查询词典 prediagnostic

In peripheral blood obtained up to 77 months before a CLL diagnosis, prediagnostic B-cell clones were present in 44 of 45 patients with CLL.

45例白血病患者中，44例在CLL诊断前77个月内获得的外周血中发现了诊断前B细胞克隆。

RESULTS: On the basis of either flow-cytometric or molecular analysis, 44 of 45 patients with CLL (98%; 95% confidence interval , 88 to 100) had a prediagnostic B-cell clone; in 41 patients (91%; 95% CI, 79 to 98), the presence of the B-cell clone was confirmed by both methods. The presence of immunoglobulin heavy-chain variable genes was determined in 35 of 45 prediagnostic clones (78%).

结果：在流式细胞或分子分析的基础上， 45名白血病患者有44例（98 ％； 95 ％可信区间，88～100 ）具有诊断前B细胞克隆；在41例（ 91％； 95 ％可信区间， 79～98 ），B细胞克隆的存在得到了这两种方法的证实。45个诊断前克隆中有35个(78%)具有免疫球蛋白重链可变基因。

Objective: To investigate whether prediagnostic fasting glucose and insulin concentrations and insulin resistance are associated with subsequent incidence of exocrine pancreatic cancer in a cohort of male smokers.

目的：在一个男性吸烟人群队列中调查诊断前空腹血糖、胰岛素水平和胰岛素抵抗是否与外分泌型胰腺癌发生相关。

Furthermore, 27 of 35 of the IGHV sequences (77%) had mutations, with similar distributions after stratification either below or above the median time between the collection of the prediagnostic blood sample and the subsequent CLL diagnosis.

此外，35个IGHV序列中有27个（77 ％）有突变，对诊断前血液样本收集和随后CLL诊断的中位时间进行分层，突变具有类似的分布。

Context: Obesity, diabetes mellitus, and glucose intolerance have been associated with increased pancreatic cancer risk; however, prediagnostic serum insulin concentration has not been evaluated as a predictor of this malignancy.

背景：肥胖、糖尿病、葡萄糖耐受不良与胰腺癌发生风险升高有关。然而，诊断前血清胰岛素水平并不能作为这种恶性疾病的预测指标。

Patients and Methods: To investigate whether prediagnostic levels of plasma folate are associated with colorectal cancer– specific and overall mortality, we performed a prospective, nested observational study within two large US cohorts: the Nurses' Health Study and Health Professionals Follow-Up Study.

患者与方法：为了研究血浆叶酸与结直肠癌患者个别或整体死亡率的关系，我们在美国的两个研究样本之间进行了一项前瞻性队列研究。

We conducted a nested case-control study within four large, prospectie cohorts to inestigate whether prediagnostic plasma leels of IGF-I, IGF-II, and IGFBP-3 were associated with pancreatic cancer risk. Plasma leels in 212 cases and 635 matched controls were compared by conditional logistic regression, with adjustment for other known pancreatic cancer risk factors.

我们在四个大型的前瞻性群组中进行了巢式病例对照研究以调查是否诊断前期的血浆IGF-I， IGF-II，和 IGFBP-3水平与胰腺癌风险相关。212病例和635配对对照的血浆水平使用条件逻辑回归进行比较，使用另外已知的胰腺风险因子进行调节。

In this study, Dr. Anderson and colleagues analyzed prediagnostic serum samples and patient data from the Carotene and Retinol Efficacy Trial, a randomized chemoprevention trial that evaluated the effects of beta-carotene and retinol on the incidence of lung cancer among individuals at high risk for the disease.

参与Fred Hutchinson癌症研究中心公共健康科学小组的Anderson医师表示，我不知道目前是否有其他生物标记比这些更有效，但是在过去几年间，有许多关於找到可能标记的尝试，不过，并不是每个都有充分研究。

Some CT characteristics of BCSDH were studied first.Then,the risk factors for BCSDH were determined by logistic regression model from the following variates: age,gender,prediagnostic duration,site for injury force,coma experience and CT showing after injury.

先研究其CT表现，然后采用多因素Logistic回归分析从以下变量中，如年龄、性别、伤后&潜伏&时间、受伤着力部位、受伤时有无昏迷经过、伤时CT表现等确定BCSDH发生的影响因素。

Using six-color flow cytometry (with antibodies CD45, CD19, CD5, CD10, kappa, and lambda) and immunoglobulin heavy-chain gene rearrangement by reverse-transcriptase-polymerase-chain-reaction assay, we determined the association between MBL and subsequent CLL and characterized the immunoglobulin gene repertoire of the prediagnostic B-cell clones.

使用六色流式细胞术（使用CD45、CD19、CD5、CD10抗体、Ig κ和Igλ）和逆转录聚合酶链反应试验的免疫球蛋白重链基因重排，我们确定了MBL和随后的CLL之间的关系，明确了诊断前B细胞克隆的免疫球蛋白基因库。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。