查询词典 pai-hua

The four components of uPA system could be synthesized and secreted by all the four cell lines, existed in duplet or triplet form (uPA/PAI-1,uPA/PAI-2,uPA/uPAR,uPA/PAI-1/uPAR and uPA/PAI-2/uPAR). The expression of uPA system were not in concomitance with the malignance of the cell lines.Subject headings urokinase; carcinoma, non-small-cell lung; cells,cultured

此4株细胞中均能合成与分泌uPA系统的4种主要成分，各因子以二联及三联复合物(uPA/PAI-1、uPA/PAI-2、uPA/uPAR、uPA/PAI-1/uPAR、uPA/PAI-2/uPAR)的形式存在；uPA系统的表达与这4种细胞的恶性程度并不一致。

FPG,FINS,TG,TC,LDL-C of Model group were increased,ISI were decreased . The expression of PAI-1mRNA of adipose tissues was increased significantly (.2)Compairing with model group,the berberine and taurine group and combine group could significantly increase insulin sensitivity, decrease the expression of PAI-1mRNA in epiploon adipose tissue. The parameters mentioned above in combine group was better than other groups.

与正常组比较，模型组体重增加，血清 FPG、FINS、TG、TC 、LDL-C 升高，ISI 降低，血清中 FFA 浓度增加，内脏脂肪细胞肥大，脂肪组织中 PAI-1 mRNA 表达显著增加；(2)与模型组比，联合组、黄连素组、牛磺酸组、二甲双胍组均出现 ISI 升高和 PAI-1mRNA 表达减少，二者的协同作用优于单独作用，并优于二甲双胍组。

In this study,the expression and role of PAI-3 in the epithelization of human skin,including normal adult human skin,cultured differentiated keratinocytes and the development of human embryo,were observed,so as to elucidate the possible role of PAI-3 in the epithelization of skin and provide the experimental base for further studying the mechanism in epithelization of skin and all kinds of skin diseases.

本实验旨在研究正常成人皮肤组织及培养分化KC 中和胚胎生长发育过程表皮KC 中的PAI-3 的表达及作用，希望有助于阐明PAI-3 在皮肤上皮化中的功能，为进一步研究PAI-3 在皮肤上皮化中的机制及各种皮肤疾病提供实验基础。

Results: Expression of PAI-1, TIMP-1 and FN in kidney of diabetic rats began to increase in the second week of diabetes; PAI-1 and TIMP-1 mainly expressed in intracytoplasm of renal tubular epithelial cells, while FN mainly expressed in renal tubule matrix and glomerului; Their expression showed a tendency of increasing along with the progression of diabetes.

结果：PAI-1、TIMP-1及FN表达从糖尿病2周起较正常对照组明显增多(P.01)，PAI-1和TIMP-1阳性表达主要位于肾小管上皮细胞胞浆内，FN阳性表达主要位于肾小管间质和肾小球，且随着糖尿病进展有逐渐增加的趋势。

WhenPAI-1 level is lower than u-PA level,the tumor cannot protect itself againstthe excess proteolysis of u-PA.Furthermore,high PAI-1 may be associatedwith migration and reimplantation of cancer cells.This hypothesis is supportedby the following observation.

同时基于上述原因，u-PA和PAI-1高表达者，发生周围淋巴结转移的阳性率高于u-PA和PAI-1低表达者。u-PA、PAI-1阳性表达与肝门胆管癌的预后相关，u-PA及PAI-1呈阳性表达者，其生存期较阴性及弱阳性表达者明显减低。

Methods The level of serum and urinary tissue-type plasminogen activator and plasminogen activator inhibitor-1 (PAT-1) were measured in 38 patients with chronic glomerulonephritis, 28 patients with nephropathy syndrome, 36 patients with chronic renal failure and 20 healthy subjects by means of enzyme-linked immunosorbent assary. The relationship among urinary t-PA, PAI-l and serum t-PA, PAT-1, urinary protein, serum creatinine were also observed. Results Levels of serum t-PA, PAI-1 in chronic kidney diseases increased remarkably compared with control group.

