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On the presentation of Mn-P fixation, this paper reviews the latest advances in recent 10 years and concentrates on the mechanism of phosphorus fixation in acid soils. In addition, it brakes through the classical inorganic P fractionation in to Fe-P, Al-P, O-P and Ca-Pin the traditional P classification and considers Mn-P as one of the main phosphorus fixation modes in latosols, cultivated from the parent basalt material. Furthermore, fixation of P by Fe, Al, Mn is compared, and differentiation from chemical availability and bioavailability of P discussed. Based on the above, this paper presents some alienable measures for enhancing P utilization efficiency and postulates pivotal future research directions in the field of P fixation.

本文以Mn-P的提出为出发点,论述了近10年来对酸性土壤固磷机理研究的新进展,突破了常规P素形态分级研究中分为Fe-P,Al-P,O-P和Ca-P等无机磷测定的经典分级,认为玄武岩母质砖红壤中的Mn-P是P素固定的主要形式之一,进而比较了Fe、Al、Mn对P固定作用,并从P的化学有效性与生物有效性差异等方面进行了比较全面的论述,提出了减少P素固定提高磷肥利用率的措施及今后的重点研究方向。

Paired Samples T test revealed that both the LT and VL decreased (P.01), the AD increased (P.01) after cycloplegia regardless of their refractive state. The AL increased for hyperopic eyes (P.05) and decreased for myopic eyes (P.01) after cycloplegia. For hyperopic eyes, the major keratometer K1 increased (P.05) while for myopic eyes, the major keratometer K1(P.05) and minor keratometer K2 (P.01) decreased after cycloplegia. The mean corneal power of zones 5 mm (MD5) and 7 mm (MD7) decreased with myopic eyes decreased dramatically (P.01). The mean refractive power of the lower half vertical meridian is greater than that of upper half; and the mean refractive power of the lateral half of the horizontal is greater than that of the medial half.

结果:不论远视眼、正视眼还是近视眼在睫状肌麻痹后前房加深(P.01),晶状体变薄(P.01),玻璃体腔径缩短(P.01);但远视眼睫状肌麻痹后眼轴增长(P.05),近视眼眼轴缩短(P.01);远视眼睫状肌麻痹后角膜曲率K1增加(P.05),近视眼睫状肌麻痹后除K1降低外(P.05),K2以及以角膜中心点为中心,直径为5mm、7mm的环平均角膜屈光度(MD5、MD7)均降低(P.01);此外,垂直径线上方的平均角膜屈光度小于下方的平均角膜屈光度而水平径线鼻侧的平均角膜屈光度小于颞侧的平均角膜屈光度(P.01)。

The incidence of anxiety and depression in patients with FD was higher than that in healthy volunteers; The average extent of anxiety and depression of FD patients was significantly higher than that of healthy people (p 0.001). 2.The total scores of life events and the scores of negative life events in patients with FD was significantly higher than that of healthy group (p=0.014 and p 0.001), but the favorable life events scores was lower than healthy group's(p=0.001). 3. Eight healthy conceptions in the health-related quality of life of FD patients was significantly lower than that of healthy volunteers (p .001). 4. There was positive correlation among the symptom iterated integral, anxiety evaluation and depression evaluation of the FD patients (p0.001). 5. In the FD patients, there was no significant correlation between the evaluation of symptoms and life events. 6. In the FD patients, there was no significant correlation among symptoms evaluation, energy and body ache, and negative correlation among the other 6 health conceptions (p 0.05). 7. There was significant positive correlation among the total scores of life events、negative life events scores and anxiety evaluation of the FD patients(p.01),and also with depression evaluation(p.05),there was no significant correlation among the favorable life events scores with anxiety and depression evaluation both. 8. There was negative correlation among anxiety evaluation, depression evaluation and 8 health conceptions of the FD patients (p 0.001). 9. There existed negative correlation respectively among the total scores of life events and negative life events scores with 6 health conceptions of the FD patients (p 0.05) and 7 health conceptions of the FD patients (p 0.05), there was no significant correlation among the favorable life events scores and the health-related quality of life of FD patients.

结果:1、FD患者焦虑、抑郁的发生率明显高于健康对照组(p.005),平均焦虑、抑郁程度高于对照组(p.001)。2、FD患者经历的生活事件总值(p=0.014)和负性生活事件值(p.001)明显高于健康对照组,正性生活事件值低于对照组(p=0.001)。3、FD患者的生活质量在8个健康概念上均明显比健康人差(p.001)。4、FD患者的症状积分与焦虑评分、抑郁评分呈正相关(p.001)。5、FD患者的症状积分与生活事件值均无相关性。6、FD患者症状积分与活力、躯体疼痛之间无明显相关性,与其余6项健康概念均呈负相关(p.05)。7、FD患者的生活事件总值、负性生活事件值与焦虑评分均显著正相关(p.01),与抑郁评分也均呈正相关(p.05),正性生活事件值与焦虑和抑郁水平均无相关性。8、FD患者焦虑评分、抑郁评分与8项健康概念均呈负相关(p.001)。9、FD患者生活事件总值和负性生活事件值分别与生活质量8项健康概念中的6项和7项呈负相关(p.05),正性生活事件值与生活质量无关。

