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The cytotoxicity of these compounds were valuated by MTT and SRB methods using three cancer cell lines: HL-60, A-549, P-388. Cyclo-shikonin, and cyclo-alkannin have high cytotoxicity against HL-60.The chiral center of side chain has no effect on their activity. 2- 1-(Acetyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (105) has strong inhibition effect on P-388 cells. 2- 1-(isooctyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (108) and 2- 1-(2-furoyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (112) have high inhibition on A-549.Shikonin (1), alkannin (2), and their derivatives have the structural features of a planar chromophores and short side chain. We examined the ability to inhibit the telomerase.

抗肿瘤活性初步筛选测试采用小鼠白血病P-388肿瘤细胞和人肺癌A-549肿瘤细胞进行，结果表明侧链羟基的手性对抗肿瘤活性无明显影响；有数个化合物具有很好的体外抑制活性，特别是化合物2-（1-异辛酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（108）和2-[1-（2-呋喃甲酰氧基）-4-甲基-3-戊烯基]-5，8-二羟基-1，4-萘醌（112）体外显示对人肺癌A-549肿瘤细胞有强效；2-（1-乙酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（105）对小鼠白血病P-388肿瘤细胞有强效；环紫草素和环异紫草素对人白血病HL-60细胞有强烈抑制作用。

The trials on cultivation of Atriplex canescensconducted in Minqin Desert Control Experiment Station reveals that this speciesentails fine qualities as strong tolerance in drought, cold, salinity and low temperatureas well as high annual biomass. So it cab be extended in sandy areas with favorableirrigation condition, and on hilly in loess plateau with relatively high rainfall and lowevaporation. As a new substitute species for water/soil conservation and rangelandregeneration, it has a big potential to be extended. However, more research on withinwhich scope this species can be extended need to be done

从干旱沙区民勤治沙综合试验站的栽培来看，四翅滨藜在此地表现出了耐旱、耐寒、耐盐碱、耐低温且年生长量大的优良特性，因此可以在有灌溉条件的沙区和降雨较多且蒸发较小的黄土丘陵区进行推广，作为该地区的水土保持和草场更新的新物种，具有一定的推广潜力，但推广地域范围的划分，仍需进一步的试验研究和充分的科学论证。

Results MRI of all WE patients showed symmetrical high signals on the brain T2WI, Flair and diffusion weighted imaging, 6 cases of them in the medial thalamus, 4 cases in surrounding the aqueduct, 3 cases in the third ventricle gray matter, 2 cases in the mamillary bodies, 1 case in the putamen,1 case in the optic chiasm, 1 case in the superior cerebella vermis and 1 case in the subcortical white matter; 2 cases had reinforcement effect. 2 cases showed no abnormal signals on T2WI and Flair early, but showed high signal symmetrically in the medial thalamus on DWI imaging.

结果 8例WE患者MRI示脑部T2WI、Flair成像及弥散加权成像有对称性异常高信号影，其中出现在丘脑内侧6例、中脑导水管周围灰质4例、第三脑室周围灰质3例、乳头体2例及壳核、视交叉、小脑上蚓部、皮质下白质各1例；2例有增强效应。2例发病早期T2WI、Flair无异常信号影，DWI示丘脑内侧对称性异常高信号影。

Therein, by adopting the ISCSI protocol, the local data storage sub-system constructs the circuital access pattern of the taxation data. The system eliminates the unbalance phenomena between the capability and the demand of the data storage under the traditional bus storage pattern. Under the centralized control pattern, it provides the information access and shares service with the great data volume, the high speed of data transportation and the high availability for the taxation system. By remotely building a backup data center that is totally consistent with the local data center on the IT foundational fabric, the remote data backup sub-system uses the geographical dispersibility of the remote data center and adopts the LVR software replication technology. It implements the synchronous data replication between the local and remote data center, changes the zero standing capability on the great disaster event under the single data center pattern and raises the standing capability on the disaster events for the application and data in the taxation system. By adopting the dynamic replication technology between the heterogeneous data source, the heterogeneous data conformity sub-system successfully shields the various heterogeneous ingredients of the present system.

其中，本地数据存储子系统采用ISCSI协议构建了税务数据网络存储模式，消除了传统总线型存储模式下数据存储性能和存储需求之间的失衡现象，在集控管理模式下为税务系统提供了超大数据容量、高数据传输率和高可用性的信息存取和共享服务；远程数据备份子系统通过在异地构建一个和本地数据中心IT基础架构完全一致的备份数据中心，利用远程数据中心在地理上的分散性，基于LVR软件复制技术实现了本地和远程数据中心之间信息的实时同步，改变了过去单一数据中心模式下对大型灾难事件的零抗灾能力，提高了税务系统内应用和数据对灾难性事件的抵御能力；异构数据整合子系统采用异类数据源动态复制技术，成功屏蔽了目前系统内存在的各项异构成分。

In view of practical problem during Sulige gas field development, this paper complete follow study content. Study material balance theory of two district compound gas reservoir. Carry out stress sensitivity experiment on matrix rock and labor created fracture core from Sulige gas field with America Core Company high pressure high temperature flow experimental instrument to study stress sensitivity change rule of different permeability matrix rock and created fracture core at the condition of time and again switch on and off well and different drawdown pressure. Carry out depletion experiment on matrix rock of different permeability serial combination with different kinds of allocation, using double core clamper serial connected experimental apparatus, to study gas well production performance of bi-zonal compound low permeability reservoir during low pressure production stage. At the basis of experimental study, establish single well simulation model to analyze development index infection caused by stress sensibility and production performance infection rule caused by inner formation and outer formation of bi-zonal compound gas reservoir permeability variation while considering stress sensitivity.

