the chronic and pressure-induced SD rat models for acoustic neurinomas Object To establish the chronic and pressure-induced SD rat models of acoustic neurinomas for the purpose of further experimental research on acoustic neurinoma related electrophysiology, function and pathomorphology of facial nerves and cochlear nerves.

第一章 SD大鼠听神经瘤慢性压力模型的建立目的建立SD大鼠听神经瘤慢性压力模型,为听神经瘤所致面、听神经电生理、功能及病理学改变的研究奠定基础。

This part is to explore the effect of rhEPO on neuromotor function,secondary pathology change and expression of Caspase-3, which was peritoneal injected at different time after rat traumatic spinal cord injury Method Wistar rat were randomized into normal group,sham operation group, blank control group and rhEPO group.

第二部分脊髓损伤后促红细胞生成素对Caspase-3表达的影响目的:半胱氨酸蛋白酶被认为是细胞凋亡过程中最重要的一系列蛋白酶,其中Caspase-3是最重要的蛋白酶,是多种凋亡途径的共同下游效应部分。

Objective: To elucidate the role HSP27 during amelogenesis and odontogenesis in the teeth of limited growth by analyzing its expression in enamel organ of developing rat molar teeth and rat molar.

目的:通过分析大鼠磨牙及其发育过程中,Hsp27 在成釉器中的表达,阐明Hsp27 在牙釉质、牙本质形成中的作用。

Objective To investigate the interrelationship between the expression of VEGF and the oncosis of neuron after ICH by establishing the rat ICH model through the expression of oncosis of neuron after ICH and the cell location of VEGF-positive cells in perihematoma and the expression of VEGF. Methods The rat ICH model was induced by two-step.

目的 通过建立大鼠脑出血动物模型观察血管内皮生长因子在出血灶周的细胞定位和动态表达变化和脑出血后神经细胞胀亡时程表达以探讨两者之间的相关性。

The method of PCR-analyzed microsatellites can be used for distinguishing between inbred and outbred、different strains、strain and substrain.and it provides a lot of information for genetic mapping,gene location and heredity probe of the inbred rat strains,and a speedy、convenient method for genetic research of the inbred rat.

因此,本实验为开展近交系大鼠遗传作图、基因定位和为实验动物的遗传背景监测提供可靠的信息,为大鼠遗传基因的研究提供了一个快捷简便、特异准确的方法。

ZGF can effectively inhibite the expression of PCNA and AFP in rat hepatic precancerous lesion tissue, and ZGF has the function of lessening the paraplasm of rat hepatic precancerous lesion tissue.

大剂量正肝方能有效降低大鼠癌前病变肝组织PCNA和AFP的表达,减轻大鼠癌前病变肝组织的异常增生。

A PE model in rat can be established successfully by cutting off the lower three couples of costal cartilages near the sternum bilaterally. The imitate Nuss procedure is safety performed on rat for pectus correction and a desired chest configuration can be obtained.

通过胸骨旁切断幼鼠下位三对肋软骨可成功的建立漏斗胸动物模型;动物仿Nuss手术的手术过程安全,矫形效果满意,&Z&字形钢针固定牢靠。

To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray. Of 2300 cDNA clones from low-abundance rat brain cDNA bank, 6 were identified as differentially expressed genes/ESTs in the hippocampus 35 days after lesion, in which none was confirmed by Northern blot. Of 8000 cDNA elements, custom cDNA array identified 47 as differentially expressed genes/ESTs with above 3-fold changes in the hippocampus 35 days after lesion, in which 25 were up-regulated and 22 down-regulated.

中文题名去传入海马的差异表达基因筛选和Cystatin C表达副题名外文题名 Screening of the differentially expressed genes and cystatin C expression in the deafferented hippocampus 论文作者应国新导师周长福研究员学科专业神经生物学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数121页关键词海马星型胶质细胞 Cystatin C 基因表达去神经海马馆藏号BSLW /2003 /Q42 /27 为了阐明中枢神经系统损伤后神经可塑性的分子机制,本实验探索了多种方法,包括传统差异筛库、传统cDNA array和cDNA microarray,对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。

Whole-cellpatch-clamp technology demonstrated that VDPG (1g/L) had notsignificant effects on the delayed-rectified K~+ current, TTX-sensitive Na~+ current and high-voltage-activated Ca~(2+) current of rat dorsalroot ganglion cells. The fast transiet K~+ current of cottonbollworm dorsal DUM cells, the fast transiet K~+ current, Na~+ current andhigh-voltage-activated Ca~(2+) current of Periplaneta Americana dorsalunpaired median cells were also not significantly affected byVDPG at the same concentration. However, VDPG had significant effecton the fast transiet K~+ current of Pieris rapae. The VES had not significanteffects on the high-voltage-activated and low-voltage-activated Ca~(2+)current of rat DRG cells.

膜片钳电生理实验显示1g/L毒囊粗毒对蜚蠊DUM神经元的快瞬时钾电流、钠电流、高电压激活的钙电流,对棉铃虫快瞬时钾电流和大鼠DRG细胞延迟整流钾电流、TTX-S型钠电流、高电压激活的钙电流均无明显作用,却对菜青虫快瞬时钾电流有明显作用;电刺激粗毒对大鼠DRG细胞低电压和高电压激活的钙通道无明显作用。

Research of ototoxicity of neomycin to rat vestibular hair cellObjective:To research neomycin ototoxicity for vestibule hair cell of rat, and provide the reference for the pharmacal vestibular dysfunction animal model developement.

本文对前庭功能障碍动物模型的建立、基因导入前庭的方法和Math1基因对药物损害后大鼠前庭感觉上皮毛细胞再生的作用等进行了研究。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力