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PartⅡThe mechanism elucidation about effects ofα-(2,3)/(2,6)sialic acid on the Cx43gap-junction functions.(1) Westernblotting experiment showed that the decrease of sialic acid didn\'t changethe Cx43 expression and its phospholation level.(2) Westernblotting experiment showed sialidase didn,t change the ZO-1 expression,IP and confocal experiment showed sialidase improved the interaction of Cx43 andZO-1.(3) Westernblotting experiment showed sialidase didn\'t change N-cadherin expression,IP and confocal experiment showed sialidase promoted the complex formation ofCx43 and N-Cadherin.(4)Sialidase could increase the ERK1/2 phospholation level,and enchanedintercellular homotypic adhesion,Immunofluorometric assay showed sialidase couldpromote the N-cadherin cluster on the membrance.

第二部分:α—(2,3)/(2,6)唾液酸对肿瘤细胞CX43间隙连接功能影响的机制研究1、Westernblotting结果表明降低细胞膜表面唾液酸并不改变Cx43的表达及其磷酸化水平:但Cx43连接斑形成增多;2、Westernblotting结果表明唾液酸酶作用后细胞ZO—1表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与ZO-1的结合;3、Westernblotting结果表明唾液酸酶作用后细胞N-cadherin表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与N-Cadherin复合物的形成;4、唾液酸酶作用后细胞内ERK1/2磷酸化水平明显增加,细胞间同质粘附增加,以及免疫荧光表明唾液酸降低后可促进N-cadherin的膜成簇。

Sugared drinks and fatty burgers were promoted by well-rewarded athletes whose own diets were carefully balanced for fitness and health. The administrators, even the ones who ran second in their elections, were comforted with first-class air travel, five-star hotels, generous expenses, honoraria and pensions all paid for by the big corporations.

体育组织的官员们,甚至那些在选举中败北的,都可以坐上头等舱的飞机,住上五星级的酒店,拿着高额的工资,还有那些大公司给他们提供的优厚的退休金,这使他们感到很舒服。

The young man promoted the new products hoppingly for more compensation.

这个年轻人卖力地促销新产品为的是能得到更多的奖金。

Tumor invasion was promoted by secretion of hydrolytic enzymes and degradation of tissue barrier.

肿瘤细胞通过分泌蛋白水解酶破坏周围的间质组织,促进肿瘤的浸润。

TNF-α at 103u/ml also promoted basal cAMP production from hyperfunctioning thyroid cells, but there was no effect at the level of 10-3-10u/ml.

TNF-α在10~(-3)~10U/ml的剂量范围内,对甲亢甲状腺细胞基础cAMP的生成无明显影响,但10~3U/ml的TNF-α则显著促进甲亢甲状腺细胞产生cAMP。

The data indicate, the hypernormal development of higher education of Jiangsu was mainly promoted by the development of the university under the province, catch educational resource is it keep the balance or slightly increase basically to supply in the course of developing educational capital source except that the government puts one's back into and the undertaking charge, the bank loan has played an important role.

江苏是我国的经济大省,也是教育大省,在高等教育超常规发展的大潮中,江苏高等教育的发展备受瞩目。本文就江苏高等教育发展的现状和未来发展作一分析与探讨。

The addition reactions with phosphine anion andthe CsF promoted Strecker reactions were chose to evaluate the relationship of thesetwo chiral groups in the diastereoselective additions of the imino group.

通过亚磷酸负离子的加成反应和CsF促进下的Strecker反应研究了这两个手性基团的不对称诱导的匹配情况。

A type of novel dis-substituted α-arylglycine derivatives was synthesized in high yields and high regioselectivity via the stepwise Friedel-Crafts reaction of phenols with N-tosyl imino ester promoted by TiCl〓.

发现在Mg/MeOH/超声波条件下,能高产率的得到N-Tos裂解后N-Boc保护的α-芳香甘氨酸衍生物,实现了一条简单、实用的合成N-Boc保护的α-芳香甘氨酸衍生物的方法。

Based on the "inlook" exhibition, we have promoted an "outlook" exhibition especially for young female artists.

基于&内力&展的英文主题 INLOOK ,我们在&内力&展的内部,推出一个对仗工整的& OUTLOOK &年轻女性艺术家特别项目。

Because war appeared as the opportunity to get promoted inofficial ranks and to earn fortune, historical events thuswere examined playfully,and scholars would suddenly be turnedinto medal-winning

由于战争作为获得功名富贵的机遇而发生,历史性事件因而被游戏化。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力