查询词典 propositus

The 46 T/T polymorphism of F12 gene might be the cause of FⅫ:C deficiency for the propositus.

F12基因的46 T/T多态性可能是导致先证者FⅫ缺乏的原因。

The genomic DNA was extracted from the peripheral blood of the 16-year-old propositus, female.

突变位点经限制性内切酶分析证实。108名健康献血者作对照。

The propositus of? thalassemia were tested with two steps of screening technique.

地中海贫血先证者筛查按两步筛选方案进行。

Of six members in this family screened for this type of HPFH deletion,four were positive.Prenatal diagnosis of the fetus showed the same results as that of the propositus.

在此基础上，我们对该家庭的中间型地贫高风险胎儿进行了产前基因诊断，结果显示胎儿的基因型与先证者完全相同，为HPFH和β地贫双重杂合子，故建议终止妊娠。

Four kinds of mutation: CD8,CD8/9,CDs41/42 and IVS-Ⅰ-5 were revealed at the gene identification of 10 propositus of β-thalassemia.

其中的HbJ Tashikuergan［α19(AB1)Ala→Glu］系世界首次报道，CD8和CDs8/9为在中国人中首次发现。

The electrophoresis of the hemolysate of the propositus at pH 8.6 revealed that the abnormal hemoglobin was slow-moving and its mobility was similar to that of the G group.

先证者的溶血液在pH8.6电泳中出现泳速相当于Hb G组的慢速血红蛋白区带。肽链分析证实此异常血红蛋白为α链异常。

Study of a trait or disease begins with the affected person （the proband, propositus , proposita , or index case）.

对某一特征或疾病的研究要从患者开始。

Study of a trait or disease begi with the affected person （the proband, propositus , proposita , or index case）.

对某一特征或疾病的研究要从患者开始。

The relationship between the genetic deficiencies and hemorrhagic disorder were characterized. The homozygosity of the Thr359Met in the propositus with FⅦ: C activity 2% was related to severe clinical symptoms; The proband with double heterozygous lesions of Arg152Leu and one single nucleotide deletion at position 11487-9, combined with Arg304Trp in exon 8 with FⅦ activity 1% suffered severe clinical bleeding tendency. one proband with double heterozygous mutations (Agr304Trp and Arg304Gln) with 10% of FⅦ activities characterized asymptom. the heterozygous mutations (Thr359Met, Arg152Gln,-55C→T) with FⅦ: C 1%～5. 5% showed moderate or mild clinical symptoms.

其中8961 G＞T（Arg152Leu）和10966-8delC两种突变为国际首次报道，IFSla+5g＞a突变导致的异常剪接为国际首次报道。1个F7及F10基因联合缺陷家系，其中，F10基因28139 G＞T（Val384Phe）突变为国际首次报道；发现了1个由F7及组织因子(tissue factor，TF)两种基因联合缺陷导致的出血家系，其突变分别为F7基因启动子区-55C＞T杂合突变；TF 9363 C＞T（Arg131Trp）杂合多态性（频率2.63％）。6种F7基因突变发生在催化区；2种突变发生在裂解位点；1种发生在启动子区；1种突变发生在剪接位点，除一种缺失突变外，其余均为点突变；所有家系的基因突变都来自先证者的父亲和/或母亲。

I think people in this lifetime in a rebirth.

我觉得人在这一生里其实也在轮回。

He had to tie her hands together.

他不得不把她的双手绑在一起。