查询词典 p-bromoacetanilide

Experimental results show that, compared with the normal pulse, the wiry pulse has an increased PWV(P＜0.01 or P＜0.05), the thready pulse has a decreased PWV(P＜0.05),but the PWV of the smooth pulse is not significantly different from the normal's (P＞0.05). PWV highly correlates with the artery blood pressure.

实验测定的结果表明，弦脉的脉搏波速度比同龄组平脉有显著性增大(P＜0.01或P＜0.05)，细脉的脉搏波速度比同龄组平脉有所减小(P＜0.05)，而滑脉与同龄组的平脉相比无显著性差异(P＞0.05)；脉搏波速度与动脉血压之间具有很大的相关性。

Result: Contrary to European and American people, I allele frequency of Han nationality is higher than that of D allele (P.05); II genotype frequency and DD genotype frequency are noticeably different from that of European and American people (P.01); No DD genotype appear in the excellent athletes, which is noticeably lower than that of control group and athlete group (P.05) and that of the excellent athletes reported in other countries; the frequency distribution of II genotype in Marathon is noticeably higher than that in 5km distance running(P.10); The changing of I allele Jl genotype IP ID genotype frequency indicates a stronger unary liner relation (r=0.9985) with the running distance lengthening(5ktru lOkrru Marathon).

结果显示：与欧美人群相反，汉族I等位基因频率高于D等位基因（P＜0.05）；汉族II型纯合子频率和DD型纯合子频率非常显著地区别于欧美人群（P＜0.01）；在优秀运动员中，DD型纯合子未出现一例，显著低于对照组和运动员（P＜0.05），也显著低于国外已报道的优秀运动员；马拉松项目II型频率分布显著高于5km（P＜0.10）；I等位基因、II基因型和ID基因型的频率变化伴随专项距离（5km、10km、马拉松）的增加呈现强相关的一元线性关系（r=0.9985）。

The comparison was made of amplitudes of the postsynaptic potential evoked in AP cells by the stimulation of T, P and N cells. The results showed that for each type of T, P and N cell the contralateral member of the pair evoked larger synaptic potentials in the AP cell that did its ipsilateral homologue and the T, P and N cell with a dorsally situated receptive field produced a larger synaptic input on the AP cell that its counterpart with a ventrally situated receptive field.

分别比较T、P和N细胞在AP细胞上引起的突触后电位的幅度，可见对侧T、P和N细胞在AP细胞上引起的突触后电位幅度比同侧的T、P和N细胞在AP细胞上引起的突触后电位幅度大；具有背部感受野的T、P和N细胞在AP细胞上引起的突触后电位的幅度比具有腹部感受野的T、P和N细胞在AP细胞上引起的突触后电位的幅度大。

P 0.05. Total ruminal bacteria, proteolytic and amylolytic bacteria, and protozoa in rumen enumerated by culture method all increased (P 0.05) in the Trial period. Real-time PCR analysis was used to compare Pre-trial and Trial populations of cellulolytic species, including Butyrivibrio fibrisolvens, Ruminococcus flavefaciens and Ruminococcus albus, which were increased by 7.0, 4.5 and 9.6%(P 0.05), respectively. Two starch-fermenting bacteria species, Streptococcus bovis and Ruminobacter amylophilus, were increased by 25.4% and 14.6%(P 0.05), respectively.

3.02，P 0.05。传统培养法结果表明，与对照期相比，BSN2处理期奶牛瘤胃中瘤胃细菌、蛋白分解菌、淀粉分解菌和原虫数量显著增加；实时定量PCR结果表明，试验期奶牛瘤胃纤维分解菌，包括溶纤维丁酸弧菌、黄色瘤胃球菌和白色瘤胃球菌数量分别提高6.97%、4.51%和9.6%(P 0.05)，两种淀粉分解菌，牛链球菌和嗜淀粉瘤胃杆菌分别提高25.4%和14.6%(P 0.05)，乳酸利用菌埃氏巨球型菌也提高8.85%(P 0.05)。

For fixed generalized reflection matrix P, i.e., P^T=P, P^2=I, then matrix X is said to be generalized bisymmetric, if $X=PXP$ and $X=X^T$.

对于某个广义反射阵P，满足P^T=P， P^2=I，那么称矩阵X是广义双对称的，如果满足X=PXP及X=X^T。

Results: HE stain showed the obvious thicken of the artery, RV/ and mPAP elevated obviously (P.05) in model group in comparison with the control group, they were also elevated obviously (P.05) in the model group compared with the treatment group. The tryptase + mast cell and the chymase + mast cell obviously increased in the model group compared with the control group, also increased in the model group compared with the treatment group.

平均肺动脉压力模型组动物较对照组明显升高(P.05)，模型组较治疗组也明显升高(P.05)；右心室／模型组较对照组明显增加(P.05)，模型组较治疗组也明显增加(P.05)，肥大细胞总数（类胰蛋白酶阳性的肥大细胞）及类糜蛋白酶阳性的肥大细胞模型组较对照组明显增多(P.05)，肥大细胞在治疗组较模型组明显减少(P.05)。

Result: At most up to 500 mg·L-1, tetrahydropalmatine showed no sinificant effect on the cell viability, while dehydrocorydaline, berberine and palmatine significantly decreased the cell viability, exceeding 6.3, 0.6 and 6.3 mg·L-1, respectively（ P .05 or P .01）. Tetrahydropalmatine, dehydrocorydaline, berberine and palmatine significantly inhibited LDH leakage induced by anoxia-reoxia injury, at concentrations of 50-100, 1.25-5, 4 and 30 mg·L-1, respectively（ P .05 or P .01）. None of the four compounds showed significant effect on the hydrogen peroxide injury.

