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Objective:This project chooses the classic Chinese medicine prescription on treating ADHD——Kongsheng Zhenzhong Pill and studies it\'s impact on the signal trasmission of the neurotransmitter DA of the prefrontal cortex-basal ganglial circuit loop in the center of the ADHD animal model——SHR.The project tries to make clear Kongsheng Zhenzhong pill\'s curative effect in animal experiment and explore in depth the mechanism of treating ADHD with Chinese medicine.

一、研究目的本课题选择中医药治疗ADHD的代表方剂——孔圣枕中丹，研究其对ADHD动物模型自发性高血压大鼠中枢前额叶皮质—基底神经节环路的神经递质DA的信号传导的影响，明确孔圣枕中丹在动物实验中的疗效，深入探索中医药治疗ADHD的具体机制。

However, there is few activations in those language-related area, including Broca's area, dorsolateral and ventrolateral prefrontal cortices, Wernicke's area and angular gyri.

同时，ROI分析进一步证明，左侧顶下小叶与顶上小叶区域与双侧的中央后回区域的激活量更为显著，但在任务之间没有显著的差异。

Moreover, neuroimaging studies demonstrated that the left posterior inferior frontal cortex, the bilateral supermarginal gyri and the dorsolateral prefrontal cortex were involved in code switching.

语言切换的神经机制研究则表明，左侧额下回、双侧缘上回和背外侧前额叶等脑区参与了双语者的语言切换过程。

RESULTS: Contrasts between VGS and fixation on a stationary target identified a network of activation that included the frontal eye fields, supplementary eye fields, prefrontal cortex, intraparietal sulci, and the areas of the visual cortex (MT/V5, V2/V3, and V1) in control subjects and patients.

结果：对VGS和固视于静态目标之间进行对比，结果表明患者和对照者的额叶视区、辅助眼区（、额前皮质、顶内沟以及视皮质某些区域(MT/V5， V2/V3， and V1)的网状系统被激活。

The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明，SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达，孔圣枕中丹组比盐酸哌甲酯组要高，且两者均低于对照组；豆状核多巴胺受体D2的基因表达，盐酸哌甲酯组要比孔圣枕中丹组高，且均低于对照组。

Objective: To observe the expression changes of Calretinin in the prefrontal cortex of the posfischemia Meriones Unguiculatus procerebrum and to provide the morphological facts for the further research of its function.

目的：观察蒙古沙鼠前脑短暂缺血后前额皮质Calretinin的表达变化，为进一步研究其功能及治疗提供形态学依据。

Acute Map also cause dopamine increases in medial prefrontal cortex and neostriatum, which results in the increasing of locomotor's activity and stereotypic behavior.

急性甲基安非他命也会引起额脑及纹状体中的多巴胺浓度增加，继而导致活动力上升及出现刻板行为和敏感化现象。

During the painful stimulus itself, there was increased activation in the right amygdala and decreased activation in the periaqueductal gray matter and rostral anterior cingulate and prefrontal cortices, areas responsible for cortical and subcortical pain modulation, in the depressed relative to nondepressed subjects.

在痛觉刺激本身时，右杏仁体的活性增加，而导水管周围灰质的活性是下降的，且喙侧前扣带回与额前皮质，负责皮质与亚皮质疼痛调控的区域，其活性相较于非忧郁受试者来说是下降的。

During the painful stimulus itself, there was increased activation in the right amygdala and decreased activation in the periaqueductal gray matter and rostral anterior cingulate and prefrontal cortices, areas responsible for cortical and subcortical pain modulation, in the depressed relative to nondepressed subjects.

在痛觉刺激本身时，右杏仁体的活性增加，而导水管周围灰质的活性是下降的，且喙侧前扣带回与额前皮质，负责皮质与亚皮质疼痛调控的区域，其活性相较於非忧郁受试者来说是下降的。

Pronounced differences were found in Left perisylvian/Language and Medial temporal/Memory systems, along with significant differences in Lateral/Prefrontal/Working memory and Anterior cingulate/Cognitive control and smaller, nonsignificant differences in Occipitotemporal/Pattern vision and Parietal/Spatial cognition.

左侧外侧裂区和颞叶中部存在显著的差异。前额叶与额叶侧部和前扣带回之间也具有显著差异。而枕颞叶和顶叶之间的差异较小，且没有显著性。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。