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Children under 18 years ago, the impact of children's epiphyseal height and backbone have not yet healed, and is a normal developmental stage, should not have increased the use of drugs, because in the normal period of use will affect the normal development.

孩子在18岁前,影响孩子身高的骨骺还没有和骨干愈合,是正常的发育期,切忌使用增高的药物,因为在正常期使用反而会影响正常发育。

Animals were in normal control group,6animals were in normal treated group (tPNS200mg/kg) The others were cauterized three episcleral vessels and were divided as experimental groups: groupA (50mg/kg), groupB(100mg/kg), groupC(150mg/kg), groupD (200mg/kg)and group treated by normal saline.Rat were sacrificed on schedule.

健康SD大鼠42只,其中6只为正常对照组,6只为正常用药组(三七总皂苷200mg/kg),其余30只采Akira法,烙闭大鼠右眼上巩膜静脉,制作大鼠持续性高眼压模型,随机分为生理盐水组,量效关系组分别予tPNS 50mg/kg,100mg/kg,150mg/kg,200mg/kg进行治疗一个月。

The changes were observed and anlysised. Results In the normal days and after operation, the far distance binocular vision and near distance stereoacuity were no significant difference between 14 cyclic esotropia cases and normal. In 16 cases of consecutive esotropia, 12 cases had no binocular vision before operation, and after operation, simultaneous perception were acquired in 16 cases (100%), fusional power in l6 cases (100%) while the range of fusion was lower than normal, far distance stereoscopic vision in 10 cases (62.5%), near distance stereoscopic vision in 8 cases (50%).

观察术前、术后的远双眼视觉,近立体视锐度变化:结果 14例周期性内斜视患者术前正位日及术后远双眼视觉及近立体视锐度与正常人群相比无显著性差异。16例恒定性内斜视术前12例(75%)无双眼视觉,术后16例(100%)具有同时知觉能力,16例(100%)可获得融合力,但融合范围低于正常人群。10例(62.5%)获远立体视,8例(50%)获得不同程度近立体视。

The biomechanical tests showed that two kinds of artificial bones had not significant difference on compressive strength and Young\'s modulus(P>0.05),while the flexural strength of nano-nacre artificial bone was less than the control group(P<0.05).3.The results of CCK-8 showed that the difference were not significant in each group,the proliferation of osteoblast reached the peak at the 5th day;7 days after being co-cultured,the total protein content of study group was higher than control group and blank group(P<0.05),while the difference between control group and blank group was not significantP>0.05The difference of alkaline phosphatase activities among three groups was not significant(P>0.05The SEM view showed that osteoblast attached and grew well in two kinds of artificial bone.4.X-ray photography showed that two kinds of powder started to degrade in 2 weeks;this phenomenon became more appear in 4 weeks,nano-nacre powder degraded faster than micron-nacre powder,while the hole shadow was easy to be found;in 8 weeks,all the femoral holes recovered and returned to normal bone mineral density in all groups.Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone grew fastest around the bone defect area in study group,while most slowly in blank groupP<0.05 SEM(scanning electron microscope observation showed that nano-nacre powder degraded more quickly.The same result can be found through the demineralized sections morphometric analysis,and both of the composite artificial bones made from those two kinds of nacre powder had the good connection with the adjacent tissue in rats body without apparent inflammatory response.5.X-ray photography showed that rabbit\'s bone defects healed faster in study group since NNAB implanted than in control group since MNAB implanted.At 24 weeks after operation,bone density in radial defects had nearly accessed to the normal area,while lower in control group,and turned up nonunion in blank group;The checking of BMD showed that results in study group were higher than those in control group at 8,16 and 24 week(P<0.05), and the difference between the BMD values in study group at 24 week and those in blank group was not significant(P>0.05).The gross specimens showed satisfactory histocompatibility both in study group and in control group,with bone tissue growing from two sides into the center of implanted materials; Normal slices in HE stain and hard tissue grinding slices in Stevenel\'s blue/Van Geison\'s picro-fuchsin stain showed that the bone growth tendency was better in study group than that in control group,and the medullary cavity had been penetrated to the implanted materials in study group at 24 week;Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone in both groups grew fastest 8 weeks after surgery,while slow down at 16 week.

纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨分别与成骨细胞共培养后,其各时间点CCK-8法检测值与空白对照无显著差异(P>0.05),成骨细胞均在第5天达到增殖高峰期;培养7天后,实验组细胞蛋白含量高于对照组及空白组(P<0.05),后两者之间则无显著差异P>0.05碱性磷酸酶活性在三组间均无显著差异(P>0.05电镜下可见成骨细胞在两种人工骨上都有良好生长贴附能力。4.X-ray显示两种粉体在大鼠股骨骨洞植入第2周时都开始出现了降解,第4周时更为明显,纳米珍珠层粉较之微米珍珠层粉降解更快,而空白对照组骨洞阴影仍可见,至8周时,则所有组骨洞均己闭合修复,X-ray下已不可见原钻孔痕迹,恢复正常骨质密度;硬组织磨片四环素荧光双标记结果显示纳米珍珠层粉植入组较其余两组在骨缺损区周围新骨生长速度更快,空白组速度最慢P<0.05电镜观察及常规脱钙切片亦可见到纳米粉体降解较快;由以上两种原材料制得的纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨在大鼠体内均与周围组织结合良好,无明显炎症反应。5.X-ray显示纳米珍珠层/消旋聚乳酸复合人工骨植入兔桡骨缺损区后其骨愈合速度较对照组微米珍珠层/消旋聚乳酸复合人工骨植入的快,至植入术后24周,实验组骨缺损区接近正常骨密度,对照组骨缺损区密度较低,空白组则呈现骨不连状态;骨密度测量结果显示术后8周、16周、24周实验组的骨密度值高于对照组(P<0.05,24周实验组的骨密度值与术前所测得的正常值无显著性差异P>0.05动物取材大体所见均显示组织相容性良好,骨组织逐渐由植入材料两端向中央生长;常规切片HE染色及硬组织磨片Stevenel\'s blue/Van Geison\'s picro-fuchsin联合染色均可见实验组骨缺损区长势优于对照组,至术后24周,实验组骨髓腔与材料已呈相交通状;硬组织磨片荧光显微镜下观察,两组材料在术后8周处于骨生长最快速时期,16周时速度开始减慢,术后4、8、16周时实验组的新骨生长速度均较对照组的快

Grouping lesional and homeochronous normal hip to pair, dynamic measuring AI and AI in each age groups of lesional and normal hip on before reduction、after reduction 3rd month、6th month、9th month、12th month, describing the characteristics of acetabular development in each age groups on every observation time-points, comparing the difference of lesional acetabular development with normal acetabular physiological development.

并以患侧髋关节与同期健侧髋关节进行配对分组,动态测量各年龄组患儿患、健侧髋关节在复位前、复位后第3、6、9和12个月时的髋臼指数和髋臼深度与宽度比值AI(D/W,描述各年龄组在各时间观察点上髋臼发育的特点,比较患侧髋臼发育与健侧髋臼生理发育的差异。

Methods:①Make clinical scale of the magnitude of the tongue and the palate to the group of the OSAHS and the normal control②Successive scanning of the upper airway at the states of the normal inspiration and under the Müller action on both normal controls and the OSAHS patients with multi-slice spiral computed tomography. The scope of scanning was from the roof of nasopharynx to the level of hypohyal, bonding multiplate volume reconstruction,using the image workstation to survey the cross section area, sagittal diameter, coronal diameter on the soft tissue thickness in the lateral pharyngealwall and posterior wall of the pharynx, and the postzone of soft palate, uvula palatine ,tongue and epiglottis.

采用高分辨率多排CT(multi-slice spiral computed tomography,MSCT)对正常人和OSAHS患者的上呼吸道分别在平静吸气状态下以及Müller动作下进行连续扫描,扫描范围从鼻咽顶部至舌骨下缘,图象进行三维重建,应用图像工作站测量正常人和OSAHS患者的软腭后区(retropalatal region,RP)、悬雍垂后区(uvula region,UV)、舌后区(retroglossal region,RG)和会厌后区(epiglottal region,EPG)气道横截面积(cross section area,CSA)、矢状径、冠状径、咽侧壁和咽后壁软组织厚度以及舌体大小(包括舌体长度、舌体最宽处的宽度、中纵切面面积,舌背高度)。

In the paper only the range of normal value and the description of frequency distribution are discussed. In theory the widely-used percentile method to determine the range of normal value is imperfected. Curve fitting method show some advantage in determining the range of normal value, but is difficult to calculate.

