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One of the problems we have seen I that when we give a drug that reduces appetitive like the Melanocortin 4 receptor agonist, that that tends to raise the blood pressure and of course that is undesirable in treating hypertensive patients to have a further rise in blood pressure so we would like to understand the molecular signaling pathways in the brain that allow for appetite, metabolic function, and blood pressure to be differentially controlled and therefore attack those different targets in treating not only obesity but also hypertension.

我们所遇到的一个难题是,当我们使用一种药物减低食欲,如黑皮质素受体4,有可能会增加血压。当然,血压进一步升高对于治疗中高血压患者是不受欢迎的。所以在高血压和肥胖的治疗中,我宁愿了解脑影响食欲、代谢功能和血压的分子信号途径,由此寻找差异性控制、进而治疗不同的目标。

Correctional checking formula of melt flow ratio in injection molding was obtained by introducing a correction coefficient β which reflected the complexity degree of mold cavity. The results show that, the maximum flow ratio of 486 can be obtained when injection pressure ranges from 150 MPa to 160 MPa in Archimedes spiral mold for PP, while maximum flow ratio of 419 can be obtained when injection pressure ranges from 160 MPa to 170 MPa for PE. There is a local fluctuation phenomenon for flow ratio and corresponding injection rate in square spiral mold when injection pressure of 100, 120 and 150 MPa for PP and 130, 140 MPa for PE are reached respectively,and this phenomenon is more serious for good fluidity of melt. The average flow ratio in Archimedes spiral mold is 6% larger than that in square spiral mold for PP, and 4% for PE, the average flow ratio of PP is 19% bigger than PE in Archimedes spiral mold, and 15% in square spiral mold. The influence of the cavity profiles on the melt flow ratio is more significant for good fluidity of melt.

研究结果表明:在阿基米德螺旋线模具中,PP在注射压力为150~160 MPa时取得最大流动比485,PE在注射压力为160~170 MPa时取得最大流动比419;在方形螺旋线模具中,PP在注射压力为100,120和150 MPa,PE在注射压力为130和140 MPa时流动比及所对应的注射速率出现波动,且流动性好的熔体波动更为严重;PP在阿基米德螺旋线模具中的流动比均值较其在方形螺旋线模具中大6%,而PE大4%;在阿基米德螺旋线模具中流动比均值PP比PE的流动比均值大19%,而在方形螺旋线模具中PP的流动比均值比PE的大15%;流动性好的熔体受模具型腔轮廓特征影响大。

In the engine room, there is one independent self-priming electrical general bilge pump(65CWZ-11, delivery capacity: 36m3/h, pressure: 0.21Mpa), one bilge ballast pump (65CWZ-6, delivery capacity: 36m3/h, pressure: 0.42Mpa), one firefighting pump (65CWZ-6, delivery capacity: 36m3/h, pressure: 0.42Mpa), all of them can discharge the bilge water of engine room, steering gear room, cargo hold out of board through discharge valve via their own suction, sludge tank, suction valve box.

本船机舱设置独立的自吸式电动舱底总用泵(65CWZ-11,排量:36m3/h,压力:0.21MPa)1台,舱底压载泵(65CWZ-6,排量:36m3/h,压力:0.42MPa)1台,消防泵(65CWZ-6,排量:36m3/h,压力:0.42MPa)1台,均可将机舱、舵机舱、货舱的舱底水经各自的吸口、泥箱、吸入阀箱吸入,再经排出阀排至舷外。

As implicit pressure and explicit saturation method is selected to calculate black oil model and the bottom-hole pressure is introduced, the coefficient matrix of pressure equation becomes bordered seven-symmetrical matrix.

用IMPES法求解黑油模型,引入井底压力为未知数时,压力方程的系数矩阵变成了加边的七对角阵。

As implicit pressure and explicit saturation method is selected to calculate black oil model and the bottom-bole pressure is introduced, the coefficient matrix of pressure equation becomes bordered seven-symmetrical matrix.

IMPES法求解黑油模型,引入井底压力为未知数时,压力方程的系数矩阵变成了加边的七对角阵。

Product brief introduction: GXF is inclined shed fan to be bosomy shape structure, the characteristic with its small imports and exports expedited the velocity of flow of air current, pressure coefficient is tall, shed fan with general axis below the circumstance of equal opportunity order, its discharge pressure all is more than general axis to shed the discharge of fan, pressure.

制品介绍:GXF斜流风机为鼓型构架,其进岀口小的特征加速了气流的流速,压力参数高,同一般的轴流风机一样机号的境況下,其访问数量压力均大于一般轴流风机的访问数量、压力。

YXK-160 bit type control pressure gauge use the bourdon tube as the snsitive element, while controllingthe liquid medium pressure, itcan indicate the pressure value.

YXK-160 位式控制压力表采用弹簧管作为测压敏感元件,在对被测流体介质压力进行控制的同时,可同步指示出被测压力值。

Therefore, Boyle's law, a principle of air statics, may not be appropriate for measuring pressure changes of flowing air. In this study, we deduced equations for pressure changes inside pressure-type plethysmograph and then designed three experiments to testify the theoretic deduction.

为了研究气体流动本身对描记箱内压力是否产生影响,本研究采用空气动力学理论推导出压力型体积描记箱内压力变化的近似公式,并设计了三个实验对理论公式进行证明。

Fourth, we have effectual method to control the pressure, if we are unwilling to do one's best to lighten the pressure, strengthening motive force, we bring the limitless agony to oneself and others, without success of accomplishing in one move, if we can succeed in dealing with the pressure in life , we may just get oneself and encourage .

第四,我们有控制压力的行之有效的方法,如果我们不愿尽最大的努力减轻压力,增强动力,我们就回给自己及他人带来无限的痛苦,没有一蹴而就的成功,如果我们能够成功处理生活中的压力,我们才有可能获得自我激励。

Business card printing and membership card making pressure by lining thickness and drum Center distance between two methods for regulating, pressure should be to have a dot burliness printing, clear and colorful and bias at an affordable cost, and the amount imposed as small as possible, to control the dot gain deformation, tuning and accurate business card printing and membership card making pressure is important.

制卡和会员卡制作不张力是堵住包衬薄度和滚筒边缘距调度两栽办法得回,不张力该当是以印品具有网点单弱、图文澄辉、色彩灿艳和浓淡相宜为条件,并且承受度越小越好,把持网点放不小变形,调度不确的制卡和会员卡制作不张力不入格关头。

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