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Results:The rate of tumor shrinkage and necrosis was 46.8% and 20.7%,while the contrast group was 78.9%,49.2% respectively(P<0.05).There were significant difference(P<0.05)for 2year survival rate in singlelesion group,nondistant metastasis group and combinedtherapy group.

结果:单纯TACE组的肿瘤总缩小率和肿瘤完全坏死率分别为46.8%和20.7%,联合治疗组分别为78.9%、49.2%(P均<0.05),单病灶组、无转移灶组及联合治疗组的2年生存率高于多病灶组、有转移组和单纯TACE组(P均<0.05)。

Results: After treatment, the histopathology and intestinal metaplasia subset of antral focal region, and the background lesion in ultrastructure of the mucosa in the nonfocal region were all improved in the 4 groups, The effects of Spleen-Qi Deficiency syndrome group and Spleen-Yang Deficiency group were superior to Ying-Deficiency group as well as Spleen-Deficiency and Qi-Stagnation group (P<0.05, P<0.01), and approached to those in the healthy control group.

结果:脾气虚证与脾阳虚证病理疗效优于脾阴虚证和脾虚气滞证(P<0.05,P<0.01);4组脾虚证胃窦部病灶区组织病理、肠化生亚型和非病灶区粘膜超微结构中的&背景病变&,在治疗后均有改善,趋向接近于健康对照组。

All results above indicated that:The expression of ERβand p-ERβin mouse ovary at oestrous cycle and in early gestational period changed regularly, it showed that ERβand p-ERβhad important effects to ovaries development, ovarian follicles groth, oocyte maturation and form corepus luteum in female mouse ovary during oestrous cycle and in early gestational period.

以上结果表明:ERβ及其磷酸化形式——p-ERβ在小鼠发情周期以及妊娠早期卵巢中表达有规律性的变化,揭示ERβ与p-ERβ在雌性小鼠发情周期及妊娠早期,对卵巢发育、卵泡生长、卵母细胞成熟和黄体形成有重要的作用。

Results Serum was much lower (P<0.05) during hypotension shock stage and diuretic stage, and significantly lower(P<0.01) during oliguria stage.

结果 HFRS患者在低血压休克期和多尿期时血清含量降低(P<0.05),以少尿期最为显著(P<0.01)。

Results: OVX group, with weakened bone structure, had decreased cancellous bone and increased parameters of osteal formation and resorption compared with Sham, OVX+E and OVX+E+P groups(P.05). The bone mass, osteal formation and resorption in group OVX+P had no significant changes.

结果:与假手术组、雌激素及雌孕激素组相比,去卵巢大鼠松质骨骨量明显减少,伴有骨结构变差,骨形成和骨吸收的参数值增加(P.05);与去卵巢组相比,孕激素组大鼠无显著改变。

Alkyl manganese pentacarbonyl compounds5MnR (R = CH3, p-CH2C6H4CH3, p-CH2C6H4OCH3) were synthesized by metalation of manganese pentacarbony potassium salt with corresponding alkyl halides in ether. Photolysis of these with 1-2 equivalent of (CH3)2(C6H5)SiH or (CH3)(C6H5)2SiH in C6D6 solution at 5℃ produces silyl manganese pentacarbonyl compounds5MnSi(C6H5)(CH3)2 and5MnSi(C6H5)2(CH3) respectively (yield 70-88%).

用五羰基锰钾盐和相应的卤代物在乙醚中的金属化反应合成了五羰基锰烷基合物5MnR(R = CH3,p-CH2C6H4CH3, p-CH2C6H4OCH3 ),产率达到72-93%,将这些化合物与1-2当量(CH3)2(C6H5)SiH和(CH3)(C6H5)2SiH的C6D6溶液在5℃光解,分别得到五羰基锰硅烷基化合物5MnSi(C6H5)(CH3)2和5MnSi(C6H5)2(CH3)(产率达到70-88%)。

The structure of the compound 〓(1) consists of a pentanuclear molecule which is center-symmetric. One W atom is coordinated by four S atoms and two Cu atom. As expected, the Fe atoms are sandwiched between two staggered pentadiene rings. The most interesting aspect of the structure is that Fe-C-P-Cu-P-Cconstitutes a distorted hexagon and Fe-Cu-W-Cu-Fe is nearly in a line.

结构是以W原子为对称中心含有五个金属原子的线型结构,W原子与四个μ〓-S和两个Cu原子配位;Fe原子在两个戊二烯环中间形成一个三明治夹心结构;Fe〓-C〓-P〓-Cu〓-P〓-C〓-构成扭曲的六边形,由于两边1,1'-双二茂铁配体的作用导致Cu-S键的拉长。

The results were as follows: Compared with control group, the weight and the relative weight of thymuses, bursas of Fabricius and spleens of experiment group increased significantly(P<0.05) or extremely significantly(P<0.01). In experiment group, the cortex of thymic lobule, bursa nodule and Periarterial Lymphatic Sheaths thicken obviously; the volume of bursa nodule, splenic nodule and ellipsoid augmented, and the germinal center of splenic nodule were obvious; the thymic corpuscle increased; the plica of bursas of Fabricius developed well and the degenerating of it retarded.

结果表明:试验组鸡胸腺、腔上囊、脾的重量和器官指数均高于对照组,差异显著(P<0.05)或极显著(P<0.01);试验组的胸腺小叶皮质增厚,胸腺小体增多;腔上囊皱襞发达,腔上囊小结体积大,皮质较厚,退化延缓;脾的动脉周围淋巴鞘增厚,脾小结体积大,生发中心明显,椭球增大。

Multivariate regression analysis determined that both tumor necrosis(P=0.01) and perineurial invasion(P=0.01) independently related to long-term survival.

多元回归分析证实肿瘤坏死(P=0.01)和神经囊膜侵润(P=0.03)分别与长期生存有关。

The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P<0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P<0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝脏ERα及其mRNA基因的表达分布于肝细胞及肝脏非实质细胞,特别以肝脏中央静脉和门脉周围为主;卵巢切除减少ERα及其mRNA基因的表达(P<0.05);雌二醇治疗在肝纤维化和卵巢切除大鼠均提高肝脏ER及其mRNA基因的表达(P<0.05),其增加程度与肝脏组织学损伤、纤维化指标的降低程度以及肝脏胶原沉积减少相平行。

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