查询词典 nucleotide

In mammalian cells, RNAi can be triggered by 21-25 nucleotide duplexes of small interfering RNA. In the postgenome era, RNAi has broad application prospect in probing gene function and drug research.

在哺乳动物细胞里，RNAi可以由21－25个核苷酸长度的小干扰RNA触发，在后基因组时代的基因功能研究和药物开发中具有广阔的应用前景。

Entrez is the integrated, text-based search and retrieval system used at NCBI for the major databases, including Nucleotide and Protein Sequences, Protein Structures, Complete Genomes, Taxonomy, and others.

本网站是一个综合性的、全文搜索系统，使用NCBI为主要数据库，包括核苷和蛋白质次序，蛋白质结构，完全基因组，分类法和其他。

Entrez is the integrated, text-based search and retrieval system used at NCBI for the major databases, including Nucleotide and Protein Sequences, Protein Structures, Complete Genomes, Taxonomy, and others.

本网站是一个综合性的，全文搜索并取回的系统，使用NCBI为主要数据库，包括核苷和蛋白质次序，蛋白质结构，完全基因组，分类法和其他。

1764 Nucleotide mutations of HBV was identified by cccDNA sequence analysis when detectable, or by PCR of HBV X gene segment spanning the mutation region. Sequence homology analysis was accomplished by using Entrez software.

其中，72例为肝细胞癌，18例为终末期肝硬化，对外科切除和穿刺标本的病理学分析表明这些人群普遍存在慢性活动性肝炎的病理背景。

Entrez is the text based search and retrieval system used at NCBI for all major databases including PubMed, Nucleotide, and Protein Sequences, Protein Structures, Complete Genomes, Taxonomy, OMIM and many others.

Entrez 是 NCBI 的搜寻和取回系统，提供使用者完整地存取序列、图谱、分类和结构等资料，并可搜寻许多连接资料库的资料。

Mechanical strains also regulated the protein and mRNA expression of several differentiation markers, as well as the activation of extracellular signal-regulated kinases, p38 MAP kinase and protein kinase B in a frequency-dependent manner. Furthermore, the inhibition of p38 pathway could block the strain-frequency induced the phenotype modulation of VSMCs, neither ERKs nor Akt. Frequency of mechanical strain, not conditioned medium, regulated the phenotype of VSMCs in a frequency-dependent manner. Rho-GDI alpha was suppressed by the mechanical strain at 1Hz.

采用免疫细胞化学法检测VSMCs形态和排列的变化；RT-PCR和Western blotting检测表型标志分子α-肌动蛋白、肌球蛋白重链(SM1/2)、肌动蛋白相关蛋白SM22α和调宁蛋白(h1-calponin)的mRNA和蛋白水平的变化；抑制剂或RNA干扰阻断可能的信号调节分子的活性或表达，包括p38、细胞外信号调节激酶1/(2extracellular signal-regulated kinases， ERK1/2)、蛋白激酶B和Rho-鸟苷酸解离抑制因子(Rho-guanine nucleotide dissociation inhibitor， Rho-GDI alpha)，研究了不同频率张应变对VSMCs表型转化的影响及其调节机制。

On the other hand, for ADRBK2 gene, although 15 novel single nucleotide variants were found in exonic and flanking intronic regions, the frequency of variants were very low, and only one rare missense variant and two silent variants were found in coding region.

对于ADRBK2基因，在外显子及外显子与内含子交接区域内共发现了15个新的变异，其中在编码区发现了一个罕见的错义变异Kps208S叫和两个同义变异。

This kind of configuration suits the multi-nucleotide chain's purine pyrimidine alternate area. in 1989, the American scientists with scanning tunnel electron microscope law visual observation double helix DNA double helix DNA ︰ in 1952, Austrian lineage US biology chemist Zha Qiefu (E.chargaff,1905-) have determined in DNA 4 kind of basic group content, the discovery gland fat ling and thymine quantity are equal, the bird fat ling and cytosine quantity is equal.

这种构型适合多核苷酸链的嘌呤嘧啶交替区。1989年，美国科学家用扫描隧道电镜法直接观察到双螺旋DNA 双螺旋DNA︰1952年，奥地利裔美国生物化学家查伽夫（E.chargaff，1905—）测定了DNA中4种碱基的含量，发现其中腺膘呤与胸腺嘧啶的数量相等，鸟膘呤与胞嘧啶的数量相等。

The nucleotides sequence and deduced amino acid sequence of these cDNA figments mentioned above were divided into two fractions. One is carbon part of L gene , the other is 5 terminal,and they were compared with other rabies-related virus strains published in NCBI previously.The result show that the homology of nucleotide sequence and amino acid sequence of carbon part in L gene among these two rabies virus strains is 91.3% and 95.8%, and these two strains belong to type of gene I.

本实验以吉林鹿源DRV8202株及河南鼠源野毒株MRV的L基因的C端为主要研究内容，用RT-PCR和3'-RACE方法对其进行了克隆和测序，将所测得的核苷酸序列和推导的氨基酸序列分成两个部分，一是L基因C端序列，另一个是L基因5'端的非编码区，并与NCBI上公开发表的狂犬病毒其它毒株的相应片段进行分析比较。

It contains 215 bp, named as ZM908. Biosoftware anlysis sug gests that ZM908 gene properly belongs to the mRNA-like non-coding RNA gene which is purposed to lack of obvious open reading frame (the longest possibly contains 98 AA), contain poly tale and have stable RNA structure in vivo. ZM908 contains high conserved nucleotide sequence with ZM401 (including 371-598bp, 698-847bp and 929-1047bp in ZM908). The highest conserved sequence reaches 86%.The RT-PCR analysis result revealed that ZM908 is transcriptable.

基因分析显示这段序列含1215bp，命名为ZM908；采用生物学软件对ZM908序列和结构进行分析，表明该基因缺乏明显的开放阅读框架，序列中最长可能的开放阅读框架仅编码98个氨基酸，具有poly尾部结构，RNA分子具有稳定的二级结构，符合非编码RNA基因的特点，可能属于类似于mRNA的非编码基因；ZM908与ZM401有高度保守的区段(ZM908序列中有三段和ZM401是高度保守的，分别为371-598bp，698-847bp和929-1047bp)，相似性最高达到86%。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。