选择38例慢性肾小球肾炎，28例肾病综合征，36例非透析治疗的慢性肾功能不全和20例正常对照作为研究对象，应用ELISA法检测血清和尿液中组织型纤溶酶原激活剂和纤溶酶原激活物抑制剂－1(PAI-1)的浓度，同时分析尿中t-PA和PAI-1的水平与血t-PA、PAI-1、血肌酐和24h尿蛋白总量之间相关性。

PAI-3 expression increased in the processes ofKCs differentiation. PAI-3 can incorporate into the cornified envelope andmay promote the differentiation ofkeratinocytes.

人表皮KC分化过程中， PAI-3的表达随着分化的增加而增加， PAI-3存在终末分化KCs角质壳蛋白中，表明PAI-3参与KC分化的作用。

An amount increase ofPAI-3 andK10 was observed after theKCswere cultured for48 h in high calcium medium,butat72 h the exprssion ofPAI-3 decreased. The positive stain ofPAI-3 wasmainly localized in perinuclearmembrane in lowcalcium medium and in cytoplasm in high calcium medium. PAI-3 was incorporated into cornified envelope ofterminally differentiated keratinocytes.

结果 高Ca2+浓度下培养24 h后，分化标记物K10弱阳性表达， PAI-3呈阳性表达；培养48 h后， K10强阳性表达，而PAI-3的阳性表达明显增加， 72 h后，表达开始降低，在低Ca2+浓度下阳性染色主要位于细胞核膜周围而高Ca2+浓度下主要位于细胞质，同时， PAI-3存在终末分化KCs角质壳中。

Simultaneously 15 samples of normal nephric tissue were used as control.The sections from these samples were subjected to immunohistochemical analysis with antibodies directly against uPA and PAI-1 by LSAB method. In this study we adopt semiquantitative analysis to determined the expression of these molecules , and utilized the relevant data processing and statistical analysis to evaluate the correlation between their expression and the clinicopathological features of RCC.Results: 1. The positive rate of uPA and PAI-1 of uPA in RCC were 72%(36/50)and 56%(28/50), respectively.But in control group there was nearly

正常肾组织标本中几乎无阳性染色。2、uPA表达水平与患者年龄、性别、肿瘤病理分级无关(均P＞0.05)，与T分期、淋巴结转移有明显的相关性(r=0.684，P＜0.05；r=0.789，P＜0.05)，uPA高表达多见于T_(3-4)、有转移的RCC.3、PAI-1的表达水平与患者年龄、性别、肿瘤病理分级和T分期无关(P＞0.05)，与淋巴结转移有明显的相关性(r=0.800，P＜0.05)，PAI-1高表达多见有转移的RCC.4、对uPA和PAI-1行相关性检验，uPA在RCC中的表达与PAI-1的表达呈明显正相关(r=0.168，P＜0.05)。5、uPA和PAI-1的表达与淋巴结转移的关系以Logistic回归法进行分析，结果显示uPA与区域淋巴结转移密切相关，uPA是淋巴转移的危险因子(RR=2.718，95％CI=1.150～7.170，P=0.024)，PAI-1则不是淋巴转移的危险因子(RR=1.599，95％CI=0.624～4.102，P=0.328)。

objective to study the changes of t-pa and t-pa inhibitorduring the acute stage of cor pulmonale.methods to measure the plasmatic activity of t-pa and pai by chrom-substrate in60cases of cor pulmonale,compared with the corresponding index of55cases in the control group.results pai was significantly higher in acute stage than in remission stage of corpulmonale,and t-pa was lower in remission stage than in acute stage.the difference was significant（p.01）.conclusion the unbalance between t-pa and pai can promote the formation of micro-thrombus and further exacerbate high pulmonary pressure.

目的 探讨血浆组织型纤溶酶原激活物及t-pa抑制物在肺心病急性加重期的变化。方法用发色底物法测定60例肺心病急性加重期的血浆t-pa及pai的活性，并与对照组55例肺心病缓解期的相应指标作比较。结果肺心病急性加重期患者pai显著高于肺心病缓解期，而t-pa低于肺心病缓解期，其差异具有非常显著性（p.01）。结论 t-pa及pai关系失衡，有助于动脉内微血栓形成，促进或加重肺动脉高压的形成。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。