查询词典 pathway

This study aims at the expression of Wnt signaling pathway inhibitor FrpHE and DKK-1 induced by ectogenous factor.

本课题的目的在于研究外源性因素对Wnt通路抑制剂FrpHE和DKK-1的诱导表达，我们选择抗癌药物p53及化疗药阿霉素、羟喜树碱、顺铂作为外源性诱导剂，以期弄清Wnt通路及其抑制剂FrpHE和DKK-1是否能够被p53和化疗药这两类药物所调节。

ABSTRACT Hairy and Enhancer-of-split-type protein 1 (Hes1) is a main effecter of the Notch pathway and acts as a differentiation repressor and/or as a pro-expansion factor during the pancreatic development.

由于人们尚未找到胰腺干细胞的特异性标志，因而给胰腺干细胞的分离纯化及其特性的研究带来了极大的困难。来自hes1-/-敲除小鼠的研究提示，Hes1作为Notch信号通路的一个关键分子，在胰腺发育过程中扮演着扩增促进因子或分化抑制因子的角色，因而有可能用作胰腺干细胞的备选标志分子，但这一推论缺乏直接的证据。

In all likelihood, a variety of insults to the ear can lead to endolymphatic hydrops as their common final pathway, thereby producing symptoms akin to those of Meniérè's disease.

大多情况下，随着他们通常的方式各种感染耳朵的方式可能导致此种情况。因此同类症状会产生梅尼埃氏病。

Meanwhile, we found the colocalization of mRabL5 with WGA-positive endosome by immunofluorescence assay, which further demonstrated that mRabL5 may cycle between cytolsol and membrane system to facilitate endocytosis pathway.

利用该抗体，我们检测到mRabL5是一个广谱表达的蛋白，与TGN共定位，作为一种小G蛋白，循环于膜系统和胞质之间，参与内吞途径。

The wingless signaling pathway causes the engrailed gene to be expressed.

同源异型基因则决定了每个体节独特的分化进程。

Analysis of five other epigenetically repressed genes indicates that Ras directs the silencing of multiple unrelated genes through a largely common pathway.

分析另外5个表观抑制基因显示Ras通过一个主要的共有通路指导多相关基因的沉寂。

AIM: To observe the effects of total flavones of epimedium on experimental myocardial ischemia through intravenous injection and gastroenter-administration pathway.

目的：观察淫羊藿总黄酮静脉注射和胃肠道给药途径对实验性心肌缺血的影响。

Take together, esculetin presented antiproliferation effect involving modulating the expression of cell cycle related proteins and the MAPK signal pathway.

综合以上结果esculetin抑制细胞增生乃藉Ras/MAPK以及Akt这两条讯息传递路径而影响调节细胞周期分子的表现。

The results suggested that AC-cAMP-PDE pathway in cerebellum did not participate in regulating the anesthetic action, but perhaps correlated with ethological changes (such as behavior mis match and orientating function handicapped) during recovery period.

4临床相关剂量的噻拉唑和QFM合剂对大鼠大脑皮质、海马、脑干和小脑的PDE活性无影响，结果说明，大脑皮质、海马、脑干和小脑AC-cAMP-PDE信息传递系统对噻拉唑和QFM合剂麻醉作用的调控不是通过PDE对cAMP的降解作用，而是通过其它途径（如通过调节AC的活性影响cAMP的生成环节）来调控cAMP的产量实现的。

Because the patients′platelets had normal reaction to low concentration (another TXA〓-dependent agent) and these indicated that the common post-receptor pathway of signal transduction was normal when the excitory stimulus combined with the patients′platelets.

由于患者对低浓度胶原(亦为TXA〓依赖的诱聚剂)反应正常，说明患者血小板在与活化信号结合后，其共同的受体后信号传导道路是正常的。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。