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The Wilcoxon signed rank test was applied for comparison of sperm quality.. RESULTS: In total, 67 varicocelectomies were performed. Of the patients, 37(66.1%) were adults and 19(33%) were adolescents. In 36 infertile patients (64.3% of 57 patients), 8 had bilateral varicoceles. Oligospermial was noted in 8 of the 36 infertile patients (22.2%), 19 (52.8%) had asthenospermia, and 9 (25%) had oligoasthenospermia.

结果:在总计上,我们完成了六十七个显微外科精索静脉切除手术,在这些病人中,有三十七个(66.1%)是成年人和十九个(33.9%)是青春期的患者,在三十六个(占五十六个患者的643.3%)的不孕病人中,有8个患者有双边精索静脉曲张,在这三十六个不孕病人中有八个病人(22.2%)是oligospermia,十九个(52.8%)是 asthenospermia,和九个(25%)是oligoasthenospermia。

Results Critical stenosis or occlusion of contralateral arteries were found in the siphonic part of internal carotid artery in 6 patients, terminal ICA or proximal middle cerebral artery in 6 patients, and distal MCA in 1 patient. Seven patients had proximal ICA occlusion. The brain MRI showed typical watershed cerebral infarctions in 8 patients.

结果 所有患者均存在对侧颅内外血管严重狭窄或闭塞,其责任血管分布:颈内动脉虹吸段6例;颈内动脉末端或大脑中动脉起始部6例;大脑中动脉的M2段1例;颈内动脉起始部7例。8例头颅磁共振显示典型的分水岭脑梗死。6例行血管重建治疗,临床未再发作。

Results Analysis of the expression of proteins of JAK2 in leukemic blasts, there was no detectable constitutive expression of phosphorylated JAK2 in all the AML samples analyzed; Furthermore, we could detect a constitutive activation of STAT 3 by immunoprecipitation of the targeted protein in primary leukemic blasts from 3 of 11 AML patients without any cytokine treatment; Pretreatment clinical characteristics, and treatment regimens did not differ significantly between patients with and without constitutive STAT3 activity, there was not significant relation between the constitutive activation of STAT3 and the FAB subvariety and chromosome karyotype; However, the 3 patients with constitutive STAT3 activity seemed to have adverse treatment outcome, one did not show remission, the other two patients relapsed shortly after remission; Consistent with the above-mentioned result, leukemic blasts from the 3 samples with constitutive expression of STAT3 showed higher percentage of spontaneous apoptosis and S-phase cells.

在实验研究基础上,本研究进一步运用免疫沉淀和Western Blot印迹方法,检测AML患者原代细胞JAK2和STAT3活化情况,并分析了STAT3活化与AML患者预后有关指标改变的关系。结果我们的初步研究发现,11例AML患者中,有3例呈现STAT3组成型活化(STAT3阳性,下同),无一例呈JAK2组成型活化。上述3例STAT3组成型活化与FAB分型和染色体核型改变未见明显相关性;在此3例患者中,1例未取得缓解,另外2例虽然取得短暂缓解,但均在二个月内复发。上述3例STAT3阳性AML患者S期白血病细胞百分率数值较组高,而凋亡率数值较低。

Methods CHD patients were proved by coronary arteriongraphy. 64 patients with type 2 diabetes in combination with CHD were enrolled in group A and 98 patients with simple CHD served as group B. Patients of group A were subdivided into 3 groups based on scalar of the stenotic coronary artery, viz 1 rarnus, 2 rami and 3 rami affection groups, and urinary albumin level was determined. In group A, age, course of DM, BMI, BP, BS, GHbA1c, blood-fat, UAL serving as iv, and affection sum and stenosis index serving as dv, ran polynary gradual regressive analysis.

随机选取经冠状动脉造影确诊的冠心病患者,其中2型糖尿病合并冠心病患者64例为A组,单纯冠心病患者98例为B组,比较两组患者的临床资料和冠状动脉病变情况。A组患者根据冠脉病变支数分为3个亚组,即l支、2支、3支病变组,比较亚组间的尿白蛋白水平;A组患者以年龄、体质量指数、糖尿病病程、血压、血糖、糖化血红蛋白、血脂、尿白蛋白为自变量,分别以病变数、冠脉狭窄指数为因变量进行多元逐步回归分析。

objective to comprehend the characteristic of dyshidrosis and change of sympathetic skin responses in hepatolenticular degeneration patients.methods 66 patients with hld was investigated in information of sweeting and examined with ssr.results dyshidrosis was found in 36 patients among the 66 patients with hld,which most manifested decreased sweating in distal end of extremities combining compensating partly increased sweeting.

