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Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

After two years in Fez, CRC sailed for Spain, carrying with him many treasures, among them rare plants and animals accumulated during his wanderings.

经过两年在非斯来，华润航行西班牙，与他进行太多的珍宝，其中珍稀植物，并在其漫游积累的动物。

It is a rare complication of fibroid disease.

是纤维样肌瘤的一种非常少见的并发症。

Chondromyxoid fibroma is a rare benign bone tumor. The etiology of chondromyxoid fibroma is still unknown.

软骨粘液纤维瘤是一种罕见的良性骨瘤，它发生的原因至今仍不明。

Congenital-infantile fibrosarcoma is a rare tumor with which clinicians should be familiar.

先天性幼儿纤维瘤是一罕见而且值得特别注意的肿瘤。

ABSTRACT The anisotropy bonded NdFeB is a hotspot in the field of rare earth permanent magnet at present.

各向异性粘结NdFeB是目前稀土永磁研究的一个热点。

In some countries, blood sports like bull fighting and cock fighting are common and hunting rare animals for commercial purposes has brought about an even more serious problem in the protection of the ecosystem.

在一些国家，血腥的运动比如斗牛和斗鸡非常普通并且为了商业目的狩猎稀有动物已经带来了更严重的生态系统保护的问题

In the mausoleum compound, there is an imposing tablet pavilion and the straight divine road lined with 18 pairs of huge and vivid stone statues of figure and animals,which are considered rare masterpieces of ancient sculpture.

在陵墓大院，有一个凉亭，并实行片神圣的直路一条一八双和生动的巨大石像的人物，动物，认为这是难得的古代雕塑杰作。

What's more, visible were bright but extremely rare filamentary striae from the comet's expansive dust tail.

更有甚的是，人们还能看到由彗尾展开的明亮但又极度罕见的丝状细纹。

Influence of trace rare earth additives such as Ce, Y and Gd on microstructure and properties of Cu-Ag in situ filamentary composite was studied in this paper.

作者： 张晓辉1，闫琳1，宁远涛2单位： 1。北京有色金属研究总院有研亿金新材料股份有限公司，北京 100088；2。昆明贵金属研究所，云南昆明 650221

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。