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Results the mmse score of the case 1 was 19, which was lower than normal. the wis score of the case 2 was normal. the pet of 2 patients showed that there were many hypo-metablism areas in cortex or subcortex.in addition,some cortical hypo-metablism areas of pet were not correspondingly found lesions in cortex or subcortex by mri.

结果 例1简易精神状态检查量表评分19分,低于正常;例2韦氏智商测试为正常水平。pet影像检查显示2例患者存在多处皮质、皮质下代谢减低区;mri中未发现相应皮质或皮质下白质病灶。

Experimental results show that, compared with the normal pulse, the wiry pulse has an increased PWV(P<0.01 or P<0.05), the thready pulse has a decreased PWV(P<0.05),but the PWV of the smooth pulse is not significantly different from the normal's (P>0.05). PWV highly correlates with the artery blood pressure.

实验测定的结果表明,弦脉的脉搏波速度比同龄组平脉有显著性增大(P<0.01或P<0.05),细脉的脉搏波速度比同龄组平脉有所减小(P<0.05),而滑脉与同龄组的平脉相比无显著性差异(P>0.05);脉搏波速度与动脉血压之间具有很大的相关性。

The observation showed that sterile plants and fertile plants in the pollen mother cell stage is not very different, when microspore mother cells of male sterile plants enter meiosis period, it could form normal tetrad cell , tetrad cell is normal in early development stage, In the uninucleate microspore stage , tapetal cells were vacuolization, the microspores were extruded to the middle by tapetal cells.

本研究利用石蜡切片法,结合光学显微镜技术对樱桃萝卜核质互作雄性不育系的不育株和对应保持系可育株的花药发育过程进行细胞形态学观察,观察结果表明:不育株与可育株在花粉母细胞时期差别不大,不育株的花药小孢子母细胞进入减数分裂期后,可以正常的形成四分体,四分体前期发育正常,而在单核小孢子期绒毡层细胞出现液泡化,绒毡层细胞向中间挤压小孢子。

The result of uroscopy of the proband was strong positive. There was a novel deletion mutation of c.876-877 del TC in the coding region of exon 6 of IDS gene, which was a hemizygous mutation. However, the mutation of his mother and sister was a heterozygous mutation. Detection of the exon 6 of IDS gene showed that the mutation was not found among normal controls and other patients with MPS I, IV, and VI other than MPS II. Homology comparison of amino acid sequences from different species showed that the phenylalanine glutamine of the mutation site of c.876-877 del TC located in p.292-293 was highly conserved. The activity of IDS enzyme of the proband was only 2.3 nmol/4 h/mL, which was much lower than normal; but the activity of IDS enzyme of his father, mother and sister was 641.9 nmol/4 h/mL, 95.8 nmol/4h/mL and 103.2 nmol/4h/mL, respectively.

结果显示:先证者尿检呈强阳性;其IDS基因exon 6编码区内存在c.876-877 del TC新缺失突变,为半合子突变,而其母、其姐为杂合突变;正常对照和其他非II型MPS患者的IDS基因exon 6的检测结果均未发现该突变;不同物种氨基酸序列的同源性比对显示: c.876-877 del TC突变所在的位置即p.292-293的苯丙氨酸谷氨酰胺高度保守;酶活性测定的结果显示:先证者的IDS酶活性仅为2.3 nmol/4 h/mL,大大低于正常值,而其父的为641.9 nmol/4 h/mL,其母的血浆酶活性为95.8 nmol/ 4h/mL,其姐的为103.2 nmol/4 h/mL。

There is still no consensus on the expression of the two isoforms in the human prostate and their cellular locations are also controversial. It is not known to which extent each of these isozymes contributes to overall enzyme activity in different prostatic tissues. In an attempt to elucidate which isoform of the 5α-reductases is responsible for the metabolism of T in normal and diseased human prostate, we performed qualitative and semi-quantitative studies of both enzymes in normal, benign hyperplastic and adenocarcinomatous human prostate tissues by RT-PCR and Immunohistochemistry methods.

