查询词典 pronuclei

Here we show that transfer of pronuclei between abnormally fertilized human zygotes results in minimal carry-over of donor zygote mtDNA and is compatible with onward development to the blastocyst stage in vitro.

供体合子mtDNA的转移是很少的，所以该方法有可能防止mtDNA疾病在人类中的传播。

Methods:The HBVtransgenic mice were prepared by microinjection of complate 2.0 copy HBV genome into pronuclei fertilized eggs.

应用受精卵原核显微注射的方法，产生HBV转基因小鼠。

Offspring of the fertilized eggs whose pronuclei were injected of the plasmid were screened for transgene expression.

接著此载体以显微注射递送到小鼠受精卵中，其子代以聚合脢链锁反应筛选转殖基因是否嵌入其基因体。

Superovulated C57BL/6J female mice were sacrificed at 0.5 dpc and injected purified BAC into male pronuclei.

将由超排卵作用受精后0.5天的C57B/6J母鼠牺牲，并注射纯化后的重组MLL基因至精核中。

These data suggest that histone acetylation during nuclearremodeling (from the start of activation to the formation of pronuclei) is independent fromthe event that oocyte cytoplasm inhibits the transcription of specific genes in thedifferentiated cells, but induces reprogramming of gene expression.

这表明组蛋白的乙酰化修饰可能没有参与卵细胞质对分化细胞特有的基因转录的抑制，但引起了基因表达模式的变化。

Then, the two recombinant genes were microinjected into the male pronuclei of fertillized mouse eggs for generating transgenic mice harbouring the introduced genes, respectively.

进而将它们分别导入小鼠受精卵雄原核，作成相应的转基因小鼠，则发现它们都失去了表达特性。

PKC isoform was typically concentrated around the condensed chromosomes before the MI stage, but localized in the pronuclei of zygotes and the nuclei of blastomeres of early embryos.

PKC亚形集中在MI期前浓缩的染色体周围，也位于受精卵原核或早期胚胎分裂球的核。

RESULTS: FISH demonstrated that the male pronuclei in some one-cell embryos and the each nucleus in some two-cell embryos presented positive signals.

结果： 在单细胞胚和二细胞胚间期核内发现HBV DNA阳性杂交信号，RT-PCR可以扩增出HBx基因的特异条带，免疫荧光也可见到HBsAg阳性信号。

The results suggest: 1 during the transition of gametes to zygotes, the activation of the embryonic genome appeared relatively indiscriminate; It＇s reasoned to be due to the histone-protamine exchange occurred in male pronuclei and the dramatic changes in the chromosome structure happened during the first run of embryonic DNA replication, which caused the inappropriate and un-selectively ie.

在配子到合子的转变过程中，胚胎基因的激活可能是一个相对无序的、随机的过程。

Early cleavage rate,embryo quality,the rate of blastocyst,implantation and pregnant rates from these zygotes were observed,and the transferred embryos were selected according to the pronuclei orientation and early cleavage time.

根据受精卵原核构型的不同分为四组，结合构型类型及早期卵裂与否进行选择性移植，通过观察优质胚胎率、囊胚形成率、种植率和怀孕率，来评估合子原核构型和早期卵裂与胚胎发育潜力的关系。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。