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The results show that the hyperalgesia of OFQ and its antagonization on AA in PAG are dose-related. OFQ in PAG decreases the enhancing effect on AA induced by ohlnefentanyl, a selective μreceptor agonist.

结果表明:PAG内微量注射OFQ可使大鼠痛阈降低,并明显对抗针刺镇痛;另外还发现,OFQ在PAG内还可以对抗μ受体激动剂羟甲芬太尼加强针刺镇痛的效应。

The activation of NRM neurons by electroaeupuncture was eliminated after decerebration at superior colliculus level, indicating that this effect of EA depends mainly on the supra-midbrain structure. Furthermore, all treatments including AR isolation, disconnection of #beta#-endorphinergic tract and micrpinjection of naloxone or anti-#beta#-endorphin serum into PAG, would make the effect of EA disappear. Thus, it is the #beta#-endorphinergic pathway between AR and PAG-NRM system that mediates the major excitatory effect of EA on NRM.

检验AR至 PAG-NRM的神经通路在电针效应中的作用:实验显示上丘水平去大脑后,电针兴奋NRM的效应完全消失,表明此效应主要依赖中脑以上结构实现,进一步分别用Halfisz氏刀游离AR、切断AR至PAG的β-End能束、PAG内注射纳洛酮或抗β-End血清后,也使电针效应基本上完全消失,说明电针使NRM神经元兴奋的效应,主要通过AR与PAG-NRM间的β-End能神经通路实现。

PAG-DRP with properties of spatial and temporal summation propagates decre- mentally along the dorsal root and is inhibited by picrotoxin.

PAG-DRP 具有空间和时间总和性质,沿背根作电紧张性扩布,且能被 GABA 能拮抗剂印防己毒素所抑制。

A large number of neurons in the PAG of the audiogenic seizures-prone rats participated in the process of the audiogenic seizures.

听源性惊厥易感大鼠PAG内大量神经元参与了听源性惊厥发作过程。

The COD value in the dorsal and dorsolateral subdivisions of the PAG in the kindled audiogenic seizures-prone rats were significantly higher than that in the naive audiogenc seizures-prone rats.

用光镜观察PAG各节段各亚区切片上突触密度的变化,以期在光镜水平上了解PAG在惊厥状态下超微结构的某些变化。

Results The value of corrected optical density of the synaptophysin P38 immunoreactivity in the PAG of the naive and kindled audiogenic seizures-prone rats were significantly higher than that of the normal Wistar rats.

据此,本实验以P38免疫细胞化学反应的强度为指标,间接地对听源性惊厥易感大鼠(P77PMC)中脑导水管周围灰质(periaqueductal gray, PAG)各亚区突触的分布情况进行了研究。

Methods The neuronalstaining method and the immunocytochemical method were used to identify the Fos-postive neurons in the PAG of the audiogenic seizures-prone rats(P77PMC) after audiogenic seizures.

用神经细胞染色和免疫细胞化学技术,观察听源性惊厥发作后易感大鼠(P77PMC)PAG内即早基因c-fos的表达情况。

The results suggest that habenula may serve as a relay in the descending pathway of analgesia from nucleus accumbens to PAG, using ME in habenula and ME and GABA in PAG as neurotransmitters.

结果提示从伏核下行的神经通路可能经缰核中继到达PAG,在PAG内GABA也参与镇痛信息的传递。

Thus, the analgesic effect of morphine injected into PAG was significantly attenuated by β-EP AS injected into the nucleus accumbens, and vice versa. This antagonistic effect was totally abolished by lesioning of the ARH. Moreover the analgesic effect of morphine injected into nucleus accumbens could be blocked byβ-EP AS administered te amygdala or habenula.

在PAG内注射吗啡产生的镇痛作用可被伏核内注射β-EP抗体所削弱,损毁家兔的ARH后这一对抗效应基本消失;在伏核内注射吗啡产生的镇痛作用可被PAG内注射β-EP抗体所对抗,损毁ARH后上述对抗效应基本消失;伏核内注射吗啡产生的镇痛作用亦可被杏仁核内或缰核内注射β-EP抗体所阻断。

It is possible that morphine applied to VLO depresses the GABAergic interneuronal activities that tonically inhibits the VLO output neurons projecting to PAG, leading to activation of the PAG-brainstem descending inhibitory system which depresses the nociceptive inputs at the spinal cord level.

可能是:吗啡供给到VLO通过抑制GABA能中间神经元对VLO-PAG投射神经元的抑制作用,这种去抑制效应,可能加强脑干下行抑制系统的活动,在脊髓水平抑制伤害感受性输入。

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相关中文对照歌词
Himig Ng Pag-Ibig
Pag Ayaw Mo Na
Pag-Ibig
Iingatan Ko (Ang Pag-Ibig Mo)
Ang Pag-Ibig Mo
Sa Duyan Ng Pag-Ibig
Sa Aking Pag-Iisa
Pag-Ibig
Pag-Agos
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