查询词典 polymorphism

①Location of WD gene in Ch inese: Using pairwise linkage analysis and multipoint linkage analysis method, w e constructed a genetic map of DNA markers within D13q14.2-3 which refined the location of WD gene by restriction fragment length polymorphism and microsatellite polymorphism analysis;②Screen for mutations of WD gene in Chinese people: we detected the structure of 21 exons of WD ge ne in 45 patients from 39 pedigrees by PCR-SSCP(Single strand conformation poly morphism) and PCR-DNA sequencing technology, found a new mutation in exon 5 and nuclcotide sequence analysis showed it is a T insertion. We also conformed the Arg778Leu in exon 8, the highest frequence mutation point in Chinese people, wit h mutation rate 22.8%in total;③Carrier detection and presymptomatic diagnosi s of WD: Based on DNA recombination technology, we peformed successfully the gen e diagnosis in all individuals of 79 families with WD and built up a helpful spe cific enzyme cut method (PCR-Msp1) to detect the carrier and presympomatic patients in Chinese pe ople with WD.

①WD的基因定位研究：通过RFLP及微卫星多态性分析，应用两位点及多位点连锁软件，建立了中国人WD基因在D13q14.2-3区域的精细遗传连锁图谱，从而首次对中国人WD基因进行了精确定位；②WD基因突变研究：应用PCR-SSCP及DNA测序技术，对39个家系45名WD患者进行该致病基因的21个外显子突变筛选，发现WD基因5号外显子存在新的T插入突变，并证实中国人WD基因的突变热点为8号外显子，突变形式为Arg778Leu，其频率为22.8%；③WD的症状前诊断和杂合子检出：应用DNA重组技术对79个家系进行基因诊断，成功地进行了WD的症状前诊断和杂合子检出，并建立了WD的基因筛选的PCR-Msp 1酶切方法。

STR locidistribute extensively and have higher information, polymorphism, and its heredity is based on Mondel codominant inheritance. We usehalf-quantitative analysis of STR polymorphism loci, to set up a clinicalpractical method that is highly accurate in rapidly detecting and prenatalgene diagnosing Down syndrome.

STR广泛分布于人类基因组中，一般认为，人类基因组平均每6～10Kb就有一个STR基因座，STR有高度多态性并遵循孟德尔共显性遗传，具有操作简便、分型准确和丰富的多态信息量等特点，已成为第二代DNA分析技术的核心。

In order to understand insertion/delation polymorphism of the angiotensin-converting enzyme gene in pilots,and to explore the relationship between ACE gene I/D polymorphism and the perfomance of the pilots,the polymerase chain reaction was used to determine the genotypes for an I/D polymorphism in intron 16 of the ACE gene in 118 pilots and 96 healthy subjects as controls.

为了解飞行员血管紧张素转换酶基因插入或缺失多态性情况，探讨ACE基因多态性与飞行员耐力可能的关系，用聚合酶链反应扩增技术检测118例飞行员和96例健康对照者的ACE基因I/D多态性。

Using the methods of classical shape size measuring and chromosome analysis, we studied the morphological characters and Karyotype of Cobitis sinensis in Xiangjiang River. We also investigated the evolution line and Karyotype polymorphism of the C . sinensis by the methods of cytological classification and cytocatalytic. Our results suggest that the formation of chromosome polymorphism was concerned with heterologous hybridization and some of C . sinensis may perpetuate in a clonal manner by natural gynogenesis.

本文以湘江流域的中华花鳅为研究对象，运用经典的形态测量观察方法、染色体制片技术对中华花鳅的形态生态特征、染色体组型进行了初步研究：运用细胞分类和进化方法对中华花鳅的核型演化和核型多态现象的形成进行了分析，提出：其核型多态的形成牵涉到鳅科鱼类的异源杂交，某些中华花鳅可能是行雌核发育生殖的。

The products amplified by primer 2 had polymorphism. The sequencing results indicated that there were two nucleotide mutations( C→A and C→T )at exon 1183bp and 336bp of hircine GDF9 gene, but the two mutations did not cause amino acid change. The products amplified by primer 3 had polymorphism.

所设计的6对引物扩增产物中共有3对发现了多态，引物1经SSCP分析虽然没有发现多态但经克隆测序却在外显子1编码区前-4bp处检测到A→C的突变。

The activity of CYP2C19 enzyme demonstrates greater inter-individual and interethnic variations in humans. Genetic polymorphism is the common cause of inter-individual and interethnic differences in the metabolism of the same substrate. This polymorphism influences both drug response and disease treatment.

CYP2C19酶活性存在显著的个体差异及种族差异，它的不确定性严重影响了临床疗效和用药安全，而遗传多态性是产生这种差异的重要原因。

CAAT box" and "TATA box, potential regulatory motifs from transcription, and conserved cis-acting regulator elements were discovered within LTRs in the great number of sequences using plantCARE sortware.6 The insertional polymorphism of LTR-10 element within the genome of 8 wild species and 28 cultivars of Mallus Mill. was studied by sequence-specific amplification polymorphism.

分析获得的Tyl-copia类逆转座子的LTRs，其中含有启动子的结构特征"CAAT box"和"TATA box"及受不同胁迫条件作用的调控元件。6、基于苹果Tyl-copia类逆转座子LTR-10的SSAP技术在苹果属8个野生种和28个栽培品种中表现出了丰富的遗传多态性，多态性片段比例为88.2％。

Locusts, some caterpillars, castes of social insects, alary polymorphism in crickets, aphids and other Homoptera, and color polymorphism of butterflies are examples of insect polymorphism.

同一性别昆虫，还可分化成具有不同形态和生殖机能的，或在其&家族&中负担不同职能的个体群。蚂蚁、白蚁、蜜蜂等社会性昆虫，除雌雄二型外，还有职蚁和职蜂。

Different genotypes were determined in Luxi monotocous cows, Luxi twinning cows, Chinese Simmental cows, Angus cows and Simmental×Mongolia cows by restriction fragment length polymorphism. The value of polymorphism information content indicated that this was a moderate polymorphism in Luxi monotocous cows and Luxi twinning cows.

运用PCR-RFLP法验证并分析该位点在鲁西牛双胎群体和单胎群体及中国西门塔尔牛、安格斯牛和西蒙杂交牛单胎群体间的多态性，结果表明，在鲁西牛双胎和单胎群体中分布A、B两个等位基因，处于中度多态。

ALb and Ams of Angora and Tibetan foat had only one phenotype,they did not present polymorphism.The Tf of Angora goat had not polymorphism,but that of Tibetan goat had its polymorphism,The Akp,LDH and Es in goats of both breeds had polymorphisms,eapecially the phenotype of Es was more complex.

安哥拉山羊和藏山羊 Hb、Alb 和 Amy 均只有一种表型，未表现出多态性，安哥拉山羊 Tf 也无多态性，藏山羊则有多态性；而两个品种山羊的 AKP、LDH 和 Es 均表现出多态性，尤其是 Es 的表型更为复杂。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。