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Patients had alien hand syndrome (11%), 17 patients had history of hypertention (54.83%) 16 patients had coronary artery heart disease (51.61%), 10 patients had diabetes mellitus (32.25%), 9 patients had history of cerebral infarction (29.03%), 17 patients had disorders of conciousness and mental (54.83%), 18 patients had language disorder (58.1%), 21 patients had disorders of limbs in different degrees (74.19%). MRI imaging of 22 patients showed previous cerebral infarction focuses (70.96%), 16 patients with leukoaraiosis (61%), 9 patients with angiostenosis (29%), stenosis was over 60% in 6 patients, and 7 patients showed cerebral microbleeding (22.58%). There were 34 focus of copus callusum infarctions in 31 patients.

异手综合征者3例(11%),高血压病史17例(54.83%),冠心病16例(51.61%),糖尿病10例(32.25%),脑梗死史者9例(29.03%),神志和精神异常的17例(54.83%),语言障碍的患者18例(58.1%),21例(74.19%)患者有不同程度肢体运动障碍。31例胼胝体梗死患者,共34处胼胝体梗死病灶,胼胝体梗死的患者合并其它部位陈旧性梗死灶22例(70.96%),伴有白质稀疏16例(61%),发现血管狭窄9例(29%,其中狭窄超过60%者6例),有7例(22.58%)伴有微出血。

The incidence of anxiety and depression in patients with FD was higher than that in healthy volunteers; The average extent of anxiety and depression of FD patients was significantly higher than that of healthy people (p 0.001). 2.The total scores of life events and the scores of negative life events in patients with FD was significantly higher than that of healthy group (p=0.014 and p 0.001), but the favorable life events scores was lower than healthy group's(p=0.001). 3. Eight healthy conceptions in the health-related quality of life of FD patients was significantly lower than that of healthy volunteers (p .001). 4. There was positive correlation among the symptom iterated integral, anxiety evaluation and depression evaluation of the FD patients (p0.001). 5. In the FD patients, there was no significant correlation between the evaluation of symptoms and life events. 6. In the FD patients, there was no significant correlation among symptoms evaluation, energy and body ache, and negative correlation among the other 6 health conceptions (p 0.05). 7. There was significant positive correlation among the total scores of life events、negative life events scores and anxiety evaluation of the FD patients(p.01),and also with depression evaluation(p.05),there was no significant correlation among the favorable life events scores with anxiety and depression evaluation both. 8. There was negative correlation among anxiety evaluation, depression evaluation and 8 health conceptions of the FD patients (p 0.001). 9. There existed negative correlation respectively among the total scores of life events and negative life events scores with 6 health conceptions of the FD patients (p 0.05) and 7 health conceptions of the FD patients (p 0.05), there was no significant correlation among the favorable life events scores and the health-related quality of life of FD patients.

结果:1、FD患者焦虑、抑郁的发生率明显高于健康对照组(p.005),平均焦虑、抑郁程度高于对照组(p.001)。2、FD患者经历的生活事件总值(p=0.014)和负性生活事件值(p.001)明显高于健康对照组,正性生活事件值低于对照组(p=0.001)。3、FD患者的生活质量在8个健康概念上均明显比健康人差(p.001)。4、FD患者的症状积分与焦虑评分、抑郁评分呈正相关(p.001)。5、FD患者的症状积分与生活事件值均无相关性。6、FD患者症状积分与活力、躯体疼痛之间无明显相关性,与其余6项健康概念均呈负相关(p.05)。7、FD患者的生活事件总值、负性生活事件值与焦虑评分均显著正相关(p.01),与抑郁评分也均呈正相关(p.05),正性生活事件值与焦虑和抑郁水平均无相关性。8、FD患者焦虑评分、抑郁评分与8项健康概念均呈负相关(p.001)。9、FD患者生活事件总值和负性生活事件值分别与生活质量8项健康概念中的6项和7项呈负相关(p.05),正性生活事件值与生活质量无关。

The malignant tumors included osteogenic osteosarcoma,metastasis tumor(six patients,two with pathologic fractures),chondrosarcoma,malignant fibrous histiocytoma (three patients,one with pathologic fracture),fibrosarcoma,and solitary myeloma.all patients received limb savage procedure with custom knee prosthesis including sevnteen cases of hinge joint and twentyone cases of posterior stability joints.Results One of nine patients with benign tumors was lost for followedup,one patient died of unrelated disease,the remained patients have excellent function in five patients,good function in one case,and one poor according to the Enneking evaluating system.the limb salvage rate was 100%.Seven patients were lost for followedup in twentynine of malignant tumors,two patient with malignant fibrous histiocytoma received amputation due to local recurrence nine months postoperatively.Ten patients had excellent function,four good and six poor among the followedup patients.The type of prosthesis in six of all patients with poor function was hinge.

结果 9 例良性肿瘤患者1 例失访,1 例死于其他不相关疾病,其余7 例病人随访时膝关节功能按Enneking制定的标准进行评定,优5 例,良1 例,差1 例,保肢成功率为100%;29 例恶性骨肿瘤患者,骨肉瘤患者失访7 例,2 例患者术后局部复发,行截肢术;其余20 例患者生存期间膝关节功能优10 例,良4 例,差6 例。7 例效果评价差的病人为有6 例为铰链式膝关节假体。

Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%),Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%)恶性淋巴瘤症状, 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%)恶性淋巴瘤分期,Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Results In the 121 patients, 47 patients(39%) were accommodative failure, 66 patients(55%) were lag of accommodation checking with FCC, 53 patients (43.8%) were uncorrected presbyopia, 65 patients (53.7%) were break up time of tear film<10s, 87 patients (71.8%) couldn't been corrected the refraction errors or the correction of refractive errors was unsatisfied, 24 patients(19.8%) were esophoria, 17 patients (14%) were exophoria, 8 patients (7%) were anisometropia.

