查询词典 pyknotic

After HIFU irradiation, the histopathological changes of lesions of liver and kidney mainly characterized as completely coagulative necrosis, cell debris, pyknotic nuclei.

HIFU损伤后，肝脏和肾脏治疗区的组织病理变化主要表现为细胞的完全性坏死，细胞结构完全破坏，胞浆均质状，细胞核变形、碎裂、固缩、溶解。

In electricity plus thermal group, the pathologic alterations were slighter than model group; there was little crack on the surface of cartilage, with intact collagen fiber structure and less pyknotic chondrocytes. Although some chondrocytes shrank, there were intact cell organs in many chondrocytes even chondrocyte cluster in some regions.

疏密波+热软膜组在病理程度上的改变明显轻于模型对照组，软骨表面裂纹少，胶原纤维结构基本完整，固缩的软骨细胞少，虽可见部分退变的软骨细胞，但部分软骨细胞具有较多的细胞器，某些区域形成软骨细胞簇。

Results:Expression of CD3、CD4 in stimulated PBLs was about 10 percent more than those eithout stimulation Nucleus pyknotic、border gathering and collapse were found in hepatoma cell, which showed typical apoptosis.

结果：CD3、CD4分子表达高于刺激前约10%，肝癌细胞出现凋亡，细胞核固缩、边聚、裂解。

Histopathological observation: 4 weeks after operation, diffuse presence of empty lacunae and pyknotic nuclei of osteocytes were found in the trabeculae, and few newborn micrangium could been seen in group A; lots of empty lacunae and a small quantity of newborn micrangium could been found in group B; and large amounts of osteoblats and newborn micrangium were found around the necrosis regions in groups C and D.

组织病理学观察，术后4周A组见空骨陷窝，无新生毛细血管；B组空骨陷窝较多，有少量新生毛细血管：C、D组空骨陷窝减少，坏死区有大量增生活跃的成骨细胞及新生毛细血管。D组空骨陷窝阳性数及微血管密度分别为19.30 1.52和7.08 1.09，与其他组比较差异有统计学意义（P〈0.05）。

Results In comparison with the controls, the nuclei of many neurons were pyknotic or disappeared, the Nissl substance also showed various degrees of abnormality, and the dendrites were stretched in the high-fluoride and low-iodine groups, and in the high-fluoride plus low-iodine group, espacially in the early developmental stage.

结果 与对照组相比，高氟组和低碘组大鼠大脑皮质及海马内有较多神经元核固缩、核溶解及细胞轮廓不清晰。

Results The nucleus morphology of the hepatocytes was abnormal ,the nucleus was pyknotic, the mitochondria crista was broken. The endoplasmic reticulum was reduced and swelled.

结果：实验组肝细胞核形态异常、固缩，线粒体脊断裂，内质网减少且肿胀，毛细胆管扩张，内有胆泥淤积。

Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

After treatment with AT9810,the cell became smallerand condensed,typical signs,such as cytoplasmicconcentration,chromatin agglutination,pyknotic necleus,necleus cleavage,apoptosis corpuscle,was found inmorphological observation.

经AT9810处理后的细胞体积变小皱缩，形态学观察具有典型凋亡细胞的特征：胞浆浓缩，染色质凝集，核固缩、裂解及凋亡小体形成。

MSG could insult the functions and structures of specific brain areas of adult mice through blood-brain barrier. The ability of discrimination learning in Y-maze was affected markedly, especially in 4. 0g/kg MSG group, meanwhile, dark pyknotic and loss of neurons were shown in arcuate nucleus of hypothalamus, but not in hippocampus. Consistent changes occured in mitochondrial membrane protein bound 〓 by 〓-fluoresent probe, i.

MSG可以透过成年小鼠血脑屏障产生神经毒性作用。4.0g/kg MSG对小鼠空间分辨学习能力的损伤程度较2.5g/kg MSG更为明显，同时下丘脑弓状核神经元出现核固缩及神经元数目明显减少，相同处理未引起海马神经元的明显变化。

Light microscope inspection in MAN, DXM and BC groups showed lesse ned brain edema, slight increase of perivascular space, and occasional nerve ce ll pyknotic nucleus.

MAN，DXM，BC组脑组织水肿程度较B E组减轻，仅见少量的血管周围间隙增宽，偶有神经细胞核固缩，DXM组无神经细胞空泡样变性。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