查询词典 quercetin

Quercetin(3,5,7,3",4"-pentahydroxyflavone) is a kind of effective component from natural druggery, which has many pharmacological actions such as anti-flammatory, antiviral and antioxidation.

槲皮素(quercetin， 3，5，7， 3"，4"五羟基黄酮)有抗炎、抗病毒、抗氧化等多种药理作用，但其抗氧化活性较弱。

Compare with other flavonoid the inhibition effect of Luteolin is better than Quercetin and Genistein.

并且与其他类黄酮化合物比较Luteolin的抑制效果更胜於大众所熟知的抗氧化、抗癌物质物质Quercetin、Genistein。

Objective To study the effects of quercetin on proliferation of rat glioma C6 cell line in vitro.

目的：研究类黄酮化合物槲皮素（quercetin，QUE）对体外培养的大鼠脑胶质瘤C6细胞增殖调控的作用。

The results showed that the phenolics in cranberry would reduced. The free quercetin showed the best stability. And the flavonoids and proanthocyanidins were the second. The total phenolics showed the worst stability.

结果显示，蔓越莓中的酚类化合物含量会随储存时间而下降，其中以游离态quercetin之安定性最佳，总类黄酮及前花青素则其次，在总酚类化合物之安定性最差。

Their chemical structures were characterizd on the basis of spectral and chemical evidences to be: Sarracenin (1), 2-methyl-5-hydroxy-7-O-ethyl caffeate chromome (2), Naringenin(3), 2-methyl-5, 7-dihydroxychromome (4), 2-methyl-6-hydroxyl-cinnamic acid methyl ester (5), eriodictyol (6), quercetin (7), Naringenin-7-O-β-D-glucoside( 8 ), eriodictyol-7-O-α-D-glucoside (9), quercetin-3-O-β-D-glucoside(10). In addition, one compound was abtained from the n-butanol frationk, which was finally identified as Morrosiside(11) by spectral and chemical evidences.

以波谱数据及其理化性质鉴定为：Sarracenin(1)，2-甲基-5-羟基-7-O-咖啡酸乙酯色原酮(2)，柚皮素(3)，2-甲基-5，7-二羟基色原酮(4)，2-甲基-6-羟基苯丙烯酸甲酯(5)，圣草酚(6)，槲皮素(7)，柚皮素-7-O-β-D-葡萄糖苷(Naringenin-7-O-β-D-glucoside)(8)，圣草酚-7-O-α-D-葡萄糖苷(eriodictyol-7-O-α-D-glucoside)(9)，槲皮素-3-O-β-D-葡萄糖苷(quercetin--3-O-β-D-glucoside)(10)；另外从正丁醇萃取部位分离得到1个化合物，以波谱数据和文献对照鉴定为：Morroniside(11)。

In o rder to explore the relationship bet ween HSP70and P-g p,the human hepatocarc inoma line HepG2cells was induced by heat shock in vitro,and the inhibiting effect of quercetin on them was obs erved at the same time to seek the method incre asing the effectiveness of hyperthermal therapy on hepatocarcinoma.

本研究拟通过热休克诱导人肝癌HepG2细胞表达HSP70和P-gp，并观察槲皮素(quercetin，Qu)对二者表达的抑制效应。

Quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E wereisolated from the flower of Acanthopanax senticosus. Searching bioactive natural compound and establishing quality evaluation standard arefocused on this experiment. Using cold immersing of 70% methanol to extract from flower ofAcanthopanax senticosus and integrating macroporous resin, silica gel column chromatography,sephadex gel to abstract. We obtained five monomer compounds (compoundⅠ-compoundⅤ),quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E. That five compoundswere determined by HPLC in eight parts of Acanthopanax senticosus (flower, root, leaf fruit,shoot, new shoot, phloem of shoot, skin of shoot), which provide science bases for establishingquality evaluation system and settle infarctate foundation.

本文以从刺五加花蕾中寻找具有重要生物活性的天然化合物和建立质量评价标准为主要目的，对其化学成分进行研究，采用70％甲醇冷浸的方法对刺五加花蕾中的成分进行提取，运用大孔树脂吸附色谱法、硅胶柱层析法以及葡聚糖凝胶柱层析相结合的方法进行分离，得到5种单体化合物，分别为槲皮素、槲皮素鼠李糖苷、金丝桃苷、紫丁香苷和刺五加苷E；利用高效液相色谱法对这5种化合物在刺五加花蕾中的含量进行了测定；考察了8个部位(花蕾、根、叶、果、茎干、新枝、茎韧皮部、茎皮)中这5种化合物的含量分布情况，并作一比较，为今后建立刺五加质量评价体系提供了科学依据，奠定了坚实的基础。

Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

In this study, we determined that the antimutagenic properties of various tea extracts including green, oolong, pu-erh tea, and black tea and six polyphenols include rutin, quercetin, apigenin, gallic acid, umbelliferone, and tannic acid were examined by Ames test which is a widely applied short-term bacterial assay for detecting DNA damage effect of mutagen.

在本篇研究中，我们探讨利用Ames test的方法筛检不同品种茶类包括绿茶、乌龙茶、普洱茶、红茶和数种常见的多酚类化合物包括单宁酸tannic acid、gallic acid、rutin、umbelliferone、apigenin、quercetin对於抑制PhIP（2-amino-1-methyl-6-phenylimidazo(4，5-b)pyridine）和 2-AAF（2-Acetylaminofluorene）两种致突变剂的抗突变作用。

But both 20 years and 2 years old of pu-erh tea extracts show a strong inhibitory effects against 2-AAF. In addition, tannic acid, gallic acid, rutin, umbelliferone, and quercetin exhibited stronger antimutagenicities against PhIP than apigenin; while all of these polyphenols displayed inhibitory effect against 2-AAF.

而比较数种多酚类化合物发现，tannic acid、gallic acid、rutin、umbelliferone和quercetin对於抑制PhIP的抗突变作用比apigenin来的有效，但是apigenin和其他多酚类化合物对於抑制2-AAF的抗突变作用则均具有明显的抑制效果。

I'll try to bring the conversation around to the subject of money.

我想把谈话引到钱的问题上。

Only from a superior source of goats can an exceptional chevon product be made.

羊源 有优良的羊源才能生产出好品质的羊肉。