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A series of cholesterol-bearing O-carboxylmethyl chitosan conjugates with different degrees of substitution of the cholesterol moieties and cholesterol-bearing chitosan were synthesized by the succinyl linkages and characterized by Fourier transform infrared, Proton Nuclear Magnetic Resonance (~1H NMR) and elemental analysis. These hydrophobized chitosan derivatives were amphiphilic in nature and their self-aggregation behavior in aqueous media was evaluated by the fluorescence probe technique.

课题的主要研究内容如下:采用化学的方法合成了不同分子结构、不同取代度的系列胆甾醇基壳聚糖衍生物—胆甾醇基壳聚糖和胆甾醇基-羧甲基壳聚糖,并应用先进的分析手段电位滴定、红外光谱法(IR、核磁共振波谱法等对原料、中间产物以及产物进行了结构表征,衍生物分子中的胆甾醇基取代度(3.2%~12.5%)采用元素分析的方法进行检测。

These two series of probes differ in their mechanism of action. The first series exploits the concept of suicide substrate. When the probe is hydrolyzed by the target sulfatase, it will release an intermediate that undergoes elimination to form a reactive quinone methide which in turn reacts with nearby nucleophiles. The second series belongs to an electrophilic reagent which utilizes a cyclic sulfamate moiety serving both as the recognition unit and the trapping device.

这二系列标示分子的主要差异在於其标示机制,第一系列是源自於自杀性受质的概念,利用水解后的中间体会生成高反应性的quinone methide,来达到标示的效果;第二系列则是属於亲核性试剂型,采用环状胺基磺酸衍生物做为辨识端及捕捉机制,预期在其进入酵素的受质结合区后能与酵素催化中心形成共价键结。

This suggests that SPA-PAMAM-Au nanocomposites could be used as supersensitive optical probe for bioanalyses and medical diagnoses.

SPA-PAMAM-Au纳米复合物粒子可望广泛用作生物分析和医学诊断高灵敏度光学探针。

Influenced by Western Surrealistic poetics,Taiwan's Epoch Poetry Club probe into the world of subconsciousness and dreams.

受西方超现实主义诗学影响,台湾创世纪诗社对潜意识与梦的世界进行了深度的探索。

This text passes and analyses network technology characteristic and the general demand for campus network at present and practical application, it accords with systematic model of campus network of the network application demand in the campus at present to probe into, have used "top-down design philosophy " in networking, have discussed that tightens mode, all netted modes, some netted structure modes, the third layer of network technologies of exchanging the mode, wait a moment to three swapper, division and some key equipment and development of application system of VLAN odd key technology problems go on research.

本文通过分析网络技术特点和目前校园网的普遍需求及实际应用,探讨符合目前校园网络应用需求的校园网系统模型,在网络建设中运用了"自顶向下"的设计思想,讨论了紧缩模式、全网状模式、部分网状结构模式、第三层交换模式的网络技术,对三层交换技术、VLAN的划分及一些关键设备和应用系统的开发等等几个关键技术问题进行了研究。

In the research of advanced key techniques, the technique of nano-catalyst is developed and tested according to the requirement for the catalytic flame stablizer gas turbine and the related reaction model wil be fully construced. In the aspect of hydrogen shift and separation process, we are going to probe into various operating parameters for the water shift reaction and the membrane reactor alread constructed. Also, the high efficiency DPMS-based hydrogen shift and separation system that carry out both water gas shift and pressure swing absorption will be tested. The main task this year is to construct the proto-type clean hybrid power generation system.

前瞻关键技术研究方面,奈米触媒制备技术将依触媒驻焰气涡轮引擎之需求进行开发与测试,并建立相关反应模式;气化合成气转化与分离技术部分,将进行已建立水气转移反应与薄膜反应器之各项操作参数探讨,并进行以双孔径分子筛为担体,附加水气转移反应与变压吸附分离所建立之高效率分离富集H2方法之系统实测。

The results indicated cDNA probe coloration sensitivity of these three symptomless viruses are 5 pg,10 pg and 10 pg differently.

结果表明,这3种病毒探针的检测灵敏度分别为5、10和10 pg。

The developmental mechanism and physiological functions of synergid are attractive research topics, and some related new results, especially from molecular biology, provide new clues to probe the synergid functions.

近年来对助细胞的研究又取得了一些新结果,尤其是一些分子生物学的研究结果为揭示助细胞的功能提供了重要线索。该文总结了这方面的研究成果,并对助细胞的生殖功能进行了分析。

The DTI probe should be in contact with a flat area of either the tappet or the spring retainer.

DTI的探针应置于挺柱或锁夹的平面上。

Secondly, comparative experiments were carried out in different phase regions to probe the influence of pressure and the phase behavior of the mixed solvents on the tautomerism.

将紫外光谱及热力学方法相结合,测定了CO〓+乙醇、CO〓+正戊烷混合流体中EAA的异构化平衡常数,研究了超临界区、临界区和亚临界区EAA的异构化平衡常数随压力等因素的变化规律。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。