查询词典 presynaptic

Toosendanin (〓, FW 574, TSN), a triterpenoid derivative, is an active ingredient extracted from the bark of Melia toosendan Seib et Zucc which is used in Chinese traditional medicine as an anthelmintic vermifuge against ascarids. It was demonstrated to be a selective presynaptic blocker in neuromuscular junction and central synapses.

从驱蛔中药楝属植物根皮中提取的三萜化合物川楝素（toosendanin，〓，FW 574，TSN），是一种选择性影响神经递质释放，阻遏神经肌肉和中枢突触传递。。。

The results of these cellular experiments are quantitatively similar to the results of behavioral experiments with the same protocol and parameters, suggesting that activity-dependent amplification of presynaptic facilitation may make a significant contribution to classical conditioning of the withdrawal reflex.

这些细胞实验与同样方法和参数下的行为学实验有著同样的定量结果表明突触前的活动依赖性增幅对撤回反射中的经典制约有重大贡献。

However, we observed distinct abnormalities within presynaptic terminals of spinal MNs at the neuromuscular junction, as well as profound denervation.

无论如何，我们观察到神经肌肉接头处的脊髓运动神经元突触前末梢的明显的异常，还有显著的去神经支配。

The presynaptic neuron must be active and release glutamate, and the AMPA receptor in the postsynaptic cell must bind glutamate and depolarize the cell.

对NMDA受体功能的研究在众多的神经科学家中引起了轰动，因为受体充当了"同时检测器"。

By using freshly isolated SD rat cerebrocortical synaptosomes and KC1 as chemical stimulant to depolarize, we studied the effects of etomidate on KCl-induced increased intrasynaptosomal calcium concentrations, voltage-gated calcium channel subtypes on presynaptic membrane and neurotransmitters release from synaptosomes respectively, via neurochemical and inverse phase high performance liquid chromatographic methods.

我们利用SD大鼠新鲜分离的大脑皮层突触体作为研究对象，以KCl作为化学刺激剂去极化，采用神经化学方法(Fura-2作为钙离子指示剂)和高效液相测定法，分别就依托咪酯对去极化诱发突触体内钙离子浓度升高的影响，突触体膜上电压门控性钙通道亚型的作用以及由此引起的对神经递质释放的影响进行了实验研究。

SP can affect the function of DRG neurons by activing the non-selective cation channels combining with its selective NK1 receptor. ATP depolarize DRG neurons and make some sodium channels closed so that the amplitude of action potentials and Vmax decreased which result in decreaced releasing of neurotrasmitters from DRG neurons, the way is same like GABA-induced presynaptic inhibition by activing the non-selective cation channels possibly combining with P2X2/3-receptor.

SP可能通过开放非选择性阳离子通道从而影响DRG神经元膜的兴奋性；ATP通过与P2X2/3-R结合开放非选择性阳离子通道，使得A类神经元膜预先去极化，引起膜钠通道部分关闭，动作电位幅值降低，斜率Vmax减小，使神经末梢递质释放减少，其作用与GABA介导的突触前抑制类似。

This might be one of the mechanisms that underlie presynaptic inhibition in DRG.

这可能是腺苷参与镇痛的突触前抑制机制之一。

Agkistrodotoxin, a presynaptic neurotoxin and one of the two neurotoxins from the snake venom of Agkistrodon halys Pallas, has been further purified by DEAF -cellulose and CM-Sephadex column chromatography and vertical slab polyacrylamide gel electrophoresis.

本文在前文的基础上，改进了蝮蛇神经毒素的分离方法，纯化了蝮蛇毒中的两个神经毒素之一，突触前神经毒素Agkistrodotoxin，并对其生化特性进行了分析。

The transmission is conducted in the form of action potentials along the axon of DRG neuron to the presynaptic membrane in spinal dorsal horn. Action potential depolarizes the presynaptic membrane and activates the voltage-dependent Ca〓 channel. The influx of Ca〓 then triggers the release of neurotransmitter.

外界感觉信息以动作电位的形式沿DRG细胞轴突由外周传向DRG细胞在脊髓背角的突触前膜，导致细胞膜去极化，引起电压依赖性〓通道的开放，〓内流介导突触前膜神经递质的释放，从而完成感觉信息由外周向脊髓的传递。

The mPSCs induced by GABA released from the presynaptic boutons could be completely and reversibly blocked by 5μM bicuculline, which is the specific antagonist of GABAA receptor. These results indicate that GABA released from the presynaptic boutons may produce modulatory effects through binding with GABAA receptor on postsynaptic Vme neurons.

以上结果表明：突触前终扣内释放的GABA与分布于突触后的GABAA受体结合从而发挥对Vme神经元的调控作用，GABAA受体激活后，氯离子通道开放，Vme神经元胞体内外氯离子流动构成了GABA对Vme神经元的作用基础。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。