查询词典 promoter

The transcriptional activities of survivin promoter in various cel1s were determined by detection of the expression of luciferase.

survivin启动子在前列腺癌细胞中具有较强启动活性，有可能成为新的前列腺癌靶向性基因治疗工具。

Through detecting the activity of luciferase, the effect of curcumin on the promoter of PSA was studied.

用免疫印迹Western-blotting技术检测雄激素受体的表达。

Next,we transfected the HOXD13 expression vector,luciferase reporter driven by EPHA7 promoter and renilla luciferase reporter into mouse C3H10T1/2 cell. Thirty six hours after transfection,relative luciferase activity was tested by luminometer.

结果显示，与野生型HOXD13蛋白相比，p.Q317R突变体对EPHA7启动子的转录激活作用明显降低，下降至野生型的13%，而p.1314L突变体对EPHA7启动子的转录激活作用也降低，但降低程度没有p.Q317R明显，为野生型的63%。

DJ McGinley succumbed to dark horse contender Markus Juva, the Finnish player completing a break and run for an 11-10 win interrupted by promoter Barry Behrman's customary 9 PM announcements and subsequent patriotic ceremony.

麦克金尼的DJ屈服于黑马竞争者马库斯juva ，芬兰选手完成一项突破和运行为1 11月10日赢得中断启动巴里behrman的习惯晚上九时，公告和随后的爱国仪式。

And, the methylation in promoter is differential between the two alleles in metaphase.

此外，启动子区的甲基化状态在中期也确有差异。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

They also had the opposite effect from methylated cytosines found in promoter regions.

而在基因的启动子区域里它们的影响和甲基胞核嘧啶正相反。

Objective: To investigate the methylation of p16 gene promoter in patients with breast cancer tissue.

目的：探讨乳腺癌组织中p16基因启动子区域的甲基化状态。

Objective To investigate the methylation of Id4 gene promoter in patients with chronic leukemia.

目的 探讨Id4基因在慢性白血病患者中的甲基化情况。

Objective To investigate the expression and promoter methylation of TIG2 genes in non - small cell lung cancer.

文章摘要：目的探讨TIG2基因在原发性非小细胞肺癌中的表达及意义。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。