结果 121例患者中,调节灵活性明显降低者47例,占39%;FCC检查调节滞后者66例,占55%;未矫正老视者53例,占43.8%;泪膜破裂时间<10s者65例,占53.7%;屈光矫正不足或未予矫正者87例,占71.8%;内隐斜者24例,占19.8%;外隐斜者17例,占14%;屈光参差者8例,占7%。

Results Histopathological examination showed that 8 patients had cervical intra-epithelial neoplasia,including 4 patients with CIN grade Ⅰ,3 patients with CIN grade Ⅱ,1 patients with grade Ⅲ and 1 patients with carcinoma in situ of cervix;1 patients with invasive carcinoma;113 patients with chronic cervicitis;80 patients had polypi;15 patients had HPV infection.

结果 病理确诊宫颈不典型增生(CINⅠ~Ⅲ8例,其中CINⅠ4例,CINⅡ 3例,CINⅢ 1例;宫颈原位癌1例、宫颈浸润癌1例、慢性宫颈炎113例、宫颈息肉80例及HPV感染者15例。

Results Histopathological examination showed that 8 patients had cervical intra-epithelial neoplasia,including 4 patients with CIN grade Ⅰ,3 patients with CIN grade Ⅱ,1 patients with grade Ⅲ and 1 patients with carcinoma in situ of cervix;1 patients with invasive carcinoma;113 patients with chronic cervicitis;80 patients had polypi;15 patients had HPV infection.

结果 病理确诊为宫颈不典型增生8例,其中CINⅠ4例,CINⅡ 3例,CINⅢ 1例;宫颈原位癌1例、宫颈浸润癌1例、慢性宫颈炎113例、宫颈息肉80例及HPV感染者15例。

Material and Methods:From March,2008 to January,2009,250 patients(146 Males and 104 Females,ranged from 18 to 82 years old,mean age was 48 years old) enrolled in the First Affiliated Hospital of Kunming Medical College were performed dual energy scan(Group A,200 patients) and Neuro-DSA scan(Group B,50 patients) using DSCT.The patients were randomly divided into Group A and Group B.Regarding to the justification of scan protocol,100 patients in Group A were selected as sub-group to explore the scan protocol.The image quality Was analyzed both in four categories(4.0/60、4.5/60、4.0/70、4.5/70) of flow rate and total amount of contrast-enhanced material and in three categories(100—150HU、150—200HU、200-250HU) of CT value of left common carotid artery.The comparison of two scan approach was based on image quality,radiation does, postprocessing methods,time of scanning and subtraction and data storage amount.To validate the diagnostic capability of DE-CTA virtual unenhanced images,100 patients in Group A were undergoing head scan both in routine non-contrast program and DE-CTA virtual unenhanced program.Mean CT values,signal-to-noise ratio,image quality,sensitivity of lesion identification,and radiation does were applied to comparison.According to diagnostic results of dual energy of cerebral arterial angiography,62 patients out of 200 patients in Group A were confirmed with cerebral vessel lesions,the results were complied with DSA findings(the time between the two methods were within 1 week).

材料与方法收集2008年3月到2009年1月间在昆明医学院第一附属医院行DSCT CTA检查者250例(男性146例,女性104例,年龄范围18-82岁,平均48岁),随机分为A、B两组,A组200例行双能量头颅CTA扫描;B组50例行Neuro-DSA扫描。A组前100例按对比剂不同流率和总量分为4组(4.0/60、4.5/60、4.0/70、4.5/70)对图像质量比较;按触发时左颈总动脉内平均CT位分3组(100—150HU、150—200HU、200-250HU),比较图像质量的差异;对A、B两组血管图像质量、辐射剂量、后处理的方法、扫描和后处理时间及数据的容量进行比较分析;A组中前100例行常规与DE-CTA虚拟平扫的平均CT值、信号噪声比、图像质量、病灶显示情况、辐射剂量的比较分析;A组中行DSA检查62例(两种方法间隔时间均1周内),比较两种检查方法诊断结果是否符合,并对其中24例动脉瘤行动脉瘤部位、数目、形态、瘤颈显示程度、瘤颈大小及瘤体长径和短径的比较研究。

No Ⅲ° atrioventricular conduction block happened, 9 patients developed right bundle branch block, and 2 patients showed junctional rhythm. Two patients with perimembranous extending outlet were repaired because of residual shunt(0.4cm,0.3cm) on the anterosuperior rim of defect. One patient with trivial residual shunt(0.15cm) on the posteroinferior rim of defect was found closed spontaneously six months later. Tricuspid valve was incised in 10 patients of VSD sextending outlet,8 patients vertical to the valve ring,2 patients parallel to the valve ring. Moderate tricuspid valve regurgitation was found in 1 patient, mild in 5 patients, trivial in 4 patients. No one aggravated. One patient complicated with pericardial effusion.

无Ⅲ°房室传导阻滞发生,9例发生右束支传导阻滞,2例结性心律。2例膜周偏流出道型VSD患者因前上缘残余分流分别为0.4cm和0.3cm,再次手术修补;1例后下缘残留细束样分流,直径0.15cm,随访6个月后自愈;10例膜周偏流出道型VSD患者剪开三尖瓣,8例垂直瓣环,2例平行瓣环;1例三尖瓣中度反流,随访无加重;5例轻度反流,4例轻微反流,随访均无加重;1例心包积液;1例再次进入手术室止血。

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