查询词典 nucleotide

The former stimulates the cells and transfer the signals into the cells through the ligation with receptors on the cell membrane. The latter, a derivative of nucleotide, causes a cytotoxic effect to suppress thymidylate synthetase activity, and, therefore, to damnify RNA and DNA synthesis.

前者通过与细胞表面的受体结合，把胞外刺激传递到胞内，诱导免疫受体介导的信号级联放大作用，引起一系列免疫效应；后者是是小分子的核苷酸衍生物，可直接进入细胞内，通过抑制胸苷酸合成酶及损伤RNA、DNA等对基因转录和核苷酸代谢产生影响，最后产生细胞毒效应。

Reaction of 5'-O-p-methoxytrityl-thymidine with 1, 1'-carbonyl-diimidazole gave the 3'-O-carbonylimidazolide, which was condensed in high yield with 3'-O-protected thymidine to give a dithymidine carbonate. In the same way, we obtained the protected trithymidine dicarbonate. After deprotection, we obtained quantatively the trithymidine dicarbonate.By the same stratagy, we completed the synthesis of dithymidine sulfite.It was shown that allyl can be used as a good protection group for hydroxyl of ribose in the synthesis of oligonucleotides consisting in some unstable nucleotide analogues.

我们在第一部分工作的基础上，以烯丙基作为3'-OH的保护基合成了保护的三胸苷碳酸酯以及二胸苷亚硫酸酯，用我们所得的脱保护条件进行了脱保护研究，得到了三胸苷碳酸酯以及二胸苷亚硫酸酯，并研究了它们合成中的一些化学问题，结果表明：烯丙基能很好地运用于这两类寡核苷酸类似物的合成中，其脱保护条件为中性，不会影响碳酸酯键及亚硫酸酯键。

While the PNA is neither classical nucleotide nor classical protein, and can resist the discomposing of nuclease and proteinase.

肽核酸与双螺旋脱氧核糖核酸更易形成三螺旋的一个重要原因是肽核酸不带净电荷。

Methods: Influenza viruses were isolated with the means of cultured in MDCK cell and embryonated eggs. The cross hemagglutination inhibition test was used for antigenic analysis and determined nucleotide sequence of HA1 genes of the influenza A (H3N3) virus.

采用MDCK细胞培养和鸡胚培养法分离流感病毒，交叉血凝抑制法进行抗原分析，对甲3型流感病毒的HA1血凝素基因作了核苷酸序列测定。

The identification was made by means of restriction enzym eanalysis, PCR and DNA sequencing. Results: The murine entire coding cDNA of 2508bp was enamplified from spleen cells. There was 100% homogenous nucleotide sequence as compared with standard sequence (NM021297) of TLR4 from Genbank.

结果：扩增得到的小鼠TLR4基因cDNA全长2508bp，编码536个氨基酸，Blast结果分析表明，该cDNA与基因库中发表的序列(NM021297)具有100%的同源性。

Seventeen strains in 2004 were evolutionally divided into two ways,in which the homology between human GZ0401 and HPC PC4-115 was 99.97% in nucleotide sequence and 100% in amino acid sequence.

Zhao等〔1〕报告，SARS-CoV分子变异与我国2004年SARS流行时期有关，认为与SARS-CoV序列缺失和特定核苷酸序列有关。

Combinatorial chemistry is a type of synthetic strategy which systematically connects a set of"building blocks"such as amino acids, nucleotide and small organic molecules to yield a large array of diverse molecular entities described as a combinatorial library. It also refers to the process of screening the compounds with the expective activity from the library.

组合化学是将诸如氨基酸、核苷酸、有机小分子等构建单元按某种组合方式连接起来，合成出包含大量化合物的化学库，并从中筛选出具有某种物理、化学或药理活性化合物的一套合成策略和筛选方案。

The divergence time between C.amherstiae and C.pictus was at least 1.7My based on the substitution rate of nucleotide acid of cytothrome-b gene in Galliformes.

根据鸡形目细胞色素b基因核苷酸替换的速率约为每百万年0.5％～ 0.7％，推断出两种锦鸡的分化时间至少为1.7百万年。

According to the nucleotide sequences, one pair of PCR primers were designed and synthesized to detect the femalespecific fragment in gonochoristic offspring.

根据所测序列设计的一对引物经PCR检测也证实该片段为雌性特异。

Sequence similarity of gyrB sequence from twelve Gordonia type strains ranged from 79.3% to 97.2%, corresponding to 270-41 nucleotide differences while there was only 0.3-3.8% difference in 16S rRNA gene sequence similarity at the interspecies level.

本研究之结果将可利用gyrB基因作为Gordonia菌种快速鉴定之依据，若两菌株之16S rDNA序列相似度大於99.7%，gyrB基因相似度大於97.2%，则判定两菌株为相同菌种。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。