查询词典 pharmacology

Institute of Pharmacology and Toxicology , Beijing 100850, China

军事医学科学院毒物药物研究所，北京 100850

Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China

军事医学科学院毒物药物研究所，北京 100850

The article consult literatures at home in recent years and summarizes the extraction technology and the development in pharmacology research on Trollius chinensis Bung in order to provide the reference basis for clinical application.

本文通过查阅国内相关文献资料，对金莲花的提取工艺及药理学研究进展进行综述，为其在临床中的应用提供参考。

Trollius chinensis Bung is a kind of commonly used drug in traditional Mongolian medicine and enjoys great application value in pharmacognosy, pharmaceutical chemistry, pharmacology, pharmacy and clinics. There are extensive foreground to develop new drugs from it.

金莲花为蒙医常用药，在生药学、药物化学、药理学、药剂学和临床等方面都具有很高的应用价值，对其进行药物开发具有广阔的前景。

Department of Pharmacology,Shantou University Medical College,Shantou 515041,China;2 Department of Uropoiesis and Rheumatology,The First Affiliated Hospital,Shantou University Medical College,Shantou 515041,China

作者：周燕琼，郭福晓，贾强用，张艳美，郑燕珊，李乐娜，石刚刚作者单位：汕头大学医学院第一附属医院泌尿风湿病区，广东汕头 515041

To get the message in initial of the pharmacology empirical method of the drug's extraorgan or in corpore.

初步了解药物的体外和体内药理学实验方法。

Methods: Integrated and disrepaired skins in the rats were smeared with Salicylic AcidPhenol Liniment by the maximum tolerated dose only. The toxic reaction of the animals were observed and recorded continuously from the beginning of using the drug to 7 days, and evaluated by using the general standard of the reaction of skin stimulation in pharmacology. Animals were executed by taking off acanthi and blood was collected to check up the periphery blood routine and serum biochemistry at the end of the observation of the rats. And after the dissection, the pathological change of main visceras, such as heart, brain, liver and kidney were observed with naked eye and pathological slices. The data of this experiment was used to calculate the value of LD50 by using Bliss rule.

观察大鼠完整皮肤及破损皮肤一次性涂抹最大耐受量的小儿水杨酸苯酚搽剂所产生的毒性反应情况，从给药0时起至7 d连续观察记录动物的急性毒性和45 d连续的长期毒性反应，以皮肤刺激反应标准进行评分作毒理等级评价；对存活动物在观察结束时进行高位脱椎处死采血检测外周血常规和血清生化，解剖后裸眼和病理切片观察心、脑、肝、肾等主要脏器的病理变化。

Pharmacology function】Huang An the AN oxygen Mi Ding be in the Huang An medicine to suppress the germ a very strong kind of the function to synthesize anti-virus medicine, because of it with for germ to synthesize folic acid demand of to ammonia Ji the benzene be sour to have likeness on the structure, exchange with PABA to contend for two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids, end influence nucleic acid protein of synthesize, repress thus germ of growth breed, to variety E-and E+very strongly repress a function.

磺胺间甲氧嘧啶是磺胺类药物中抑菌作用极强的一种合成抗菌药物，因其与细菌合成叶酸时所需要的对氨基苯酸在结构上具有相似性，与PABA兑争二氢叶酸合成酶，阻碍细菌合成二氢叶酸合成酶，阻碍细菌合成二氢叶酸，最终影响核酸蛋白质的合成，从而抑制细菌的生长繁殖，对多种E-及E+有很强的抑制作用。

They conjectured that the most exciting new business applications of chemistry would be in pharmacology.

他们由此推断，化学最令人兴奋的新商业应用将出现在药理学领域。

WANG Wei-Ting, GUO Lian-Jun, QU Ling, WANG Fang, LU Qing, QIAN Jia-Qing(Department of Pharmacology, Tongji Medical College, Huazhong Universityof Science and Technology, Wuhan 430030, China)By using decapitating, intravenous injection of saturated MgCl2 and legation of bilateral carotid arteries with vagi, theeffects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethyl- amino) propane hydrochloride on survival time in mice were studied. With the model of cerebral ischemia for 20 min and reperfusion for 10 min, effects of DDPH on the superoxide dismutases activity and malondialdehyde content in brain tissue and pathological changes were studied.

采用断颅，iv饱和MgCl2溶液及结扎双侧颈总动脉和迷走神经等法造成小鼠脑缺血模型，观察1-(2，6-二甲基苯氧基)-2-（3，4-二甲氧基苯乙氨基）丙烷盐酸盐对小鼠脑缺血后存活时间的影响；采用小鼠脑缺血（20 min）再灌注(10 min)模型，观察DDPH对脑组织超氧化物歧化酶活性，丙二醛含量及组织病理损伤的影响。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。