Dibutyltin maleate,dioctyltin maleate,N-phenyl maleimide, N-(p-chlorophenyl) maleimide,N-(p-nitrophenyl) maleimide with unsaturated groups were synthesized using dibutyltin oxide,dioctyltin oxide,maleic anhydride, aniline,p-chloroaniline,p-nitroaniline as raw materials,respectively.Then dibutyltin male,ate/styrene bipolymer,dibutyltin maleate/styrene/methyl acrylate terpolymer,dibutyltin maleate/styrene/N-phenyl maleimide terpolymer ,dibutyltin maleate/styrene/N-(p-chlorophenyl) maleimide terpolymer ,dibutyltin maleate/styrene/N-(p-nitrophenyl) maleimide terpolymer ,dioctyltin maleate/styrene biopolymer,dioctyltin maleate/styrene/methyl acrylate terpolymer,dioctyltin maleate/styrene/ N-phenyl maleimide terpolymer,dioctyltin maleate/styrene/ N-(p-ehlorophenyl) maleimide terpolymer[P(DOTM/St/NC1PMI)],dioctyltin maleate/styrene/N-(p-nitrophenyl) maleimide terpolymerwere synthesized using DBTO,DOTO,PMI,N-p-ClPMI,N-p-NOPMI,styrene and methyl acrylate as monomers,respectively.

再以DBTO,DOTO,PMI,N-p-ClPMI,N-p-NOPMI,苯乙烯,丙烯酸甲酯等为单体,合成了马来酸二丁基锡/苯乙烯二元共聚物{P},马来酸二丁基锡/苯乙烯/丙烯酸甲酯三元共聚物{P},马来酸二丁基锡/苯乙烯/N-苯基马来酰亚胺三元共聚物{P(DBTM/St/NPMI)},马来酸二丁基锡/苯乙烯/N-对氯苯基马来酰亚胺三元共聚物{P(DBTM/St/NClPMI)},马来酸二丁基锡/苯乙烯/N-对硝基苯基马来酰亚胺三元共聚物{P(DBTM/St/NNOPMI)},马来酸二辛基锡/苯乙烯二元共聚物{P},马来酸二辛基锡/苯乙烯/丙烯酸甲酯三元共聚物{P},马来酸二辛基锡/苯乙烯/N-苯基马来酰亚胺三元共聚物{P(DOTM/St/NPMI)},马来酸二辛基锡/苯乙烯/N-对氯苯基马来酰亚胺三元共聚物{P(DOTM/St/NClPMI)},马来酸二辛基锡/苯乙烯/N-对硝基苯基马来酰亚胺三元共聚物{P(DOTM/St/NNOPMI)}。

The results showed that there were inadaptive responses,and there were significant differences (P<0.01) among all levels. There were less inadaptive responses in the secondary nursing students than in the baccalaureate standard(P<0.05) and college nursing students (P<0.05); The Basic Physiologic Needs and the Role Mastery were not significantly difference among different level nursing students (P>0.05); The difference in the self-Concept and in the interdependence was significant (P<0.01). There were less inadaptive responses in the secondary nursing students than the BSN(P<0.05) and college nursing students (P<0.05) in the Self-concept; there were more inadaptive responses in the BSN than that in the college (P<0.05) and secondary(P<0.01) nursing students,and the difference was not significant among the college nursing students and secondary nursing students in the Interdependence.

结果表明:不同层次护生在毕业实习期均存在不适应反应,不同学历间有显著差异(P<0.01),中专护生不适应反应少于本科(P<0.05)及大专护生(P<0.05),在生理需要及角色功能方面,不同学历间无显著性差异(P>0.05),在自我概念方面,不同学历间存在显著性差异(P<0.01),中专护生少于本科(P<0.01)及大专(P<0.05)护生,在互相依赖方面,不同学历间存在显著性差异(P<0.01),本科护生多于大专(P<0.05)及中专(P<0.01)护生,大专与中专护生间无显著性差异(P>0.05)。

Results: Compared with IR group , XSOL could significantly decrease the cerebral water content, the cerebral index, the brain vascular permeability in rats of acute incomplete brain ischemia-reperfusion (P.01,P.05). Cerebral tissue morphology showed that neuronic damage of rats subjected to acute incomplete brain ischemia-reperfusion was ameliorated following administration of XSOL (2.4, 9.6g/kg). Compared with IR group , XSOL could significantly decrease the content of MDA and NO in brain tissue(P.01,P.05)and increase SOD,GSH-px activity. The levels of cerebral Glu,Asp were cut down(P.01,P.05). Conclusion: XSOL shows protective effects on cerebral ischemia-reperfusion.

