查询词典 ras

Results The DNA was obtained from PPJ through a nasopancreatic tube. Aberrant p16 methylation and K- ras gene mutation were detected in the same samples of PPJ. Sensitivity,specificity,positive predictive values,negative predictive values and accuracy of HE staining for pancreatic cancer were 40%,100%,100%,45.4% and 60.0%,respectively. Of the 20 cases of pancreatic cancer,K- ras gene mutation was detected in 14 (70%) and the p16 gene was shown to be methylated in 7 (35%). Of the 8 cases of chronic pancreatitis,K-ras gene mutation was detected in 2 (25%). Of the 2 cases of mucinous cystoadenoma of pancreas,K-ras gene mutation was detected in 1 (50%). Aberrant methylation of p16 was not detected in pancreatic juice samples from patients with chronic pancreatitis and mucinous cystoadenoma of pancreas.

结果 所有胰液标本均成功抽提出DNA，30例胰腺疾病病人胰液标本同时进行了K-ras基因突变和p16基因启动子区5′CpG岛甲基化检测，其中20例胰腺癌病人胰液中K-ras基因突变率为70%（14/20），p16基因甲基化率为35%（7/20），8例慢性胰腺炎中K-ras基因突变率为25%（2/8），2例胰腺囊腺瘤病人中K-ras基因突变率为50%（1/2），慢性胰腺炎和胰腺囊腺瘤病人胰液中无p16基因甲基化。

Result:22 out of 40(55%) primary tumors were detected the point mutations in the coden 12th of k-ras an d n-ras,h-ras.The point mutations of p53 E5 and E7 were found in 16 laryng eal tumors (16/40,40%).

结果：H-ras基因突变9例，突变率为22 。5%(9/40)；K-ras基因突变8例，突变率为20%(8/40)，N-ras基因突变5例，突变率为12.5%(5/40)。p53基因第5外显子突变7例，突变率为17.5%(7/40)；第7外显子突变9例，突变率为22 。5%(9/40)。5例发现有两种基因突变，且均表现为ras基因和p53外显子改变。

Objective To investigate the point mutation of codon 12 of H-ras and K-ras in tissues of gastric carcinoma.

目的 探讨人胃癌组织中H-ras、K-ras基因第12密码子点突变情况及意义。

AIM: To detect the expressions of HER-2/neu (c-erbB-2) and Ras oncogenes in cervical carcinoma,and to evaluate the roles of HER-2/neu and Ras in the genesis and development of cervix squamous cell carcinoma and adenocarci- noma.

目的研究HER-2/neu(c-erbB-2)和Ras癌基因在宫颈腺癌和鳞癌中的表达及意义，探讨其在宫颈癌发生发展中的作用。

The RhoA oncogene , have been revealed in recent years, are closely related to various malignant tumours. RhoA, belonging to Rho family, is one member of the ras superfamily, whose encoding production, namely RhoA protein, pertaining to micromolecular mass GTP conjugated protein family, in GTP conjunctive active form and GDP conjunctive unreactive form. It exist in the latter form in normal cells and the switch of the two forms enables them to educe functions, paralleling"molecular switch", the diminutive G protein in activated state being able to activate the wink dromo-iter to work functions, which is in the resemblance of process during which the Ras genic mutation induces its continous activations.

RhoA是近年来新发现的与多种恶性肿瘤密切相关的癌基因，RhoA属于Rho亚家族，是ras基因超家族的一员，其编码产物RhoA蛋白属于小分子量GTP结合蛋白族，分为GTP结合的活性型和GDP结合的非活性型两类，在正常细胞内以GDP结合的非活性型存在，两种活性形式之间的转换使他们能够发挥一种类似"分子开关"的作用，活性态的小G蛋白能激活下游的信号传导通路，行使其功能。

The mutation of K-ras gene and the abnormal transcription of FHIT gene have close correlatetion with tumorigenic development of lung cancer.K-ras and FH1T became the molecule target of smoke cancerigenic.

K-ras、FHIT基因异常与肺癌发生密切相关。

In vitro, K-ras mutation ASODN could apparently inhibit the growth of Patu 8988 cells （ in a certain degree of dose-dependent and time-dependent manner）,induce apoptosis and decrease the expression of K-ms protein and K-ras mRNA in contrast with SODN, RODN and control groups.

针对K-ras基因第12密码子点突变的反义寡核苷酸可明显抑制人胰腺癌Patu 8988细胞生长，促进细胞凋亡，其机制可能是通过下调K-ras蛋白和K—ras mRNA表达而起作用。

And the memory operating frequency, as well as there are three options related to: CAS Latency, RAS to CAS Delay and RAS Precharge Time.

与内存的工作频率以及相关的有三个选项：CAS Latency、RAS to CAS Delay和RAS Precharge Time。

Our results suggest that coden 12 of the H-ras oncogene may be a specific target for the mutagenic activation by tobacco smoke, and smoking is an important factor in the induction of H-ras oncogene mutation.

提示H-ras基因可能是被烟草激活的一个特殊位点，吸烟是导致H-ras基因突变的重要因素。

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RS，RAS牌摩托车专用链条，以多年制造链条的丰富经验，且不断努力研究发展和严格的质量管理，利用最先进的自动化机械设备所生产之链条具有在高速运转下所表现出的高强度，耐磨损，耐冲击，耐疲劳的高级品质。

The circulation, consumption and reproduction of the trilogy have not only testified to its historical significance and literariness, but also invested it with new meanings.

该三部曲的流通、消费与再生产不仅验证了其历史意义及文学性，而切还赋予它以新的意义。

If he thought that he could buy me off, he would be wrong.

如果他认为他可以收买我，那他就大错特错了。