查询词典 osteoclast

In vivo, CD11b+-cre/Dicer-null mice had mild osteopetrosis due to decreased osteoclast number and bone resorption.

体内实验发现，由于破骨细胞数目减少以及骨吸收作用降低，CD11b+-cre/Dicer-null小鼠表现出轻微的骨硬化症。

The osteoclast is a member of the monocyte/macrophage family, decreased or increased number and activity of osteoclasts respectively causes osteopetrosis or osteoporosis and other osteolytic diseases.

破骨细胞来源于单核／巨噬细胞谱系，其数量和活性的不足或增加分别会导致骨硬化症和骨质疏松及其他溶骨性疾病。

Autosomal recessive osteopetrosis is characterized by insufficient osteoclast activity resulting in defective bone resorption and marked increase in skeletal mass and density.

人体胫骨不同骨密度条件下不同骨病理的骨细胞形态─存在机械感受作用吗？

Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in osteoclast differentiation.

因此，钙敏感受体基因和白介素6基因都为骨矿物质代谢的重要候选基因。

Many investigations make clear that Osteoelast, prosoma of Osteoclast, Osteoblast all can express NOS. NOS activation receive the induction of Ca2+, Calmodulin, cytokine and endotoxin.

许多研究表明破骨细胞及破骨细胞前体、成骨细胞均能表达一氧化氮合成酶，NOS的激活受Ca~(2+)和钙调蛋白或细胞因子和内毒素诱导。

Bone is a complex tissue composed of several cell types and the two major of them responsible for bone remodelling are osteoclast, which resorb bone, and osteoblast, which form new bone.

中文摘要骨骼是具有数种细胞型态的复杂组织，而其中最重要的两种分别是负责骨吸收作用的破骨细胞及职司骨生成的造骨细胞。

ESEM showed on one highly mineralized construct that partial displacement of oneosteoclast exposed specialized structures of the cellular membrane facing the bonesurface, namely, the ruffled border and podosomes of the sealing zone, as well as theresorption pit under the ruffled border, unequivocally indicating that osteoclast-likecells formed have the ability to resorb bone-like matrix produced by osteoblasts invitro.

细胞在大矿化结节周围分布的差异反映了在大小类似的情况下，结节矿化程度越高，对周围的TRAP阳性细胞的趋化能力越强。F-actin荧光染色显示了在大矿化节结上F-actin环的出现，这是破骨细胞具有吸收活性的特征标志，直接证明了所形成的类破骨细胞具有骨吸收活性。

In this study, we investigated the expression of osteoblast differentiation and osteoclast differenation by adlay extract, benzopyrene and tributyltin, three environmental estogens.

在本实验中，我们观察三种环境雌激素样物质：薏苡仁水萃取物、苯骈芘及三丁基锡对造骨细胞和破骨细胞分化的影响。

According to our results, since BaP increased the expression of COX2 and pp38 to reduce the osteoblast differentiation and this phenomenon can reverse by treatment of NS398, but not by treatment of SB203580, suggesting that COX2 activation plays an important role on osteoblast differentiation. Adlay could increase osteoblast differentiation, in co-culture system, and reverse the osteoporotic status in mice, would be a helpful healthy food for enhance osteoblast differentiation. However, about, TBT, we didn't have enough data to support its effect on the differentiation of osteoblast or osteoclast.

所以依据我们所做出的实验结果，虽然苯骈芘会增加COX2和pp38的蛋白表现，但造骨细胞的分化作用仍下降，但若同时添加NS398，则分化能力有恢复现象，这或许可推测说COX2活性在抑制造骨细胞分化上扮演了一个重要角色；薏苡仁在共同细胞培养可以增加造骨细胞的分化作用，且对骨质疏松状态的小鼠具有缓解的能力，因此或许是能促进造骨细胞分化的营养食品；至於三丁基锡由於实验的数据不多，推测其或许并不影响造骨细胞和破骨细胞的分化作用。

Results MMP-2 immunohistochemical results indicated that the MMP-2 expression increased and was observed on both sides periodontium of movement tooth, osteoclast, cementoblast, osteocyte, fibroblast and osteoblast appeared positive.

结果MMP-2免疫组化结果显示牙齿移动后，牙周膜两侧MMP-2表达增加，破骨细胞、骨细胞、成纤维细胞和部分成骨细胞MMP-2染色阳性。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。