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Bioinformatics studies of the functional impact of alternative splicing have revealed a wide range of regulatory mechanisms, from NAGNAG sites that add a single amino acid; to short peptide segments that can play surprisingly complex roles in switching protein conformation and function (as in the Piccolo C2A domain); to events that entirely remove a specific protein interaction domain or membrane anchoring domain.

选择性剪切的功能性影响的生物信息学研究揭示了各式各样的调控机制，从添加一个单氨基酸的NAGNAG位点；到可以在开关蛋白质构象和功能(如在Piccolo C2A区域)中起到惊人地复杂作用的短肽片段；到完全移除一个特定蛋白质相互作用区域或膜锚定区域的事件。

The reporter understands, the domain name of the athlete of many projects Olympic Games such as football of 、 of fire of badminton 、 of gymnastic 、 of 、 of weight lifting of 、 of natant 、 diving here second present list inside, thered is no lack of to attend San so like Huang Xu among them the domain name Huangxu.cn of the Olympic Games champion of the " of founding member of " San day that the Olympic Games has taken card of gold of two Ge Olympic Games, guo of Chen Relin 、 of 、 of Wang Xin of Chen Yibing 、 jumps green 、 of Chen Yan of bright 、 of the domain name Liuzige.cn that also included the champion of new advance Olympic Games such as Liu Zi song and fire of Wu Minxia 、、 Wang Feng.

记者了解到，游泳、跳水、举重、体操、羽毛球、射击、足球等多个项目奥运运动员的域名都在此次捐赠名单内，其中不乏像黄旭这样参加了三届奥运会拿过两个奥运金牌的&三朝元老&的奥运冠军的域名huangxu.cn，也包括了刘子歌等新晋奥运冠军的域名liuzige.cn及吴敏霞、火亮、陈艳青、陈一冰、王鑫、陈若琳、郭跃、王峰、金紫薇、庞伟、邹凯、唐宾等奥运冠军域名。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

PhyA is the photoreceptor of far-red light perception in Arabidopsis and mediates the inhibition of the hypocotyl elongation under FR light. phyA has two domains : the N-terminal photosensory domain with a chromophore-binding site and the C-terminal domain which contains signaling motifs such as a kinase domain.

phyA为阿拉伯芥中远红光的接受体，在远红光中可抑制下胚轴延长，phyA的N端带有一个可感受光讯息的色基，C端含有可传递讯息给下游基因的kinase区域。

The chromatin unfolding assay showed that ,like the wild-type transactivation domain, two variants that represent benign polymorphisms did not induce chromatin unfolding or only induced subtle change. Contrary to the behaviors of the wild type and two benign variants, four cancer-predisposing mutations in the transactivation domain superactivate the chromatin unfolding. The results suggest that the chromatin unfolding assay can aid in the characterization of deleterious mutations in the C-terminal transactivation domain of BRCA1 and may provide more reliable presymptomatic risk assessment.

对这些重组质粒的染色质伸展活性检测表明，野生型pwt和两种良性多态性突变体不具有染色质伸展活性或只有极微弱的染色质伸展活性，而其他4种乳腺癌易感突变体均具有过强的染色质伸展活性，提示利用染色质伸展技术可预测BRCA1转录激活区基因型与乳腺癌发生风险的表现型的关系。

Objective: Mannose-binding lectin is a plasma protein belonging to the family of collectins, composed of a N-terminal segment, helical coiled-coil hinge region, collagen-like stalk domain., and globular type C lectin domain or carbohydrate recognition domain. Full MBL biological function requires assembly to at least the tetrameric level.

目的：甘露聚糖结合凝集素(Mannose-binding lectin， MBL)是属于C型凝集素家庭胶原凝集素的一种血清蛋白，包括N末端区（N-terminal segment）、螺旋铰链区（helical coiled-coil hinge region）、胶原样区（collagen-like region，CRL）及球形C型凝集素区或糖识别区（carbohydrate recognition domain ，CRD）等4部分结构区域，四个亚单位的MBL形成有功能的多聚体。

Based on the analysis of bistatic SAR geometry model, bistatic SAR echoed signal is modeled in the double range variables domain in this paper, and the relationship between the double range variable domain and the single range variable domain is established. Then a range-dependent Doppler algorithm for imaging processing airborne bistatic SAR raw data of the translationally invariant configuration is derived, and the effect of error of the algorithm is analyzed by simulating.

摘要该文通过对机载双基地SAR非移变几何模型的分析，建立了双距离变量域的回波信号模型，由于回波数据是在距离和域，该文推导了距离和变量与双距离变量的转换关系，解决了该模型向距离和变量域转换的问题；提出了适用于非移变模式的变多普勒参数的双基地RD算法，并对该算法中引入变多普勒斜率所存在的误差进行了仿真分析。

Suppose that, on the assumption that we have such background theories on the table, we have specified the domain and counter-domain, and specified our access to the counter-domain as unproblematic.

假设：在预设'我们拥有关于桌子的这样的背景理论'下，我们拥有指定的区域和反区域，指定了对反区域的可达。

Firstly, after getting predicted multiples, we use adaptive subtraction algorithm to eliminate multiples and get some inverse wavelets corresponding to every trace in one shot gather, then construct inverse wavelets domain by those inverse wavelets. Secondly, use median filtering method to get inverse wavelet estimation in inverse domain. Thirdly, correct the misshaped inverse wavelets in inverse domain by the inverse wavelet estimation.

其步骤为：首先用SRMA方法预测出表面多次波，并对每一单炮进行单道自适应相减，得到逆子波，形成逆子波域；其次，在逆子波域采用中值滤波，提取接近真实逆子波的逆子波估计；第三，在逆子波域用逆子波估计对畸变的逆子波进行校正；最后采用校正后的逆子波来衰减多次波。

Aiming at the limitation of single-domain authentication provided by Direct Anonymous Attestation, a dynamic trust-based cross-domain authentication mechanism of DAA is proposed, which quantizes trust relation to trust value between 0 and 1, realizes cross-domain authentication by comparing trust value with expectation value.

针对直接匿名认证方案只提供单域认证的局限性，提出一种基于动态信任值的DAA跨域认证机制，通过将信任关系量化为[0，1]之间的信任值，并对域间信任值与信任阈值进行比较来实现可信平台模块用户的跨域访问。

I condoled with her in her loss.

我对她的损失表示同情

We have to admit the fact that the quality of life is as important as life itself.

我们必须承认这一事实：生命的质量和生命本身一样重要。