查询词典 pathology

Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer

采用免疫组织化学染色方法检测88例结肠癌组织中Livin，Caspase3 及MTA1的表达情况。结果（1）结肠癌组织中Livin的阳性表达率显著高于癌旁组织，且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（2）结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织，且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。（3）结肠癌组织中MTA1的阳性表达率显著高于癌旁组织，且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（4）Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论（1）Livin在结肠癌组织中过表达，它可能是促进结肠癌发生的重要因素之一。（2）Caspase3蛋白在结肠癌组织中表达被抑制而降低，且与Livin的表达呈负相关。因此，抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。（3）MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。

The positive expression both of p14ARF and mtp53 protein in NSCLC tissues were significantly different from that in nonmal lung tissues and tissues adjacent to the cancer (P.01).The expression of p14ARF protein was correlated with pathological degree（P＜0.01）,but it was uncorrelated with pathological staging,lymphaden metabasis and vessel invasion(P＞0.05).The expression of mtp53 protein was correlated with clinical pathology staging,pathological degree and vessel invasion(P＜0.05 or P＜0.01),but it was uncorrelated with lymphaden metabasis(P＞0.05).(2) The coexpression of p14ARF and mtp53 was 36.7％,their consistency was 38.8％,but the expression of p14ARF protein were negatively correlated with the expression of mtp53 protein(r=-0.3553,P＜0.001).Conclusion The results suggest that the decrease of p14ARF and the increase of mtp53 protein may play an important role in the genesis and development of NSCLC.

结果 (1)在正常肺组织、癌旁组织和NSCLC中p14ARF蛋白的阳性表达率分别为93.3%、83.3%、55.1%，mtp53蛋白的阳性表达率分别为6.7%、44.4%、79.6%；p14ARF蛋白和mtp53蛋白在NSCLC中的表达与正常肺组织和癌旁组织比较均有显著性差异(P＜0.01)；p14ARF蛋白表达与临床病理分期、有无淋巴结转移、有无脉管浸润无关(P＞0.05)，而与病理分化程度有关（P＜0.01）；mtp53蛋白表达与临床病理分期、病理分化程度(P＜0.01)及有无脉管浸润(P＜0.05)有关，而与有无淋巴结转移无关(P＞0.05)；(2)在NSCLC中，pl4ARF与mtp53蛋白共表达为36.7％，一致性为38.8％，二者表达呈负相关(r=-0.3553，P＜0.001)。

Finally, a biopsy was done and the pathology revealed osteonecrosis of the third left metatarsal bone.

最后经由切片证实是第三跖骨的骨坏死。

1Team 15, Cadet Brigade, School of Stomatology, 2Department of Pathology, School of Basic Medicine, Fourth Miliary Medical University, Xian 710033, China

作者：张潇何芙蓉王璐黄高昇作者单位：第四军医大学： 1口腔系学员15队， 2病理学教研室，陕西西安 710033

This is the website of the Research Institute of Molecular Pathology.

这是分子病理学研究所的网站。

They were also regarded as diseases or part of the morbid pathology of functions.

这些函数不过被看作是一种变态或是函数的不健康部分。

However, these approaches lead to increased pathology costs and morbidity, he said.

然而，这些方法增加了医疗成本和并发症的发生。

TLF and FYK can resume the pathology and morphallaxis of oviduct in varying degrees, reduce IL-2、IL-6 both in serum and oviduct, and so raise the pregnant rate.

通络助孕方和对照药能不同程度恢复模型大鼠输卵管病理形态学改变，降低血清和局部输卵管组织中IL-2、IL-6水平，提高受孕率。

Methods: Mixed bacterium was used for making salpingitis caused sterility rats model, treated by different doses of TLF contrasted with Fuyankang , the pathology and morphallaxis of oviduct with Light and Transmission electron microscope was observed, the content of IL-2、IL-6 in serum and oviduct was checked by ELISA method, pregnant results also was traced.

用"混合菌接种法"制作大鼠慢性输卵管炎性不孕动物模型，以不同剂量的通络助孕方和对照药妇炎康对模型大鼠治疗后，观察光镜和电镜下输卵管病理形态学改变情况，用ELISA法检测血清和输卵管组织中IL-2、IL-6含量，并观察大鼠受孕情况。

Purpose: To explore and make big rats model of sterility caused by chronic salpingitis, observe the effect of Tongluozhuyunfang on the pathology and morphallaxis of oviduct, interleukin IL-2、IL-6 in serum and oviduct, and trace the rats pregnant rate for exploring its curative mechanism.

中文题名通络助孕方对炎性不孕大鼠输卵管作用的实验研究副题名外文题名 Experimental study on mechanisms of Tongluozhuyunfang treated rats salpingitis sterility 论文作者赵广兴导师马宝璋袁家麟教授学科专业中医妇科学研究领域\研究方向学位级别博士学位授予单位黑龙江中医药大学学位授予日期2002 论文页码总数63页关键词不孕症通络助孕方输卵管炎馆藏号BSLW /2003 /R271.1 /4 目的：探索制作慢性炎症所致不孕大鼠模型，探讨中药通络助孕方对慢性炎性不孕大鼠输卵管病理形态学、细胞因子IL-2、IL-6和受孕率的影响及其疗效机理。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。