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Because the dimeric form is the active form to exert its biological activities, many trials failed to express TGF β s in prokaryotic systems because of their complex folding manner and disulfide patterns. In 1991 Cerletti and coworkers from Ciba-Geigy Corporation in Switzerland successfully finished the functional expression of human TGF β 2 in bacteria, but the details are protected by the patent.

由于双体是其发挥生物活性的形式，TGF β复杂的折叠方式和二硫键配对使其早期原核基因工程研究都以失败而告终。1991年，瑞士Ciba-Geigy公司的Cerletti等成功完成了人TGFβ2基因的细菌表达，但其技术细节被专利加以保护。

Article 4 (1) Sub-paragraph of paragraph (3) of Article 12 of the Agreement shall be deleted and replaced by the following:" payments of any kind received as a consideration for the use of, or the right to use, any copyright of literary, artistic or scientific work, including cinematograph films, and films or tapes for radio or television broadcasting, or any patent, trademark, design or model, plan, secret formula or process, or for information concerning industrial, commercial or scientific experience; and".

二、在协定第十三条第三款中，取消下列文字："包括使用或有权使用有关工业、商业、科学经验的情报，"。一、取消协定第二十三条第三款、第四款和第五款，由下列条款代替

Circuity of Action is a long-standing problem in patent invalidity declaratory judgmentlitigation in China.

我国专利无效诉讼领域长期存在"循环诉讼"的问题。

At present, Beijing Huayi puts its main strength on China City Blue Page, a Beijing-based project aiming at whole China. In addition, we have successfully applied patent for China City Blue Page Public Information Free Inquiry Machine and registered China City Blue Page brand. Now Beijing Huayi is a forerunner in IT industry in China.

目前我公司主营项目《中国城市蓝页》立足北京积极向全国拓展，申请了"中国城市蓝页公众信息免费查询机"专利，同时注册了"中国城市蓝页"商标，填补我国目前IT行业一项空白。

Patent of chilling effects clearinghouse is maintained by University of Maine, School of Law.

冷冻效果交易所研究主题中的专利研究是由缅因州大学法学院主办的。

And though poor Amy slept with a patent clothespin pinch ing it, she couldn't attain the Grecian effect she so much desired.

尽管可怜的艾米在睡觉时用一只特制的衣服夹子夹住它，也无法达到她所要求的高鼻子的目的。

For, when she was a baby Jo had accidentally dropped her into the coal-hod and permanently flattened that feature, and though poor Amy slept with a patent clothespin pinching it, she couldn't attain the Grecian effect she so much desired.

因为，在她还是婴儿时，乔不小心把她掉进煤筐里，把鼻子摔扁了，造成了永久的破相。尽管可怜的艾米在睡觉时用一只特制的衣服夹子夹住它，也无法达到她所要求的高鼻子的目的。

For, when she was a baby Jo had accidentally dropped her into the coal-hod and permanently flattened that feature, and though poor Amy slept w IT h a patent clothespin pinching IT , she couldnt attain the Grecian effect she so much desired.

因为，在她还是婴儿时，乔不小心把她掉进煤筐里，把鼻子摔扁了，造成了永久的破相。尽管可怜的艾米在睡觉时用一只特制的衣服夹子夹住它，也无法达到她所要求的高鼻子的目的。

For, when she was a baby Jo had accidentally dropped her into the coal-hod and permanently flattened that feature, and though poor Amy slept with a patent clothespin pinching it, she couldnt attain the Grecian effect she so much desired.

因为，在她还是婴儿时，乔不小心把她掉进煤筐里，把鼻子摔扁了，造成了永久的破相。尽管可怜的艾米在睡觉时用一只特制的衣服夹子夹住它，也无法达到她所要求的高鼻子的目的。

TCM clinical treatment consists of TCM examination (Chinese medical four diagnostics and modern imaging, experimental diagnosis), prescription plus Chinese medicine tablets or Chinese patent medicine oral administration treatment, acupuncture treatment, massage treatment, coaptation diaplasis treatment, external medicine treatment, beauty treatment and remaining in hospital for observation treatment.

中医临床治病，包括中医诊病（中医四诊和现代影像、实验诊断），开处方配中药饮片或中成药内服治疗、针灸治疗、推拿治疗、接骨复位治疗、外药治疗、美容治疗、留医观察治疗。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。