目的:研究肝豆状核变性患者出汗障碍的特点、皮肤交感反应的变化。方法:对66例确诊为hld患者出汗情况进行调查并行皮肤交感反应的检查。结果:66例hld患者有36例有出汗障碍;主要表现为四肢远端出汗减少(26例)合并代偿性局部出汗增多。

Results ① Plasma theophylline concentrations were in the range of 5~20 μg/mL in 668 patients of 908 patients (except one patient who committed suicide with theophylline), surpassing 20 μmL in 76 patients, and lower than 5μg/mL in 164 patients.

结果 ①除服茶碱自杀的1例病人外,其余908例病人中,首次检测茶碱血药浓度在5~20μg/mL范围内668例,超过20μg/mL者76例,低于5μg/mL者164例。

objective:to study the changes of dynamic electrocardiogram in patients with brain injury.methods:fifty-six patients with acute brain injury were recruited in this study.the glasgow coma scale, the initial computed tomogram and ambulatory electrocardiogram were performed in all subject.data were analyzed according to different place and severity of brain injury.results:ecg abnormalities were found in 32 patients out of 56 patients with acute head injury(57.14%).

目的:观察脑损伤患者的动态心电图改变,了解急性脑损伤致心电异常的特点及其与损伤部位和严重程度的关系。方法:选取我院急性脑损伤患者56例,经glasgow评分分型,脑ct确定损伤部位,并行24h动态心电图检查,观察急性脑损伤后心电异常的发生情况,并根据脑损伤部位和严重程度分组观察,以了解其心电异常的特点。

Methods 180 patients with uterine myoma peri-menopausal period were randomly divided into three groups. Patients in treatmentⅠgroup (n=100) were given Yiqizhuyu decoction. Patients in treatmentⅡgroup (n=40) were given Yiqizhuyu powder (twice a day, by taking medicine after mixing with water). The re was a discontinuation at menstruation. Patients in control group (n=40) were treated by cassia tuckahoe capsule (3 pills, thrice a day).

将180例围绝经期子宫肌瘤患者随机分为3组,治疗1组100例予益气逐瘀中药煎剂,日1剂,分2次口服;治疗2组40例予益气逐瘀中药颗粒,日1剂,分2次热水冲服;对照组40例予桂枝茯苓胶囊,每次3粒,每日3次口服。3组均经期停服,3个月为1个疗程,2个疗程后统计疗效。

Methods 180 patients with uterine myoma peri-menopausal period were randomly divided into three groups. Patients in treatmentⅠgroup (n=100) were given Yiqizhuyu decoction. Patients in treatmentⅡgroup (n=40) were given Yiqizhuyu powder (twice a day, by taking medicine after mixing with water). There was a discontinuation at menstruation. Patients in control group (n=40) were treated by cassia tuckahoe capsule (3 pills, thrice a day).

将180例围绝经期子宫肌瘤患者随机分为3组,治疗1组100例予益气逐瘀中药煎剂,日1剂,分2次口服;治疗2组40例予益气逐瘀中药颗粒,日1剂,分2次热水冲服;对照组40例予桂枝茯苓胶囊,每次3粒,每日3次口服。3组均经期停服,3个月为1个疗程,2个疗程后统计疗效。

Histopathologic examination demostrated cystic necrosis in 6 patients, mult ilocular cysticrenal cell carcinoma in 3, and unilocular cystic renal cell carcinoma in 3 patients. 11 patients have been followed up.l patient died of the disease at 9 months. 10 patients had no evidence of disease,whose suvival periods ranged 10 months to 10 years with an average of 3.5 years.

其中肾细胞癌囊性坏死型6例,单房囊肿性肾细胞癌3例,多房囊肿性肾细胞癌3例。11例获随访,其中1例以颅骨转移为首发症状者术后9个月死于肿瘤转移;10例存活至今,存活时间10个月—10年,平均3.5年。

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