现已成功地克隆出编码Ⅰ型及Ⅱ型5α-还原酶的基因,关于这两型5α-还原酶在前列腺组织及不同类型细胞中的存在、分布情况及其对组织中睾酮代谢各自所起的作用仍存在许多争议,为此我们应用RT-PCR及免疫组化方法对国人正常、良性增生以及前列腺癌组织中两型5α-还原酶的表达进行了定性和半定量研究。

Results: 1. The depression patients in neuroendocrine abnormity make up 59.4% of the total. 2. Correlation of clinical features and neuroendocrine diversity of depression patients.① Agitate symptom often existed in HPA axle abnormal group.② The weight diversity was not obvious suffered HPT axle abnormal depression frequently, Sleep disorder and anxiety often exist in HPT axle abnormal group.③ Elder women suffered HPG axle abnormal depression frequently, The symptom of somatic often exist in HPG axle abnormal group.④ Self-reproach and delay symptom often existed in the HPA axle and HPT axle abnormal group.⑤ The adolescent fuffered the normal neuroendocrine group, Patients of the normal neuroendocrine group were often combined with anhedonia.

结果显示:⒈抑郁症患者神经内分泌异常率达到 59.4%;⒉抑郁症患者临床特征与不同神经内分泌轴具有相关性以下几点值得注意;① HPA 轴异常组抑郁症患者多伴有激越症状;② HPT 轴异常组抑郁症患者体重改变不明显,多伴有睡眠障碍、迟纯症状和焦虑症状,常出现自杀观念;③ HPG 轴异常组抑郁症患者多发于年龄偏大的女性,躯体症状多明显;④ HPA 轴和 HPT 轴均异常组抑郁症患者多伴有体重减轻和明显自责和迟滞症状;⑤正常组抑郁症患者多发于青少年,快感缺失症状明显。

Blood pressure should be reduced to normal level to prevent heart and cerebral vessels to occur arteriolosclerosiswhen the blood pressure of hypertensive patient is not very highor the duration of illness is short. when blood pressure rises very high or the course of disease is long, blood pressure should be lowered to slightly higher than normal blood pressure level, so it can prevent arteriolosclerosis to be deteriorated further and can prevent the occurence of cerebral ischemia and infarction.

在血压升高幅度不大或起病不久的高血压患者,治疗时应将血压降至正常水平,以预防心脑血管发生动脉硬化;在血压升高幅度大或病程长者,治疗时应将血压降至比正常血压稍高的水平,即要防止动脉硬化进一步加重,也要预防脑缺血和脑梗塞的发生。

Do not worry too much about it, and now most well-nourished mothers, pregnancy late baby is growing rapidly, and large number of normal babies, I HUAI郭郭when the 37 weeks when the biparietal diameter 9.7CM, Oh, 39 weeks maternity leave, birth 8 jin The children are healthy normal.

不用过分担心,现在的母亲大多营养良好,妊娠后期宝宝增长快,宝宝大一些很正常的,我怀郭郭的时候,37周时双顶径9.7CM,呵呵,39周分娩,出生时8斤,孩子很健康很正常的。

Based on the Arcview platform and compiling programs by ourselves, the DLPM of urban area of Jinan in 1998 and 2001 is established. The main conclusions are: 1 general trend of land price is reduction from central base point to urban edge, but there are different characteristics in different direction; 2 from one edge to another, land price shows low-high-low, and its sections through urban areas show normal school and deflection normal school; 3 land price evolutes with time, concaveness land price terrace changes little or gentle or protruding, and protuberant land price terrace changes little or not, price terrace or big or gentle; 4 the increasing potential of price is analyzed by the increasing rate and increasing speed of land price.

分析数字地价模型得出结论:①地价从中心基点向城市边缘总趋势是降低,但不同方向表现出不同的特点;②在贯穿市区的地价剖面中,一般表现为从一个边缘到另一个边缘的地价由低到高再到低的变化规律,由於地价剖面经过不同的市区区位,呈现出正态和偏正态的分布特点;③在时间演化上,凹性地价阶地变小或变平缓,凹性地价阶地转变为凸性地价阶地,凸性地价阶地变小或转化为非地价阶地,凸性地价阶地变大或平缓;④利用地价增值率和地价增值速度分析了地价的增值潜力。

Results: CK18 was not detected in normal and abnormal oral tissue sections. But in normal nonkeratinized mucosa, CK19 was detected in the basal cell layer dispersively. In epithelial dysplasia, CK19 was detected in the suprabasal cell layer and the number of CK19-positive cell layers was correlated with the dysplasia degree of epithelia. Furthermore, CK19 was detected in oral squamous cell carcinoma, especially in the poor-differentiated cancer cells.

结果:正常和异常的口腔粘膜均未检测到CK18;CK19可表达于正常非角化上皮的基底层细胞、异常增生上皮的基底上层细胞及口腔鳞状细胞癌中,阳性细胞数与上皮的异常增生程度及鳞癌的分化程度相关。

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