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Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

The results are as follows: 1 mean length and weight tend to increase while dominant length and weight groups are noted to be increasing from Oct. 2004 to Sep. 2007; 2 by using length-weight formula, calculated weight value at the same length is higher for track-data than that for background-data; 3 growth parameters of L∞, W∞ and K respectively increase from 140.5 mm, 36.5 g and 0.28 a-1 to 186.0 mm, 118.5 g and 0.36 a-1 after artificial reef deployment; 4 appreciable increases are noted in body length and weight growth rate after artificial reef deployment, and inflexion age of weight growth increases from 2.55 to 2.58 years after artificial reef deployment; 5 there is an increase in critical biomass age from 3.21 to 3.77 years after artificial reef deployment; 6 there is a decrease in total instantaneous population mortality from 1.065 to 0.75 per year after artificial reef deployment; and 7 the overall population biomass of small yellow croaker stands at 131.5 tons.

结果表明:投礁后小黄鱼的平均体长和体重均呈上升趋势,优势体长组和体重组均向高值移动;同等体长情况下由投礁后体长体重关系式估算的体重比用投礁前的体长体重关系式估算的值大;投礁后小黄鱼个体生长方程的参数 L∞、W∞、K 值分别从投礁前的140.5 mm、36.5 g和0.28 a-1增加到186.0 mm、118.5 g和0.36 a-1;投礁后体长与体重生长速度与投礁前相比有所增大,且体重生长的拐点年龄从投礁前2.55 a提高到2007年的2.58 a;小黄鱼种群生物量增长的临界年龄从投礁前的3.21 a提高到3.77 a;小黄鱼种群的总瞬时死亡率从投礁前的1.065 a-1减小到0.75 a-1;鱼礁区小黄鱼资源量约

When comparing USFA concentration, it tended to be higher in female. Breast meat contained significantly higher saturated fatty acid (P.001) and leaf fat contained significantly higher USFA (P.001). C18:2 content from birds kept in wet pad type housing increased significantly between 10-11-wk old; at 10-12-wk old, the increment in male was significant while gradient increment was noted in female between 11-12-wk old. The content of USFA in breast meat tended to increase gradually with age and vice versa for SFA after 12-wk old. The trend for SFA and USFA content in thigh meat were gradual after 7-wk old while no considerable change was noted for the SFA and USFA content in the leaf fat.

胸肉含有显著较高之总饱和脂肪酸(P.001),腹脂含有显著较高之USFA(P.001)。C18:2含量在水帘式畜舍在10到11周龄之间有一明显的增加,开放式畜舍则在11到12周龄之间有一明显的增加;公鸡部分在10到12周龄之间有一明显的增加,母鸡部分则在11到12周龄之间有逐渐增加之趋势;不同部位的部分则可以发现,胸肉中USFA含量,会随著周龄的增加而有逐渐增加的趋势,SFA则反之,且皆在12周龄以后趋於平缓,腿肉中之SFA及USFA含量,皆在7周龄以后趋於平缓,腹脂中之SFA及USFA含量,在全期则变化不大。

At ER, septic shock status was noted and leukocytosis was also noted.

在急诊室

Towards the end of the discussion, Dorsey said that Twitter is just a tool and that it can't change any governments itself, but that it is the users who can use it to change governments.As MacManus noted during the discussion, it is people like Ai Weiwei that are using these tools effectively. One day, Ai Weiwei noted towards the end of the discussion, we won't need tools like Twitter to change our governments anymore.

在谈话的结尾,dorsey说,twitter本身只是一个工具,不可能去改变和影响政府;但是twitter的使用者,却可以利用它去改变统治者和政府。macmanus称是像艾未未这样的人让twitter发挥了真正的作用;而艾未未说,有一天,我们会不必要再用像twitter这样的东西去改变政府。

RESULTS: Among these patients, 75 (75%) had a variability of ± less than 2 times per day in voiding frequency within the 3 days. Twenty-four patients (24%) had nocturnal polyuria, increased bladder sensation was noted in 36 patients, and overactive bladder was noted in 56 patients.

结果:所有的病人中有75位(75%)在三日排尿日志中排尿次数的变异性为±2次以下, 24 位病人具夜间多尿症,36位具膀胱超敏感性,56位则诊断具有膀胱过动症。

Here we present a case of 21 year-old male who suffered from recurrent swelling in left side of mandible which had received surgery for ossifying fibroma in another hospital when he was 19 years old. Obvious facial asymmetry was noted but no sensory dysfunctions were detected. The lesion showed well-demarcated, multilocular radiolucency but radiopacity centrally. We applied segmental resection via extra-oral approach and reconstructed with anterior iliac crest bone graft. After removal of MMF in six week, the wound healed well and joint function was good without malocclusion. After follow-up of one year, no recurrences were noted.

本病例为-21岁之男性,在19岁时因为左下颚骨角区肿大在某医院接受外科手术处理,术后病理报告为骨化纤维瘤,因为复发的肿胀而来本院寻求治疗,临床检查并无疼痛及下唇区感觉异常的问题,放射线影像为周界清晰,多腔室放射透过性合并中央放射不透过性之不规则小块,手术方式为从口外颚下切线,做下颚骨片段式切除,并以肠骨脊海绵骨移植修补骨缺损加以颚间固定六周,术后伤口恢复及愈合良好,颚骨关系稳定无咬合异常的情况,无张口受限的问题。

After analysis using the Wilcoxon matched paired signed rank test, significant differences were noted. Findings and suggestions include the following: The rise in Mini- Mental State Examination and reduction in depression scale scores, although noted, were not significant, and the self-achievement, emotional stability, family atmosphere, and physical needs of participants were met.

研究发现及建议说明如下:受服务者简易智能状态测验(Mini Mental State Examination, MMSE)量表分数有提升,忧郁症量表有降低的现象但未达显著性水准;受服务者在团体中对自我成就感、情感稳定情形、家庭式气氛与生理需求能获得显著满足。

Recent visual impairment was noted in 11 of the 15 eyes studied, and metamorphopsia was noted in eight eyes. Four eyes were asymptomatic.

在被研究的15只眼中,11只眼有最近的视力损害,8只眼具有视物变形症。4只眼无症状。

A prominent visible blood vessel in the pontocerebellar angle was noted in the affective side, but no similar finding was noted in the non-affective side. In conclusion, acupuncture may improve facial spasm, this effect of acupuncture probable mediates via a antidromic impulse of facial nerve to decrease intensity of impulse that is orthodromic transmission from facial motor nucleus or from focal demyelization of neurovascular compression; acupuncture evoked cerebral cortex to produce a descending inhibiting impulse to inhibit the hyperexcitablity of facial motor nucleus to improve facial spasm.

结论是针刺可以改善颜面肌痉挛,针刺可能经由诱发颜面神经逆行的神经冲动减少颜面运动核或神经血管压迫之focal demyelination处往下而来神经冲动的强度;或者针刺诱发大脑皮质产生抑制性下行神经冲动抑制颜面运动核的过度兴奋来改善颜面肌痉挛。

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