结果:与缺血再灌注组比较,XSOL大、小剂量组可以显著降低急性不完全性脑缺血再灌注模型大鼠的脑含水量(P.01,P.05)、脑指数(P.01,P.05)、脑毛细血管通透性(P.01,P.05);光镜下脑组织形态学显示各剂量组可不同程度的减轻急性不完全性脑缺血再灌注大鼠脑组织的神经元受损形态;与缺血再灌注组比较,XSOL大、小剂量组可以显著降低缺血再灌注大鼠脑组织中的MDA的含量(P.01,P.05),升高SOD、GSH-Px在脑组织中的活性(P.01,P.05);XSOL大、小剂量组可显著降低脑组织中NO的含量(P.01,P.05),降低脑组织中Glu、Asp含量(P.01,P.05)。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P<0.05, P<0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P<0.05, P<0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P<0.05, P<0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P<0.05,P<0.01),thus restrain the occurrence of synovial tissue inflammation.

结果:(1)电针疏密波组能显著减轻踝关节肿胀度(P<0.05,P<0.01),表明电针有明显的抗炎消肿作用;(2)HE染色显示:电针疏密波组可使大鼠关节炎症细胞浸润明显减轻,滑膜细胞增生明显被抑制,肉芽组织增生明显减少;(3)电针密波组能提高实验性大鼠痛阈(P<0.05,P<0.01),降低外周疼痛介质K~+、DA、5-HT的含量(P<0.05,P<0.01),表明电针有明显的镇痛作用;(4)在病变关节局部,电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P<0.05,P<0.01),升高IL-4的含量(P<0.05,P<0.01),并降低关节滑膜内COX-2mRNA的表达(P<0.05,P<0.01),可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P<0.05,P<0.01),从而抑止滑膜组织炎症发生。

These 375 patients had a median age of 50.57±10.46(range,19-72) with 87.4%HBsAg positive and 4.3%anti-HCV antibody positive;The apparent peak incidence age was 40~60 years old,and the ratio of male to female was 10.7:1;The 3 and 5 year postoperational survival rate were 52%and 38%;The tumour numbers(p=0.000),tumor size(p=0.025),histological pattern (p=0.000),nuclear features(p=0.000),differentiation(p=0.001) and vascular invasion(p=0.000) were significantly correlated with prognosis.The postoperational survival time of thin trabeculae pattern,compact pattern and pseudoglandular pattern were significantly longer than that of thick trabeculae, scirrhous pattern,and solid patternp<0.009the postoperational survival time of 1 and 2 grade based on nuclear features were significantly longer than that of 3 and 4 grades(p=0.000The small cell variant,osteoclast-like giant cell variant, and spindle cell variant were mainly composed of thick trabeculae pattern and solid pattern,which were significantly different from that of clear cell variant.

结果1。本组资料显示肝细胞癌发病年龄19~72岁,平均50.57±10.46岁,发病高峰年龄40~60岁,男女比例为10.7:1;HBsAg87.4%,anti-HCV抗体4.3%;术后3年生存率为52%,5年生存率为38%;肿瘤数目(p=0.000)、肿瘤大小(p=0.025)、组织学结构类型(p=0.000)、核分级(p=0.000)、分化程度(p=0.001)及血管浸润均(p=0.000)与预后明显相关;其中组织学结构类型中细梁状型生存时间与致密梁状型和腺样型无明显区别(p>0.05)而明显高于粗梁状型、实性型和硬化型(p≤0.009),硬化型生存时间与实性型之间无明显区(p>0.05)而明显低于其余各型p≤0.006核分级1级与2级生存时间无明显区别(p>0.05,核分级3级与4级生存时间无明显区别(p>0.05),而核分级3级生存时间明显低于2p=0.000小细胞型、巨细胞型和梭形细胞型主要由实性型和粗梁状型组织学结构类型构成,明显不同于透明细胞型(主要由细梁状型和粗梁状型构成(p≤1.006)。2。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

The uptake rate and equilibrium time of organochlorine pesticides were obtained during the laboratory experiment. All the equilibrium time are 594 hours except that δ-BHC's is 234 hours and both p, p'-DDE and o, p-DDT's are 70 hours. Uptake rates of α-BHC, hexachlorobenzene,β-BHC,γ-BHC,δ-BHC, heptachlor, aldrin, heptachlor epoxide, p, p'-DDE, dieldrin, endrin, p, p'-DDD, o, p-DDT and p, p'-DDT are 0.061, 0.071, 0.098, 0.066, 0.033, 0.014, 0.007, 0.062, 0.108, 0.052, 0.029, 0.032, 0.061mL/h, respectively.

得出了有机氯农药在水相和半透膜之间分配的平衡时间和富集系数,平衡时间除δ-BHC为234h和p,p'-DDE、o,p-DDT为70h外,其余组分均为594h;α-BHC、六氯苯、β-BHC、γ-BHC、δ-BHC、七氯、艾氏剂、七氯环氧、p,p'-DDE、狄氏剂、异狄氏剂、p,p'-DDD、o,p'-DDT、p,p'-DDT富集系数分别为:0.061、0.071、0.098、0.066、0.033、0.014、0.007、0.062、0.108、0.052、0.029、0.032、0.061mL/h。

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P.R.E.N.U.P.
F.C.P.S.I.T.S.G.E.P.G.E.P.G.E.P.
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