查询词典 pneumococci

Pneumococci are frequently isolated from the nasopharynx of 40% healthy people, and few people exhibit symptom.

肺炎链球菌是条件致病菌，40%的健康人鼻咽部有寄生，当环境发生变化时才感染致病。

Little is known about how pneumococci became pathogenity from parasitism. Natural transformation is a kind of gene transfer manners in bacteria.

自然转化是细菌之间基因转移的一种方式，肺炎链球菌是目前发现转化效率最高的一种细菌。

To further understanding when and where pneumococci formed transformation in vivo so as to study the influence of pneumococcal transformation to its virulence, we constructed a pneumococcus 22G its transformation forming could be reported by EGFP.

为进一步了解肺炎链球菌在宿主体内转化发生的情况，便于深入研究体内细菌转化对其毒力形成的影响，本研究构建了绿色荧光报告细菌转化发生的肺炎链球菌菌株22G。

Losing competence might affect their β-lactam resistance, and the consequences were different in different strains.4. To further understanding when and where pneumococci formed transformation in vivo so as to study the influence of pneumococcal transformation to its virulence, we constructed a pneumococcus 22G itstransformation forming could be reported by EGFP.

肺炎链球菌的感受态形成可诱导ciaH和cpoA的表达增加，其感受态缺陷影响到其对β-内酰胺类抗生素的敏感性，但不同菌株影响的结果不同。4、为进一步了解肺炎链球菌在宿主体内转化发生的情况，便于深入研究体内细菌转化对其毒力形成的影响，本研究构建了绿色荧光报告细菌转化发生的肺炎链球菌菌株22G。

With the loss of spleen function, antibody formation, opsonization and alternate complement production are all affected, producing an increased risk of infections, especially to encapsulated organisms (pneumococci, meningococci, salmonella).

随着脾脏功能、抗体形成、补体调理作用和交替产生作用的失去，机体感染几率增加，特别是对有夹膜的生物如肺炎球菌、脑膜炎球菌、沙门氏菌。

Be specific for Streptococcus pneumoniae, were used to identify 49 alpha-hemolytic streptococcal isolates suspected of being pneumococci.

三种PCR检测方法和一个商品化的试剂盒被用于鉴定49株疑似肺炎链球菌的有a溶血的链球菌，这四种方法都基于对16SrRNA基因的杂交，而且都声称对肺炎链球菌有很好的特异性。

We found the psaA-specific PCR to be the genotypic technique best suited for the identification of genuine pneumococci and optochin-resistant pneumococci.

我们发现psaA特异性PCR是最适合鉴定真正的和optochin耐药的肺链的一种基因技术。

In this study, first time, we investgated the molecular mechanism of pneumcoccal pathogenity, including virulence formation and resistance to β-lactams, on the point view of transformation. 1. In order to offer methods and pneumococci strains for later study, a transformation model of Streptococcus pneumoniae in laboratory was well established, by inducing pneumococci into transformation with CSP.

研究包括以下四部分内容：1、为后继的研究提供方法学支持和所需菌株，本研究利用CSP诱导细菌转化发生，建立了肺炎链球菌的实验室转化模型；并构建了肺炎链球菌转化缺陷菌株，通过抗生素培养基培养和PCR鉴定菌株构建成功。

Using this model three competence-deficient pneumococci, which was identified by PCR and transformation experiment, were constructed. It is found different strain has different bacterial optimal density for being induced into competence. The optimal density for strains 1, 2 and 22 was 0.1, 0.08and 0.07 respectively. The optimal condition for transformation is c plus y culture at pH8.0. In c plus y culture at pH6.8, which restrained pneumococci forming transformation naturally, pneumococci could be induced to form transformation by CSP.It is concluded that we could induce different S.pneumoniae by CSP into competence in their optimal density in laboratory. 2. It was discussed the relationship between pneumococcal transformation formation and its opportunistic pathogenesis. Comparing their virulence with that of parental strains by challenging mice intraperitoneally and adhering to ECV-304 cell respectively.

结果表明不同肺炎链球菌株的转化最适菌密度不同，1、2和22号菌株的最适转化密度分别为0.1、0.08和0.07；用于转化的CTM培养基最适为pH 8.0的C+Y培养基；在自然转化下不能诱导转化发生的pH 6.8的C+Y培养基中，使用CSP诱导，也能促使细菌发生转化，只是转化效率较低；结论：实验室条件下，不同细菌在一定菌密度时可利用CSP诱导肺炎链球菌成为感受态发生转化。2、为探讨肺炎链球菌转化对毒力表达的影响，本研究分别通过体外粘附人脐静脉血管内皮细胞ECV-304和体内小鼠毒力实验观察1、2和22号肺炎链球菌和其转化缺陷菌株1t、2t和22t毒力的差异。

85 And 119486/79. They are a novel type of antibiotic having both the wide antibacterial spectrum and high safety of penicillin and cephem antibiotics belonging to beta -lactam antibiotics, as well as the potent antibacterial activity and high beta -lactamase stability of carbapenem antibiotics.Sodium-(5R, 6S)-6-[-1-hydroxyethyl]-7-oxo-3- [-2-tetrahydrofuryl]-4-thia-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylate 5/2 hydrate (faropenem sodium, hereinafter referred to as compound 1) is currently used as an oral drug for various infectious diseases and is reported to show potent antibacterial activity against not only methicillin-sensitive Staphylococcus aureus, Streptococcus pyrogenes and Streptococcus pneumoniae but also gram-positive bacteria for which conventional beta -lactam drugs have proved ineffective such as penicillin-resistant pneumococci, oral staphylococci and enterococci, also showing a wide antibacterial spectrum covering gram-negative bacteria such as Haemophilus influenzae and anaerobic bacteria such as the genus Bacteroides, which activity is due to its novel skeleton penem ring (Kagaku Ryoho no Ryoiki The Field of Chemotherapy, Vol.

他们是一种新型的抗生素都具有广泛的抗菌谱和高度的安全青霉素和cephem抗生素，属于β-内酰胺类抗生素，以及作为强大的抗菌活性和高β-内酰胺酶稳定的碳青霉烯类antibiotics.sodium -（ 5 R ， 6 S ）-6 -[ - 1 -羟乙基] - 7 -氧- 3 - [ - 2 - t etrahydrofuryl] - 4 -硫杂- 1 -氮杂双环[ 3 。2.0]庚- 2 -节能- 2 -羧酸5 / 2水合物（法罗培南钠，以下简称为化合物1 ）是目前用来作为口服药物，为各种传染病和报道，以显示强大的抗菌活性，不仅对甲氧敏感的金黄色葡萄球菌，链球菌pyrogenes和肺炎链球菌，但也克阳性菌为常规β-内酰胺类药物已证明无效，如青霉素耐药pneumococci ，口腔葡萄球菌和肠球菌，也显示出广泛的抗菌谱，包括革兰阴性菌如流感嗜血杆菌和厌氧菌如属杆菌，这活动是由于其新颖的骨架青霉烯环（（化学ryoho没有ryoiki领域的化疗），第13卷，第10号，第74-80 ， 1997年）。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了