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In order to study the ability to the thrombus formation,41 patients with essential hypertension and 34 patients with normotension were investigated.The plasma level of fibrinogen and tissue-type plasminogen activator antigen and plasminogen activator inhibitor 1(PAI-1)antigen were determined.

为了解高血压病人的血栓形成倾向，我们随机选取了41例高血压病人及34例正常血压者，分别观察了他们的纤维蛋白原及血浆组织型纤溶酶原激活物抗原及纤溶酶原激活物抑制物-1(PAI-1)的含量。

objective to invetigate the variations of plasminogen activator inhibitor-1(pai-1) and tissue-type plsminogen activator in patients with diabetic nephropathy.

目的 探讨2型糖尿病（t2dm）患者血浆纤溶酶原激活物抑制物（pai-1）和组织型纤溶酶原激活物活性水平的变化及其与糖尿病肾病的关系。

Plasminogen activator inhibitor-1 (PAI-1) is a physiological inhibitor of tissue-type plasminogen activator and urokinase-type plasminogen activator .

纤溶酶原激活物抑制因子-1（PAI-1）是组织型纤溶酶原激活物和尿型溶酶原激活物的生理性抑制因子。

Plasminogen activator inhibitor-1 (PAI-1) is a physiological inhibitor of tissue-type plasminogen activator t-PA...

纤溶酶原激活物抑制因子-1（PAI-1）是组织型纤溶酶原激活物和尿型溶酶原激活物的生理性抑制因子。

Role of endothelial function and inflammation in patients with cardiovascular risk factors, with and without a history of myocardial infarction;Comparison of gated blood pool SPECT and multidetector row computed tomography for measurements of left ventricular volumes and ejection fraction in patients with atypical chest pain: Validation with radionuclide ventriculography;Plasma adiponectin, T94G gene polymorphism and PAI-1 in patients with and without hypertension;Prognostic value of myocardial perfusion imaging in symptomatic and asymptomatic patients after percutaneous coronary intervention;Impact of early initiation of intravenous therapy for acute decompeusated heart failure on outcomes in ADHERE……

文章摘要：内皮功能和炎症在有或无心肌梗死病史的具有心血管危险因素患者中的作用；门控血池SPECT和多层螺旋CT对于测量不典型胸痛患者左室容积和射血分数的比较：以放射性核素心室造影检查进行验证；有或无高血压的患者的血浆脂联素、T94G基因多态性和PAI-1；心肌灌注成像对经皮冠状动脉介入后有症状和无症状患者的预后评估价值；ADHERE中早期开始静脉用药治疗急性失代偿性心力衰竭对预后的影响

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

The levels of PAI-1 protein and mRNA were analyzed with Western blotting analysis and RT-PCR respectively.

采用MTT和流式细胞仪检测细胞增殖，Western blotting和RT-PCR法检测PAI-1的表达水平。

UPA and PAT-1 might be the target genes of Smad4. It was much more significant to investigate the expression of Smad4 uPA and PAI-1 combinedly in colorectal carcinoma than to investigate the expression of only one of them.

联合检测大肠癌中 Smad4、uPA和PAI-1蛋白的表达情况，相比单一检测一种蛋白而言，对于评估大肠癌的发生、发展及预后更具有意义。

PAI-3 was expressed in the human skin and mainly located in the superficial,more differentiatied layers of the epidermis,and was incorporated into the cornified envelope of terminally differentiated keratiocytes.

1、PAI-3 在人皮肤表皮组织中表达，且主要位于分化程度较高的表皮KC 中，其存在终末分化KCs 角质壳中。

PAI-3 was incorporated into the cornified envelope of terminally differentiated keratiocytes.

PAI-3 存在终末分化KCs 角质壳中。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。