针对苏里格低渗气田开发中存在的实际问题，完成以下研究内容；研究了两区复合气藏物质平衡原理；利用美国岩芯公司高温高压流动实验仪，对取自苏里格气田基质岩芯和人工造缝岩芯进行应力敏感实验，研究不同渗透率基质岩芯和造缝岩芯在多次开关井和不同生产压差条件下的应力敏感变化规律；采用双岩芯夹持器串联实验装置，对不同渗透率串联组合的基质岩芯进行各种配产条件下的衰竭实验，研究两区复合的低渗储层气井在低压生产阶段的生产动态特征；在实验研究的基础上，建立单井模拟模型分析储层应力敏感性和非均质性对开发指标的影响，研究考虑应力敏感时两区复合气藏储层中内区和外区渗透率变化对开发动态的影响规律。

By the furnace body, the stainless steel crucible, electrically operated toward the multiple swinging material frame, stainless steel fast Leng Bao, the heating unit and control the warm cabinet to be composed automatically, may use the different resolver, carries on components quenching, the tempering heating, the isothermal quench to cool, the liquid thermochemical treatment and so on many kinds of crafts, the furnace body becomes by the section and the steel plate welding, the stove surface uses δ=14mm the board to make, the nitre salt furnace lining uses the ultra light quality high strength 0.6g/cm3 micro bead refractory brick, clamps the stratification aluminum silicate textile fiber, the furnace lining and the furnace shell fills the heat preservation inflation heat preservation powder, the entire structure for the standard energy conservation furnace lining, the nitre salt stove's heating element uses the thick diameter 0Cr25Al5 high temperature resistance wire to circle spiral-shaped according to the average temperature cloth silk law,Places in the furnace lining puts on the silk brick, puts the silk brick to use the front part to go up 20° against falls the silk brick, the resistance wire is not easy to drop out.

由炉体、不锈钢坩锅、电动往复式摆动料架、不锈钢速冷包、电热元件和自动控温柜组成，可以使用不同溶剂，进行零件淬火、回火加热、等温淬火冷却，液体化学热处理等多种工艺，炉体由型钢和钢板焊接而成，炉面采用δ=14mm板制成，硝盐炉衬采用超轻质高强度0.6g/cm3微珠耐火砖，夹层置硅酸铝纤维，炉衬与炉壳间填充保温膨胀保温粉，整个结构为标准型节能炉衬，硝盐炉的发热元件采用较粗直径0Cr25Al5高温电阻丝绕成螺旋状按照均温布丝法，安置在炉衬的搁丝砖上，搁丝砖采用前部上翘20°防掉丝砖，电阻丝不易掉出。

This article uses the literature material law, the cut-and-try method, visits the survey procedure, the mathematical method of average and so on, in the back more -like high jump teaching, the use skill migration rule, begins from the interesting teaching to create the thin raw white silk and the design sports game, and utilizes it in the back -like high jump experiment teaching, through the teaching discovered utilizes the game teaching method in the back more -like high jump teaching, not only is advantageous to the student to complete technical movement grasping, moreover is advantageous to the change former back -like high jump teaching arid tasteless aspect, thus enhances the teaching effect.

本文采用文献资料法、实验法、走访调查法、数理统计法等，在背越式跳高教学中，利用技能迁移规律，从趣味性教学着手创编与设计体育游戏，并把它运用于背越式跳高实验教学中，通过教学发现在背越式跳高教学中运用游戏教学手段，不仅有利于学生对完整技术动作的掌握，而且有利于改变以往背越式跳高教学枯燥乏味的局面，从而提高教学效果。

In Chapter 2 of this thesis, the kinetic equation of substrate reaction in presence of denaturant has been derived. A re-examination of the effect of high concentrations of guanidine hydrochloride on the inactivation of papain, taking into consideration the effect of high concentrations of guanidine hydrochloride on the Michaelis constant, showed that, for papain, the substrate gives no protection on its inactivation.

我们在第二章中推导了变性剂存在下的底物反应动力学方程，并在考虑了高浓度盐酸胍对酶催化反应米氏常数的影响的前提下，根据推导的动力学方程重新分析了盐酸胍存在下木瓜蛋白酶的失活动力学，结果表明底物对木瓜蛋白酶的失活没有保护作用。

High-frequency and high power electronic or microwave devices, because of their excellent properties such as wide band gap, high electron saturation drift velocity, low dielectric constant, high thermal conductivity, good chemical and thermal stability, and so on.

同时由于GaN基材料具有电子漂移饱和速度高、介电常数小、导热性能好、化学和热稳定性好等特点，也非常适合于制作高温、高频及大功率电子器件。

High fever, cough more obvious symptoms of runny nose, rash Department before the buccal mucosa plaques many measles; rubella general fever is not high, little cough, ears, the occipital lymph nodes; measles exanthema high fever, 2-3 days after the fever that is, on its own;恶寒early scarlet fever, throat swelling fester, the "Yangmei" tongue-like; chickenpox generally lighter symptoms, fever is not high.

全身症状麻疹发热较高，咳嗽流涕症状较明显，出疹前颊粘膜处多有麻疹粘膜斑；风疹一般发热不高，少有咳嗽，耳后、枕部淋巴结肿大；小宝宝急疹发热较高，2—3天后即自行退热；猩红热初起恶寒发热，咽喉红肿溃烂，出现"杨梅"样舌；水痘一般症状较轻，发热不高。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。