查询词典 peptide

BmK IT2 is worthy of being considered to be a kind of new algesia peptide drug.

BmK粗毒和BmK I诱导的大鼠脊髓背角氨基酸类神经递质的释放采用微透析采样与高效液相色谱荧光检测技术，分析BmK粗毒和其主要致死成分BmK I诱发炎症痛过程中同侧脊髓背角氨基酸含量的动态变化。

A peptide antibiotics gene from Amaranthus hypochondriacus, Ah-AMP, was amplified by PCR and cloned. Sequence analysis results revealed that this gene is 261bp in length encoding a precursor polypeptide of 87 amino acid residues.

本文通过PCR技术从苋属植物千穗谷的总DNA中扩增出苋菜多肽抗生素的核基因片段，序列分析结果表明该基因长261bp，编码一个由86个氨基酸组成的Ah-AMP前体多肽。

Molecular cloning and characterization of the novel lection gene. Primers were designed based on conserved sequences of other lectin genes from Amaryllidaceae. A novel lectin gene was isolated from Zephyrathes grandiflora. The full-length cDNA of Zephyrathes grandiflora lectin was 955bp, containing an open reading frame (576bp) encoding a peptide of 191 amino acids. The gene was named as zga (Zephyrathes grandiflora agglutinin), with its encoding protein showing 59% similarity to GNA.

基因克隆及序列分析：根据石蒜科植物凝集素的保守区段，设计引物，采用RACE技术从韭莲中克隆出长度为952bp的新凝集素基因，包含了完整的编码序列(576bp)，它编码一个全长191个氨基酸的蛋白，与雪花莲外源凝集的相似性达59％，被命名为ZGA(Zephyrathes grandiflora agglutinin)。

The results showed that C-terminal amidation was important for antibacterial peptide's function.

通过实验认为c-末端酰氨化对抗菌肽的抗菌活性很重要。

We cloned the Rana temporaria chensinensis David skin cDNA using a PCR strategy and detected its activity in rana using a antibacterial protein assay against Micrococcus luteus. The cloning was based on a report of GenBank. The deduced amino acid sequence resulted in 53 amino with 46% identity to amphibia. RT-PCR was used to detect peptide mRNA in Rana temporaria chensinensis David.

我们用提取中国林蛙皮肽总RNA，逆转录合成cDNA，PCR扩增得到DNA片段，并与GenBank上登陆的其他蛙类的皮肽抗菌肽序列进行比较，发现此序列是一个新的蛙皮肽抗菌肽序列。

Therapies based on glucagon-like peptide 1 and amylin have now been introduced into clinical practice.

基于高血糖样肽1和淀粉不溶素的治疗方法现已进入临床实践。

Beta cells - Pancreatic cells responsible for the production of insulin, amylin and C-peptide

细胞—负责产生胰岛素、胰淀素和C肽的胰岛细胞。

The expressed apoE protein in central neuronal system functions potentially in deposition and clearance of amyloidal peptide, sustaining the stabilization of microtubule proteins, cellular signal transduction, immune regulation, glucose metabolism and oxidation stress.

中枢神经系统中的apoE对脑组织淀粉样蛋白的沉积与清除、微管蛋白稳定性的维持、细胞信号转导、免疫调节、葡萄糖代谢、氧化应激等都有潜在的作用，apoE在体内发挥十分重要的生物学活性。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

SC acan turn pneuma fine, add appetite, increase activity and improve color pattern and anischuria of RHR rats.SC didn't have evidence effect on SHR rats'body weight, but can increase RHR rats'body weight. 3.3.3 Find The effect on endothelin、nitrogen monoxidum、atrial natriuretic peptide and renin-angiotensin system of SC .

3.3.3三草降压汤对血浆内皮素、一氧化氮、心钠素及肾素-血管紧张素系统的影响 SC能明显降低SHR、RHR两种高血压大鼠模型血浆ET浓度、升高血浆NO浓度、调整二者的平衡，这可能是其发挥降压作用的重要机制。

As of Tuesday, Google's results were still censored in China.

截至周二，谷歌的搜索结果仍受中国审查。

In order to make the positive action increase and negative one decrease, the sub-forces of the social factors must be adjusted to form a centripetal force.

在这一过程中，人的主体性发挥是社会有机体健康发展的灵魂。