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Among them, 20 patients were candidates of valve replacement and 18 PDA and pericarditis had their blood samples taken before operation,and 1,2,24 and 48 hours after closure of thorax for measurement of concentrations of CK、CK-MB and TnT,together with ECG recording. Results Of the 60 patients, concentrations of cTnT before operation were normal; 2 hours after aortic unclamping, the correlation coefficient between cTnT and aortic clamping was r = 0.873( P<0.01), the regression analysis showed Y = 0. 019X-0. 026. Of the 20 patients, ECG showed the myocardium was ischemic; CK、CK-MB and cTnT all rose significantly, reaching the peak after closure of thorax. Of the 18 patients, the ECG and cTnT before operation and after closure of thorax were normal; except 2 patients with pericarditis.

结果 60例瓣膜手术患者术前cTnT均在正常值范围内,主动脉开放后2 h时,阻断时间和cTnT的相关系数为r=0.875(P<0.01),回归方程为Y=0.019X-0.026;其中20例瓣膜手术患者心脏经过阻断后,心电图有缺血性改变,周围血液中的CK、CK-MB和cTnT均有明显升高,分别在关胸后2 h达到高峰,数值分别为术前的12.6、9.2和257倍;18例行动脉导管结扎和心包剥脱术的患者术前和关胸后的心电图和血液中的cTnT均正常,CK和CK-MB除2例心包炎患者关胸后出现明显变化外,余均未见改变。

By 18 to 24 hours after infusion, the emesis typically subsides, only to recur and reach a second peak at approximately 48 to 72 hours after receipt of the agent.

注射18至24个小时后,呕吐状况缓解至正常,大约48至72个小时后才迎来第二个高峰。

Fod AR5395 the variation of peak flux Fx of soft X-ray exhibits a periodicity about 24.3 hours, the periodicity for the occurrence rate Nx of X-ray flares is about 12.2 houds, and the area Sx of sunspot groups varies with 24.4 hours period.

观测资料分析表明,AR5395活动区演化具有周期性的特征,软X射线峰值流量F变化周期为24.3小时,X射线耀斑出现率N_x,具有12.2小时的周期性,活动区黑子群面积S_x的变化呈现24.4小时的周期。

It is obviously that the number of VECF positive cells in the hippocampus and cortex increased reactively after HI compared with the control group (p.05) and reached peak 12 hours and persistent to 24 hours.

VEGF蛋白在大鼠缺氧缺血脑损伤后的表达增强,即刻有增加,12小时达高峰持续至24小时后下降。

In group C, the level of intracellular calcium increased persistently and the peak value was at 2 hours post-CPB、The activity of calcium pump and sodium pump increased temporarily at the begining of CPB, the lowest value was at 2 hours post-CPB.

结果表明:对照组转流中红细胞钙持续升高,转流后2小时达高峰;钙、钠泵活性在转流开始一过性升高,此后下降,转流后2小时最低。

As the DDP group A549DDP cells were treated with IC10 of cisplatin for 48 hours. As the DDP+Rh2 group A549DDP cells were treated with IC10 of cisplatin and IC5 of gensenoside Rh2 for 48 hours. As the controlling group A549DDP cells were not treated with any kinds of drugs. Changes in cellular morphology were observed by fluorescence microscopy. Peak value apoptosis of A549DDP cells were inspected by flow cytometry. State of PTP was evaluated by ultraviolate spectrofluorometer. Changs of calcium in cells and membrane potential of mitochondrion were determined by flow cytometry. Release of cyt-c from mitochondrion with westton blot Radiative activity of〓Tc-MIBI ingested by cells was measured withγcounter. Results: IC50 of cisplatine to A549 cells was 24uM.

以无毒浓度的Rh2单独作用于A549DDP细胞作为Rh2组,以低效浓度的顺铂单独作用于A549DDP细胞作为DDP组,以无毒浓度的Rh2和低效浓度的顺铂联合作用于A549DDP细胞作为Rh2+DDP组,作用时间为48小时,以不加药物干预作为对照组,Hoechst33258染色荧光显微镜下观察细胞形态的变化,流式细胞仪检测细胞凋亡峰;紫外光分光光度计检测线粒体PTP开放情况,流式细胞仪检测细胞内钙离子浓度及线粒体跨膜电位的变化,Westton blot检测线粒体内细胞色素C释放情况及Caspase-3的活性,γ计数仪检测细胞摄取〓Tc-MIBI放射性活性。

The pneumodynamic parameters such as peak airway pressure、oxygen index were measured at the following points: before surgery,the end of muf,6 hours,12 hours after end of cardiopulmonary bypass.

选取行二尖瓣膜置换术的46例患者,分为对照组和改良超滤组,对照组行常规体外循环,改良超滤组在体外循环后应用改良超滤,在转流前(t1)、转流结束(t2)、术后6 h(t3)、术后12 h(t4)测定失业保险中心气道峰压、吸气平台压、潮气量、呼吸频率、氧合指数,计算肺泡-动脉血氧分压差p(a-ao2和气道阻力,记录术后呼吸支持时间。

METHODS 46 patients who underwent mitral valves replacement were randomly divided into MUF group(n=24) and control group(n=22) without MUF. The pneumodynamic parameters such as peak airway pressure、oxygen index were measured at the following points: before surgery,the end of MUF, 6 hours, 12 hours after end of cardiopulmonary bypass.

选取行二尖瓣膜置换术的46例患者,分为对照组和改良超滤组,对照组行常规体外循环,改良超滤组在体外循环后应用改良超滤,在转流前(T1)、转流结束(T2)、术后6 h(T3)、术后12 h(T4)测定记录气道峰压、吸气平台压、潮气量、呼吸频率、氧合指数,计算肺泡-动脉血氧分压差P(A-aO2和气道阻力,记录术后呼吸支持时间。

METHODS 46 patients who underwent mitral valves replacement were randomly divided into MUF group(n=24) and control group(n=22) without MUF. The pneumodynamic parameters such as peak airway pressure、oxygen index were measured at the following points: before surgery,the end of MUF, 6 hours, 12 hours after end of cardiopulmonary bypass.Ventilatory support time was also measured.

选取行二尖瓣膜置换术的46例患者,分为对照组和改良超滤组,对照组行常规体外循环,改良超滤组在体外循环后应用改良超滤,在转流前(T1)、转流结束(T2)、术后6 h(T3)、术后12 h(T4)测定记录气道峰压、吸气平台压、潮气量、呼吸频率、氧合指数,计算肺泡-动脉血氧分压差P(A-aO2和气道阻力,记录术后呼吸支持时间。

The peak of stimulatory action was at 36 hours and 72 hours post-rhIL-7 treatment respectively.

将白血病细胞与100ng/ml浓度rhIL-7在37℃,体积分数为5%CO〓,饱和湿度条件下分别孵育18小时、36小时、72小时和120小时,结果显示白血病细胞在rhIL-7诱导后18小时B7-1和B7-2的表达开始增加,到36小时和72小时达高峰。

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呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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