查询词典 proteins

The invention provides cytokine fusion proteins with an increased therapeutic index, and methods to increase the therapeutic index of such fusion proteins.

本发明提供了治疗指数增加的细胞因子融合蛋白和增加这些融合蛋白的治疗指数的方法。

The results showed that about610 protein spots could be visualized on the two dimensional electrophoresis map bycoomassie brilliant blue staining within Mr 9.0～100.0kD and pH 4～7,and about 94 spotswere differential expressed between male-sterile line and its maintainer line by PDQuestsoftware.Among those differential proteins,about 49 spots and 40 spots were differentialexpressed between uninucleate anther stage and binucleate stage respectively;Meanwhilecomparing with the 2-DE maps of the total proteins from the binucleate anther stage anduninucleate stage,15 differential spots were detectable at male-sterile line;and 16 differentialspots were detectable at its maintainer line.

在分子量9.0～100.0 kD、等电点4～7线性范围内，可识别约610个蛋白质点，PDQuest软件分析结果表明：在单核期不育系和保持系之间存在40个差异蛋白质点，二核期两者共有49个差异点；不育系在单核期和二核期两者之间存在有15个差异点，保持系在两个不同时期有16个差异点；不育系与保持系间在表达量上的差异蛋白质点以及不育系与保持系间特异表达或特异缺失的蛋白质点很可能与小麦雄性不育有关。3。

Cardiac hypertrophy is one of adaptive responses of the heart to a variety of pathological stimuli, including hypertension, myocardial infarction, congenital heart disease, heart valvula disease, and perturbations in sarcomeric function due to altered expression or mutations of contractile proteins. Increase in wall tension and hormonal stimuli are thought to directly activate various membrane-bound receptors and signal transduction cascade within cardiomyocytes resulting in the activation of immediate early genes and responsive genes such as c-jun, c-fos, c-myc, egr-1, ANF, BNP. Then the expression of construction proteins such as MLC-1, skeletal α-actin was unregulated.

中文题名hhlim基因的表达调节及其与心肌细胞肥大发生之间的关系副题名外文题名 hhlim gene expression regulation and its role in development of cardiomyocyte hypertrophy 论文作者郑斌导师温进坤韩梅学科专业生物化学与分子生物学研究领域\研究方向学位级别博士学位授予单位河北医科大学学位授予日期2003 论文页码总数106页关键词心肌细胞肥大基因表达心肌肥厚 hhlim基因馆藏号BSLW /2003 /R542.2 /33 心肌细胞肥大是高血压、心脏瓣膜病、急性心肌梗塞及先天性心脏病等临床常见疾病的一种并发症，是心肌细胞对多种病理刺激的一种适应性反应。

The result shows that these;proteins showed some similarity with known proteins in the database. They may have function in the resistance responses to Verticillium wilt.

对这三个点进行质谱分析，再进行数据库查询，结果找到了与之具有同源性的蛋白质，分析可能与抗病反应有关。

Results of Western-blot reveal: along with the increase concentration of taxol, the expressions of Fas、FasL proteins increased gradually, while the expressions of Caspase-8、Caspase-3 zymogen proteins decreased gradually.

Western-blot结果显示：随着紫杉醇浓度的增加，Fas、FasL蛋白表达量逐渐增加，Caspase-8、Caspase-3酶原蛋白表达量逐渐减少。

The recoveries for 2,3-BD and acetoin were 91%and 92%,respectively.Aqueous two-phase extraction of 2,3-BD from real fermentation broth,the removal ratio of cells was above 99%,and the soluble proteins were about 85%in the top phase,which resulted in easy recovery of 2,3-BD from the top phase by vaporization because a viscous slurry was not formed by glucose,cells and soluble proteins at high temperature as in traditional separation methods.In addition,the cells recovered from the fermentation broth could be used as inoculum for further fermentation.

结果表明，目标产物2，3-丁二醇和乙偶姻主要富集在上相中，而葡萄糖主要富集在下相中；当异丙醇和硫酸铵的质量浓度分别是34%和20%时，2，3-丁二醇和乙偶姻的分配系数分别为8.29和8.98，回收率分别达到91%和92%；采用该条件对发酵液直接进行萃取，细胞的去除率在99%以上，可溶性蛋白去除率可达85%。

Results 37 unique proteins increased remarkably more than 2 folders up while 8 proteins decreased more than 2 folders down in breast adenofibroma tissue than in normal breast tissue.

所获得的图谱经DeCyder软件分析。结果：在乳腺纤维瘤病的病变组织中，有37个蛋白质表达水平显著增加，另外8个蛋白质表达水平显著下降。

Objective To study the differentially expressed proteins between mature and antral follicles and identify the proteins crucial for follicle development and oocyte fertilization.

目的 应用蛋白质芯片和质谱技术，建立人成熟卵泡液及窦卵泡液的蛋白质表达指纹图谱，寻找在卵泡生长发育过程中起关键作用的蛋白质。

Results In comparison with those in the antral follicular fluid, the concentration of 4 proteins were significantly different in mature follicular fluid, including two up-regulated and two down-regulated proteins.

结果 成熟卵泡液组与窦卵泡液组蛋白质谱相比，有4种蛋白质在含量上有显著差异，2种蛋白质在成熟卵泡液组表达上调，2种蛋白质表达下降。

Leukocyte proteins concentrations were determined with Bradford Method. Phosphoproteins in the collected leukocyte proteins were enriched by BDTM Phosphoprotein Enrichment Kit. Finally the enriched phosphoproteins were separated by SDS-PAGE and dyed by argentation, and the electrophoresis map of SDS-PAGE was analyzed by Scion Image Tool.

刺激组加入表皮生长因子(40 μg/L)；抑制剂组加入细胞外信号调节激酶特异性抑止剂UO126 （10 μg/L）和表皮生长因子（ 40 μg/L）；对照组加入等量的培养基，用Bradford法测定细胞蛋白质含量，BDTM Phophoprotein Enrichment Kit分离富集白细胞磷酸化蛋白质，SDS-PAGE分离磷酸化蛋白质，银染法染色，采用Scion Image软件分析电泳结果。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。