查询词典 proenzyme

In the pathogenesis and development of liver fibrosis, MMP-3 proenzyme protein expression level increased gradually, with the expression rate being maximum at an intermediate stage of fibrosis. And it decreased gradually during the late liver fibrosis and at thestage of liver cirrhosis, but remained relatively high levels above normal.

在肝纤维化发生发展过程中MMP - 3酶原蛋白表达水平逐渐增强，至肝纤维化中期到达最高峰，到肝纤维化晚期及肝硬化阶段其表达较中期下降，但仍高于正常对照水平。

Marked changes of apoptosis including condensation of chromatin and nuclear fragmentation were observed very clearly by Hoechst 33258 fluorescence staining and a characteristic "ladder" of DNA fragments was elicited by agarose gel electrophoresis; Western blot analysis revealed that caspase-3 was activated by the loss of caspase-3 proenzyme (32kDa) and the appearance of its 20kDa subunit, and that along with the apoptotic process caspase-3 activity was increased concurrently.

Hoechst 33258荧光染色观察到典型的核浓缩、核碎裂等细胞凋亡的形态学变化，琼脂糖凝胶电泳观察到细胞凋亡时的DNA"梯形"条带；Western blot检测结果表明32kDa的caspase-3酶原被激活，出现20kDa的亚单位活化片段，同时在细胞凋亡过程中，caspase-3活性显著增高。

Sequence analysis showed that the full-length cDNA sequence of Sc-SAMDC (GenBank Accession number: GQ246459) was 1 968 bp, with three open reading frames, tiny ORF, upstream ORF and main ORF. The mORF was 1200 bp encoding 399 amino acid residues with a molecular mass of 43.6 kD, and the deduced protein had two highly conserved function domains (proenzyme cleavage site and PEST domain).

序列分析显示，甘蔗Sc-SAMDC基因(GenBank Accession number： GQ246459) cDNA全长1968 bp，存在3个读码框（袖珍读码框tORF、上游读码框uORF和主读码框mORF），mORF长1200 bp，编码399个氨基酸的SAMDC酶原，预测分子量为43.6 kD，该酶原含有两个高度保守的功能结构域（酶原剪切位点和PEST结构域）。

In 5 μM. pseudolaric acid B-treated HeLa cells, caspase-3 proenzyme decreased followed by the degradation of caspase-3 substrates, ICAD (inhibitor of caspase dependent DNase) and PARP poly-(ADP-ribose polymerase.

土槿皮乙酸5μM作用于HeLa细胞后，caspase-3的酶原被降解，caspase-3底物ICAD(inhibitor of caspase activated DNase)和PARPpoly-(ADP-ribosepolymerase降解，caspase-3的抑制剂可部分抑制土槿皮乙酸诱导的细胞死亡，表明土槿皮乙酸诱导HeLa细胞凋亡时激活了caspase-3。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。