查询词典 proliferative

HOXB4,as a member of homeobox gene family is closely related to the self-renewal and proliferative ability of primitive

同源盒基因家族成员HOXB4 反映原始造血干/祖细胞的自我更新和增殖能力。

1 The expression of Bax began in the late proliferative phase, the highest level in the involuting phase.

TGFβ1在增生期血管瘤组织中表达较弱，阳性表达率43.75%，退化期血管瘤组织中表达强，阳性表达率83.33%，两组比较有显著性差异，p＜0.01。

Methods: The specimens were taken from 30 proliferative hemangiomas, 22 involuting hemangiomas,27 vascular malformations and 5 samples of normal skin.

皮肤血管瘤是婴幼儿较常见的一种良性血管增生性肿瘤，其增生、消退机制至今不明。

The expressions of Bax and TGFβ1 in 50 children cases of dermal hemangioma which were in proliferative phase or in involuting phase were detected by HE staining and immunohistochemical method. We also analysized the difference between the different phases of hemangioma , and try to find out the role of Bax and TGFβ1 in hemangiomatous proliferation and regression .

采用HE染色和免疫组织化学方法检测50例小儿皮肤血管瘤增生期、退化期Bax、TGFβ1的表达水平，并分析它们在不同时期血管瘤中的差别，近而探讨Bax、TGFβ1在血管瘤增生、消退中的作用。

Our study shows that Bax ,the protein of accelerating apoptosis, may participate in the proliferation and regression of hemangioma. 2 The expression of TGFβ1 in the involuting phase was higher than in the proliferative phase, the difference was statistically significant, p＜0.01. 3 This shows that Bax and TGFβ1 may be the important factors which cause the apoptosis of hemangioma and accelerate its regression as well.

1 Bax在血管瘤增生晚期开始表达，至退化期Bax的表达达到高峰，提示Bax这种促进细胞凋亡的蛋白参与血管瘤的增生与退化过程。2 TGFβ1在血管瘤退化期的表达高于增生期，差异有统计学意义，p＜0.01.3 提示Bax与TGFβ1可能是引起血管瘤凋亡，进而促进其退化的重要因素。

The expression of IGF-IR in the difference stages (proliferative stage and involuting stage) of hemangiomas was measured using SP immunohistochemical method and RT-PCR, comparing with vascular malformation and normal skin tissues at same time.

采用免疫组化SP法和半定量RT-PCR法检测不同分期血管瘤中IGF-IR的表达水平，并与血管畸形及正常皮肤标本进行比较。

Result: 1 HE staining 2 immunohistochemical method:①the positive expressive rate of Bax in proliferative phase and involuting phase of hemangioma, normal skin tissues in turn were

结果 1 HE染色：增生期血管瘤组织中可见条索状或片状内皮细胞增生，其间有不规则的内皮间隙和完整的血管腔，内皮细胞核肥大而淡染。

It is suggested that CDK2 might progress the proliferation of endothelial cells in human proliferative hernangiomas; while p27(superscript Kip1) might inhibit the proliferation of endothelial cells in involuting hemangiomas.

p27(上标 kip1)能抑制血管瘤内皮细胞的增殖，在血管瘤的退化过程中起了重要作用；而CDK2能促进血管瘤内皮细胞增殖，在血管瘤的增生过程中起了重要作用。

and materials:By immunohistochemistrical method, the expression of VEGF, c-myc and P53 were respectively observed in the tissue sections of 22 proliferative hemangiomas,23 involuting hemangi- omas and 16 vascular malformations.

材料和方法用免疫组织化学SP法检测22例增生期及23例消退期血管瘤及16例血管畸形组织中VEGF、c-myc及 P53蛋白的表达。

objective:to investigate the expression and significance of rb in the occurrence, development and regression of infantile hemangiomas.methods:the expression of rb was examined in the proliferative stage and catagen of human hemangiomas and normal skin tissues by using immunohistochemical technique.immunohistochemical technique for factorⅷ-related antigen was used to prove that the cells which expressed rb were endothelium.image analysis system was applied to measure the expression level of rb at different stages of hemangiomas and in normal skin tissues.results:the expression of rb was significantly lower in proliferating hemangiomas than that in involuting hemangomas(p.05).conclusion:rb might play an important role in the regression of human hemangioma endothelial cells and anti-angiogenesis.

目的：探讨rb蛋白在血管瘤发生、发展及退化过程中的表达状况及其意义。方法：采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中rb的表达水平，并结合第ⅷ因子相关抗原的免疫组织化学染色证实表达rb的细胞是血管内皮细胞。利用计算机图像分析技术测量不同时期血管瘤组织和正常皮肤组织rb表达的积分光密度和面积。结果：增生期血管瘤内皮细胞rb表达水平低于退化期，差异有显著性（p.05），退化期血管瘤内皮细胞rb表达水平与正常皮肤组织相比，差异有显著性（p.05）。结论：rb通过抑制血管瘤内皮细胞增殖和血管生成而在血管瘤的退化过程中起重要作用。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失