结果：多至500 mg·L-1的延胡索乙素对细胞活力无任何影响，脱氢紫堇碱、黄连素、巴马汀分别在质量浓度大于6.3， 0.6，6.3 mg·L-1时，显著降低细胞活力（ P 。05， P 。01）；延胡索乙素、脱氢紫堇碱、黄连素和巴马汀分别在质量浓度为50～100， 1.25～5， 4，30 mg·L-1时，显著抑制缺氧复氧导致的LDH漏出（ P 。05， P 。01）；4种单体对过氧化氢损伤无显著的保护作用。

Results: Tyroserleutide can significantly increase the life span of H22 tumor-bearing mice by 50-70% in dosages of 20ug/kg/d-80ug/kg/d,specially the high dosage of 80ug/ml can significantly increase the life span by 69.24%; Tyroserleutide can inhibit the growth of transplanted hepatocellular tumor BEL-7402 in nude mice,the rate of tumor inhibition was25-50% in dosages of 40-320ug/ml ,the inhibition rate of 160ng/ml was 44.03%; Tyroserleutide could inhibit the growth of H22 and BEL-7402 tumor in a dose-dependent manner. Simultaneously, tumoricidal activity of tyroserleutide against BEL-7402 cell line in vitro was observed hinger when compared with the control group(P.05).The inhibition effect of 72hrs was higher than 24hrs,48hrs,96hrs.And specially the high dosage of 160ug/ml can significantly inhibit growth of tumor cell by 19.36%. Tyroserleutide can activated PEM and marked enhance cytotoxicity andphagocytosis functions in vitro and in vivo. The OD values of cytotoxicity were observed hinger when compared with the control group(P.05).The cytotoxicity of macrophages activated by tyroserleutide against BEL-7402 and B16-F10 was 35.58%,61.2% in vitro and21.39%,47.63% in vivo. The cytotoxicity rate of nude mice PEM was 32.86%,73.07% in vivo. Furthermore, tyroserleutide alone could stimulated the production of IL-1B TNF- a and NO by M . Tyroserleutide and LPS could synergistically activated M producing more cytotoxicity effectors. Conclusion: Tyroserleutide had inhibition functions against hepatoma carcinoma .Its possible mechanisms were related to the affect that Tyroserleutide could inhibit tumor cell directively and induce tumor cells apoptosis or death effectively.

结果：酪丝亮肽能显著延长腹水型肝癌H_(22)小鼠的生存时间，给药剂量为80μg／kg／d时疗效最显著，达到69.24％，在20μg／kg／d-80μg／kg／d剂量范围内生命延长率为50-70％，给药剂量与荷瘤鼠生存时间呈现一定量效关系；酪丝亮肽能显著抑制人肝癌BEL-7402移植瘤裸鼠的肿瘤生长，给药剂量为160μg／kg／d时疗效最显著，抑制率为44.03％，并且在40-320μg／kg／d剂量范围内抑制率为25-50％，给药剂量与肿瘤抑制率呈现一定量效关系；酪丝亮肽体外对人肝癌BEL-7402细胞生长有一定的抑制作用，在作用72hrs时各浓度酪丝亮肽对肿瘤细胞的抑制作用较24hrs、48hrs、96hrs明显，其中浓度为100μg／ml时抑制率达19.36％；酪丝亮肽体内外均能增强小鼠腹腔巨噬细胞对肿瘤细胞的杀伤：体外作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与效应细胞对照组相比有显著性差异(P＜0.05)杀伤率分别达到35.58％、61.2％；体内作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P 。05)，杀伤率分别达到21.39%、47.63%；裸鼠腹腔巨噬细胞经酪丝亮肤作用后对BEL一7402、B 16一F10杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P.05)，最高杀伤率分别达到32.86%、73.07%；酪丝亮肤能增强单核巨噬细胞系统的吞噬功能，吞噬指数与生理盐水组比较有显著性差异(P.05)；酪丝亮肤体外作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与效应细胞对照组相比有显著性差异(P.05)；酪丝亮肤体内作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与生理盐水对照组相比有显著性差异(P.05)；酪丝亮肤能促进鼠巨噬细胞株R戌W264.7分泌合成IL一1p和NO，IL一1日、NO水平分别在酪丝亮肤作用24hrs、12hrs时达到高峰，酪丝亮肤单独应用能提高巨噬细胞的分泌合成功能，而且酪丝亮肤能与LPS协同作用刺激巨噬细胞的细胞毒效应分子分泌合成。

In hypoxia/reoxygenation model(Na2S2O4), cell survival was enhanced and LDH in culture medium was reduced(P.05, P.01) after treated with 60, 30μgmL^(-1) Sanguis Draconis flavones. Enhanced cell survival and reduced LDH in culture medium(P.05, P.01) also observed in cytotoxicity model induced by H2O2 after incubated with 60, 30, 15μgmL^(-1) Sanguis Draconis flavones.

在缺氧／复氧(Na2S2O4)模型中，60、30μgmL^(-1)龙血竭总黄酮能显著降低培养液中的LDH浓度，增强细胞活力(P.05， P.01)。60、30、15μgmL^(-1)龙血竭总黄酮能抑制H2O2引起的损伤，降低培养液中LDH的浓度，增强受损细胞活力(P.05， P.01)。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失