从理论上说明了现在常用的确定正常值范围的方法存在一定的问题,尤其证明了大家使用得比较多的百分位数法存在的缺陷,说明了曲线拟合法的优点,而在频数分布拟合完成之后,就已经找到了频数分布资料的理论分布曲线,有了理论分布函数,我们利用分布函数计算正常值范围就比较容易,也比较准确。

Methods Rabbits were randomized to three groups. Complex model group were fed with feed containing 0.5% cholesterol for 3 weeks. At the fourth, eighth and twelfth weeks, rabbits were given injection of lipopolysaccharide (1 μg) at auricular artery, cervical part and fold inguen, respectively. Normal group were fed with normal diet, while High cholesterol group were fed with feed confaining 0.5% cholesterol only. After 16 weeks, vascular tissues were analyzed using morphometric and histological methods, and the sera were checked for cholesterol, LDL-C, C-reaction protein and tumor necrosis factor-α. Results The cholesterol and LDL-C of High cholesterol group were increased, compared to those of normal group.

给含0.5%胆固醇的饲料,3周后,分别在第4、8、12周采用耳动脉内、颈部、腹股沟处肌肉注射大肠埃希菌脂多糖,并设立正常组和单纯高脂组。16周后观察兔的一般状态,取血清检查血脂六项、C-反应蛋白和TNF-α,取耳动脉、颈动脉、主动脉弓、胸主动脉、腹主动脉、髂动脉、肝脏,放置4%多聚甲醛中过夜,常规行HE染色,检查血管病变和相关脏器病变情况。

Based on this,We designed a series of experiments to study the treatment and its mechanism of Iridoids composition of Valeriana jatamansi Jones of the IBS animal model.1 Research on Iridoids composition of Valeriana jatamansi Jones in the role of gastrointestinal function.1.1 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of normal miceMethods:Compared with normal group and YJBH group,mice which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 4 days drug given.Results:Compared with normal group,gastric emptying and small intestinal propulsion in 35.6mg/kg and 17.8mg/kg group was inhibited.

课题通过观察蜘蛛香环烯醚萜对正常及IBS模型动物的胃肠道功能、精神活动的影响,以及蜘蛛香环烯醚萜干预下IBS大鼠结肠、血清、中枢5-HT含量,结肠5-HTR3A受体的mRNA和色氨酸羟化酶(TPH1)的mRNA表达,结肠和血浆中SP和VIP含量以及结肠中肥大细胞分布,探讨蜘蛛香环烯醚萜对腹泻型IBS的治疗作用及其作用机理,为临床治疗IBS提供实验依据。1蜘蛛香环烯醚萜对胃肠功能的作用目的:探讨蜘蛛香环烯醚萜对胃肠功能的影响1.1蜘蛛香环烯醚萜对正常小鼠胃肠功能的作用方法:正常小鼠灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组和越鞠保和丸组对照,给药4日后测定动物的胃排空率和小肠推进率。

Then the index of ulcer was measured and the ulcer inhibitory rate was measured.Results: The weight of ear of mice treated with XSG was reduced compared with that of normal group,and the joint swelling of rat was less than that of normal group. The latence of sole-ache caused by hot-plate and bellyache caused by acetic were both delayed and the times of skewing body within 15 minute were reduced compared with that of the normal group.

结果:香砂六君颗粒对小鼠二甲苯性耳廓肿有明显对抗作用;对大鼠蛋清性关节肿有一定对抗作用;对热板和醋酸所致小鼠疼痛香砂六君颗粒能明显延长其舔足潜伏期和减少扭体次数;对大鼠利血平型及乙酸型胃溃疡香砂六君颗粒组的溃疡指数从模型组的46.26±1.64mm2和23.02±2.05mm2减少为34.75±0.82mm2和13.84±1.2mm2;对大鼠利血平型及乙酸型胃溃疡香砂六君颗粒的溃疡抑制率分别为51.43%和39.87%。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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