查询词典 noxa

It is a great progress in the noxa and mechanism study of osteoporosis, which the participation of hormone and cytokines in bone remodeling is researched in recent years.

其骨重建中的激素及细胞因子的参与是近年骨质疏松症病因和发病机理研究的重要进展。

Results CT had a higher accuracy for the position,noxa and qualitative diagnosis of obstructive jaundice.

结果 CT检查对梗阻性黄疸部位、病因及定性诊断准确性较高。

In summary, these data suggest that Mcl-1 plays its antiapoptotic role in apoptosis partly by binding to Puma or Noxa.

综上所述，我们的实验结果暗示了Mcl-1可以通过和Puma以及Noxa相互作用从而发挥其抗凋亡功能。

We also demonstrate that BH3-only protein Noxa is upregulated during Camptothecin-induced apoptosis, which is independent of p53. In addition, we show that PI3k/Akt signaling pathway is responsible for Noxa\'s induction.

更重要的是，用RNAi的方法将Noxa的蛋白水平抑制之后可以显著地抑制CPT诱导的细胞凋亡，暗示Noxa在CPT诱导细胞凋亡的过程中起着非常重要的作用。

Luciferase assay and CREB knock-down experiments further demonstrate that CREB is involved in the transcriptional upregulation of Noxa.

有意思的是，Mcl-1的蛋白水平也可以通过P13K／Akt信号通路而被CPT上调。

On the other hand, co-immunoprecipitation assay revealed that the DM mutant seems to have a higher affinity than the Wt protein for both Puma and Noxa.

此外由共同免疫沉淀实验中发现DM hMcl-1与Puma 和Noxa间的亲和力是比Wt hMcl-1好的。

Although the regulation of several Bcl-2 family molecules, including Puma, Noxa, Bax, and Bid, by p53 has been studied intensively, the interplay between Bad (Bcl-2 antagonist of cell death) and p53 has not yet been reported thus far.

尽管Bcl-2家族中的许多分子，例如Puma，Noxa，Bax和Bid，都可以被p53转录调控，这些已经被报道并且研究的很透彻，但是Bad与p53之间的关系至今仍没有被报道和研究。

Induction of apoptosis of gastric adenocarcinoma calls by Etoposide may be assocaited with upregulation of the BH3 only proteins of the bcl2 family, Noxa and Bim.

本研究使用依托泊苷作用胃腺癌细胞，检测BH3only蛋白的表达与细胞凋亡之间的关系，研究依托泊苷诱导胃腺癌细胞凋亡的分子机制。

More importantly, blocking CPT-induced Noxa using specific siRNA significantly reduces the apoptosis response, indicating that Noxa is an essential mediator for CPT-induced apoptosis.

通过免疫共沉淀实验，我们证明了不管有没有CPT处理的情况下Noxa都可以和Mcl-1相互作用，说明Noxa和Mcl-1之间应该存在一个平衡，从而调节细胞凋亡。

Induction of apoptosis by Etoposide was associated with upregulation of mRNAs for the BH3 only proteins Noxa, and to a lesser extent, Bim. In contrast, the expression levels of mRNAs for PUMA remained unchanged before and after treatment with Etoposide.

Noxa和PUMA主要受p53调节，细胞DNA损伤后通过p53可以上调Noxa和PUMA的表达［1］； Bim主要结合在微管动力蛋白上，受到细胞因子去除、Ca2+流出、紫外线照射、微管动摇和紫杉醇等刺激后可以转移到线粒体膜上［2］，从而发挥促凋亡活性。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。