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The relationship between molecular modification of erythromycin and NMR chemical shifts was summarized. It's noticeable that downfield of shifts of H-3 (△δ 0.2) after silylation and upfield of shifts (△δ-0.4) after methylation. No changes were observed after methylation.

分析总结了红霉素分子修饰与核磁共振化学位移变化之间的关系，并且发现大环上H-3硅烷化后由高场移至低场（△δ为0.2），甲基化后又由低场移至高场（△δ为-0.4），变化均较大；而且一旦甲基化后H-3化学位移在高场几乎不再变化。

Global warming is beginning to affect the northern Japanese region of Hokkaido, with melting drift ice being one of the more noticeable effects of climate change.

全球暖化开始影响了日本北边的北海道，越来越多的流冰正在溶化，是气候变迁对当地较明显的影响。

This study shows that heparin has noticeable effect to prevent mineral deposit and delay the development of catheter encrustation .

肝素能够阻止尿路导管表面尿盐沉积延缓导管包壳发展。

Changdong" showed a noticeable enhancive effect when it was co-administrated with other anti-tumor agents or when it was co-applied with radiotherapy. The action mechanism study showed that an apparent cytotoxic effect of "Changdong" on ten tumor strains in vitro with a quantity-effect relationship was observed. Immunity experiment showed that "Changdong" could induce proliferation of spleen lymphocyte in mice bearing tumor and could improve NK cell" s activity, whereas has no impact on IL-2" s reproduction. It was also noticed that "Changdong" could induce human liver cancer QGY" s apoptosis in vitro, and it happened mainly on G0-G1 phase.

结果："长动"对小鼠移植瘤模型和人体肿瘤裸鼠异种移植均有明显抑制作用，量效关系明显："长动"与放疗和化疗分别联合应用有明显的增效作用：作用机制研究结果：细胞毒性试验研究表明"长动"在体外对10株肿瘤细胞有明显的细胞毒性作用，量效关系明显；免疫学试验表明"长动"可以诱导荷瘤小鼠的脾淋巴细胞增殖，增强NK细胞的活性，对IL-2的产生无明显影响；"长动"在体外可明显诱导人体肝癌QGY细胞凋亡，使细胞阻滞于G0-G1期。

He was one of the most noticeable members of the Reform Club, though he seemed always to avoid attracting attention; an enigmatical personage, about whom little was known, except that he was a polished man of the world.

他是个谜一样的人物，关于他的事人们知道的少之又少，只知道他是位文雅的绅士。

E.g.- noticeable increase in severity of enzootic pneumonia in grower/finisher units when they become infected with PRRS virus

在地方性二型猪链球菌病存在的情况下，PRRS可增加脑膜炎的临床病例

The state of happiness which is free from passion, Epictetus defines it also as "freedom". It is noticeable that this kind of freedom in the sense of Epictetus is not

爱比克泰德的以精神自由为鹄的的道德哲学，作为一种乱世中的典型的哲学形态，对于身处逆境中的人，无疑还是有一定的抚慰和激励作用，具有一定的现实意义。

Like the romantic emotion, like doing the exaggerative thing, it is noticeable to like, there are ones that only like oneself to like.

喜欢浪漫的感情，喜欢做夸张的事，喜欢引人注目，还有只喜欢自己喜欢的。

It is faint, but more noticeable in person.

这是微弱的，但更引人注目的人。

Immediately noticeable, however, is that his falsetto sounds more restrained than when last heard in January.

能注意到的第一个变化是他的假声，比起在今年一月时听到的要受控制得多。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了