查询词典 polymorphisms

The DNA adduct levels were irrelevant to genetic polymorphisms of CYP1A1 and GSTM1, but related to the CYP1A1 protein expression.

而DNA键结物含量和患者本身之CYP1A1和GSTM1的基因多形性无关，但和CYP1A1的蛋白表现有关。

In addition, the systematic study on the polymorphisms of XLF-343, which is an innovative and solid drug, indicated that at least 5 polymorphisms were obtained, including 4 crystalloids and 1 amorphism.

此外，还对创新固体药物XLF-343进行了多晶型问题的系统性研究，发现该化合物至少存在5种以上晶型，4种为晶态，1种为非晶态。

It is suggested that it is better to indicate the variability within breeds by average heterozygosity based on microsatellite polymorphisms, which showed high polymorphisms and codominant inheritance of the markers, where as differences between populations and even specific characteristics with in a population are reffected clearly and directly by RAPD.

由于微卫星标记多态性程度高且等显性遗传，因而通过它计算杂合度可以较好地反映群体内的变异；RAPD则在反映群体间的区别甚至某一群体的特征时可提供明确而直接的信息。

The gonadotropin releasing hormone receptor gene was studied as a candidate gene for the prolificacy of Small Tail Han sheep. Eight pairs of primers were designed to detect single nucleotide polymorphisms of exon 1, exon 2 and exon 3 of GnRHR gene in both high fecundity breeds and low fecundity breeds (South African Mutton Merino, Corriedale and Chinese Merino sheep) by PCR-SSCP. Only the products amplified by primers P4 and P7 displayed polymorphisms.

设计8对引物，应用聚合酶链式反应-单链构象多态性技术检测促性腺激素释放激素受体（gonadotropin releasing hormone receptor， GnRHR）基因外显子1、外显子2和外显子3在高繁殖力品种和低繁殖力品种（南非肉用美利奴、考力代和中国美利奴绵羊）中的单核苷酸多态性，同时研究该基因对小尾寒羊高繁殖力的影响。

As part of the Stroke Prevention in Young Women study, which is evaluating genetic and nongenetic ischemic stroke risk factors in young women, the investigators systematically searched the PDE4D gene for novel and known polymorphisms in 48 African-American women and 48 white women. These polymorphisms were then prioritized and genotyped in the entire study population of 224 cases of first ischemic stroke and 211 age- and race-matched controls.

年轻妇女中风预防研究里面的一部分，评估年轻妇女基因性和非基因性缺血性中风风险因子，研究者系统式蒐寻48位非裔美籍妇女和 48位白种妇女之PDE4D基因之新的和已知的多型体，这些多型体按基因型顺序排好，400位之中有224例首次缺血性中风，有211位是年纪和种族配对控制组。

BALB/c from Chongqing had polymorphisms at 7 sites and displayed polymorphisms at the D10Mit180 site comparing with BALB/c of Shanghai. DNA fingerprints of Wistar rats were studied with JL-2 multilocus prober and southern hybridization.

采用JL-02多位点探针和Southern杂交对Wistar大鼠基因组进行了DNA指纹分析，并对国内最具有典型的6个地区9个Wistar大鼠群体内和群体间进行了DNA指纹分析比较。

This study was designed to clone the duck FABP gene based on the sequences of chicken and mammal FABP gene by comparative genome and bioinformatics approaches; to investigate the expression characterization of FABP genes by RT-PCR; to detect the polymorphisms of FABP genes by DNA sequencing, PCR-SSCP methods, and to investigate the effects of FABP genes polymorphisms on growth and body composition traits in Kunshan sheldrake, Cherry Valley Meat duck and so on.

本研究以鸡、哺乳动物FABP基因序列为基础，通过比较基因组学和生物信息学等方法克隆鸭的FABP基因；采用RT-PCR方法研究FABP基因的组织表达特性。

Ofeffective 1st branches, length of main inflorenscence, effective siliques of maininflorenscence, density of main inflorenscence, length of silique, seed per sillique,1000 seed weight, total effective siliques per plant had significant positive correlationwith yield per plant. Polymorphisms between zhongshuang No.4 and H228 was examined by SSR primers. 152 primers Showed polymorphisms, and a linkage map containing 123markers, including 18 linkage groups was constructed. The total genetic distance ofthe map was 3483.1cM, and the average distance of two adjacent markers was28.32cM.

选用SSR引物对中双4号和H228间进行多态性检测，有152对引物在双亲间表现多态性，用这些引物分别对142个株系进行检测，构建了含有123个SSR分子标记、18个连锁群的连锁遗传图，总图距为3483.1cM，标记间平均距离为28.32cM，各标记在18个连锁群上的分布很不均匀，其中，第1、12、13、17连锁群上分布标记较多，其它连锁群上分布标记较少。

The purpose of the work is to investigate the frequencies and polymorphisms of HIV-1 resistant CCR5delta32,CCR2b-64I,SDF1-3′A alleles in Chinese Dai and Chingpaw populations.Whole blood samples from 101 Dai subjects and 113 Chingpaw were collected randomly and their genomic DNA were extracted with QIAgen Blood Kits.Allelic frequencies were identified by PCR-RFLP analysis.Allelic polymorphisms in Dai population or Chingpaw population and both sexes in the samples were analyzed by χ2 test.

为了调查HIV-1感染相关的等位基因CCR5△32、CCR2b-64I、SDF1-3′A在我国云南省德宏州傣族景颇族人群中的频率和多态性分布，此课题以101例傣族和113例景颇族人群为研究对象，应用PCR、PCR-RFLP(聚合酶链反应-限制性片段长度多态性)分析方法进行检测，计算突变基因频率；并对其群体分布、性别分布进行统计学分析。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。