查询词典 rat gall

The SAP rat model induced by 5% sodium deoxycholate retrogradely common biliopancreatic ducts injection via duodenum puncturing was first reported by Aho HJ, and it was regarded the most classical SAP animal model which was widely adopted by SAP researcher in the world.

研究背景目前SAP的发病机制和病理生理特点尚未完全明了，虽然通过近30年国内外专家和临床科研的实践，SAP在治疗的思想和策略上取得了一定的进展，但总的临床死亡率仍旧高达20～30%，预后不良，因此对SAP的研究目前仍然是外科临床科研的热点之一。

Rat in Group B was set an air bladder which was empty and not perfused water. Water of 0.6 ml, 0.8 ml, 1.0 ml, 1.2 ml, 1.4 ml and 1.5 ml was perfused respectively into the air bladders which were set in the colon of rats in group C, D, E, F, G and H. Then the changes of ethology of the rats were recorded in interval of an hour.

应用疼痛行为学的观察方法，观察1h各组动物的行为学改变，并采用免疫荧光化学的方法，观察大鼠DCN中神经元被激活的标志c-fos及胶质细胞的胶质原纤维酸性蛋白(glial fibrillary acidic protein， GFAP)和小胶质细胞特异性补体OX42的表达情况，空白对照组是在疼痛高峰点(1.2 ml)处死取材。

In this study, the severe acute pancreatitis specific EN formula was composed based on the rationale of the nutritional mechanism of the disease, and the alanyl- glutminedipeptide was added into the formula. This study was cut in the combining site of clinical nutrition pharmacology and immunology to probe the effect of Gln in the special formula in SAP rat form several aspects including mucous barrier, immunological barrier and systemic inflammatory responses.

本课题研究在成功建立急性重症胰腺炎模型的基础上，在SAP专用肠内营养配方中加入水溶性和稳定性好的丙-谷氨酰二肽，并从临床营养药理学和免疫学的结合点切入，采用免疫学、分子生物学研究手段，重点从肠屏障功能、免疫功能、细胞因子方面研究早期肠内营养加谷氨酰胺防治SAP营养治疗作用机制。

Purpose To study the mechanism of effects of aldose reductase inhibitors on rat mesangial cells in vitro proliferation induced by PDGF-BB.

目的 探讨醛糖还原酶抑制剂影响血小板源性生长因子－BB促体外培养大鼠系膜细胞增殖作用的机制。

To evaluate the effect of aldosterone on connective tissue growth factor mRNA expression in cultured rat mesangial cells.

目的 探讨醛固酮对大鼠肾小球系膜细胞结缔组织生长因子基因表达的影响。

Objective To explore the possibility of aldosterone biosynthesis and expression of aldosterone receptor in rat mesangial ceils in vitro.

目的 探讨培养的大鼠肾小球系膜细胞能够自身合成分泌醛固酮及存在醛固酮受体的可能性。

Objective: To investigate the effects of matrine on the proliferation of rat cardiac fibroblasts induced by aldosterone , and to research the mechanism of regression of heart fibrosis.

目的：研究苦参碱对醛固酮诱导大鼠心肌成纤维细胞增殖的影响，探讨其抑制心肌纤维化的机制。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，"PMN-EC"相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Objective To evaluate the possible role of alkaloid sinomenineon chronic rejection in rat heart transplantation model.

目的 探讨青藤碱对大鼠心脏移植慢性排斥反应抑制作用的可能机制。

Objective To compare on affection between cryotherapy and immunosuppressive agent for alloˉgraft of rat sciatic nerve.

目的 探讨应用冷冻法与免疫抑制剂法对同种异体鼠坐骨神经再生效果的比较。

A carrier gas such as nitrogen is directed through line 20 and valve 22 to connect with line 26 and mix with the gas sample.

如氮气之类的载体通过管线20和阀22引入，与管线26相通，与气体样品混合。

But for the most part, knaves and parasites had the command of his fortune

然而支配他的家产的大多是恶棍和寄生虫。