查询词典 pentylenetetrazol

ABSTRACT: Objective To study the effect of active ingredients of bupleurum chinensis D C. on GABA of hippocampus of chronic kindling induced by pentylenetetrazol in rats.

目的 研究柴胡总皂甙对戊四氮慢性点燃癫痫模型大鼠海马区γ氨基丁酸表达的影响。

Using HPLC separation and receptor binding assay, the present study demonstrated that the principle in the water extract of Huangqin acted on the BDZ binding site was not baicalin, wogonin or chrysin. In vivo study, WEH had no significant effect on pentylenetetrazol-induced clonic seizures in mice, although it could inhibitmaximal electroshock-induced tonic seizures with an ED50 of 3.6g/Kg.

本研究中，藉由高效率液相层析术与接受器结合实验评估，证实黄苓水抽提物中作用在BDZ结合处之主要成分，并不是黄苓甘、泛黄苓素或chtysin。

Pentylenetetrazol-kindling animal model is ideal epilepsy model to study epileptogenous mechanism.

神经细胞凋亡是神经细胞死亡的一种形式，也是异常兴奋性突触环路形成的重要原因。

To avoid the interference of seizure, the epileptogenesis animal model, i.e animal model before seizure was usd to study epileptogenous mechanism so that the authentic epileptic pathological features could directly been observed.

寻找合适的动物模型是研究的关键，点燃是一种癫痫形成现象，戊四氮(pentylenetetrazol，PTZ)是一种诱导癫痫的急性和慢性点燃模型以研究癫痫的发病机制的中枢神经系统兴奋药，PTZ点燃大鼠已被广泛用作研究癫痫的理想动物模型。

Pentylenetetrazol is a central nervous system drug that induce chronic and acute epilepsy model to study epileptogenous mechanism .Kindling is a natural epileptogenous phenomenon.

我们前期研究工作发现：应用电镜、Timm染色等从形态结构方面已证实在点燃前神经元发生了可塑性改变包括苔藓纤维芽生，新突触形成(突触密度增大或数量增多)与突触重排等，但这些只是一个初步探索，仍不能够说明问题的全部，如其分子生物学基础、神经元凋亡情况等尚不清楚，需进一步研究探讨。

Purpose To establish and appraisement the kindling model in rat induced by pentylenetetrazol.

目的 建立戊四氮点燃的大鼠慢性癫癎模型。

Methods:By pentylenetetrazol kindling in chemical method, we built the chronic epilepsy model.

采用戊四唑化学点燃方法，建立慢性癫痫模型。

Methods Animal model of epilepsy was established by pentylenetetrazol induction in rats.

采用戊四氮致疒间大鼠模型，检测癫疒间发作后神经细胞凋亡、NOS和NF- B的变化。

Severe seizure persisted after injection in high dose of pentylenetetrazol （60 mg/kg）group.

模型稳定、持久，点燃率较高、死亡率较低，为理想的致痴诱导剂量。

Objectives:To establish a model of status epilepticus induced by pentylenetetrazol,and to explore the relationship between the PTZ induced seizure and the epileptogenesis.

目的：建立一种戊四氮致癫癎状态模型，并探讨PTZ 致惊厥与癫癎形成之间的关系。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新