查询词典 non-localized

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析，并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、吲哚青绿血管造影(indocyanine green angiography，ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例，73.5%)，双眼同时患病118例(80.8%)；后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%)；前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例，98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%)；后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障；毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现；炎症活动期FFA典型表现为斑驳状高荧光，ICGA发现脉络膜血管扩张、通透性增高等改变；VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎，随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

SMART analysis suggested that the ORF encoding protein contained a Ldh_1_N and a Ldh_1_C domain. Psite analysis showed that there was lactate dehydrogenate active site in the protein, which localized in cytoplasm according to PSORT program analysis.

SMART分析表明ORF编码的蛋白质具有Ldh_1_Ndomatn和Ldh_1_Cdomain，Psite分析表明有L-乳酸脱氢酶活性位点，PSORT程序分析将其定位于细胞质中。

This behavior is suggested to be originated from delocalization of the localized carriers by thermal activation.

由变温光激萤光光谱，观察到随温度增加能量峰值有下降、上升再下降的现象，此S型行为是因为载子受到温度的活化，脱离原本的局域态而跃迁到高能量能态。

A method is proposed to construct a localized active functional space from the density matrix of a large system.

报道了从大体系的密度矩阵出发构造定域于指定局部的活性泛函空间的方法和程序。2。

Absolute permeability at any given location may change in response to localized changes in stress within the rock pore system owing to depressurization during production.

在任何位置的绝对渗透率，由于生产过程中的减压，可能会随着岩石孔隙系统中应力的局部变化而变化。

Chill blocks are also used at points where it is designable to have localized hardening, as in the case of bearings or wear surfaces.

冷块也用于站后，这是设计性，以有局部硬化，在案件或轴承磨损表面。

The results showed that localized anodic dissolution is the essential cause of SCC, while considerable dezincification enhanced the suseptibility to cracking.

结果说明，包含铜在内的局部阳极溶解是该体系SCC的根本原因，而大量的脱锌则加剧了开裂敏感性。

In addition to glial cells, CNTF immunoreactivity are widely localized at neurons in the olfactory bulb, cortex, hippocampus, cerebellum, diencephalon and brainstem.

结果表明，CNTF免疫反应物质除广泛存在于中枢神经系统的胶质细胞外，亦有神经元的广泛染色，而且分布广泛，在嗅脑、大脑皮层、海马、小脑、间脑、脑干中均有明显的染色。

In Chapter 2, we firstly examine the propagation direction of travelling target waves induced by the localized inhomogeneity.

在第2章中，我们首先研究振荡系统中缺陷对靶波传播方向的选择。

We observed that a majority of dsRNA was localized in the nuclear periphery discontinuously after 24 hours of transfection. Time course showed that the labeled dsRNAs were maintained in cultured silkworm cells for up to 5 days. After six days, the signal was too weak to be detected.

用荧光显微镜观察FAM标记的dsRNA在细胞内的定位，发现在转染24小时后，dsRNA开始越来越多的聚集在细胞核的周围，并呈不连续分布，细胞内的荧光强度也越来越强。dsRNA在家蚕细胞中可以维持5天的时间，但到第6天时细胞内已检测不出荧光信号。

Diabetes is a social disease that affects several million people worldwide.

糖尿病是一个社会性疾病，全世界有数百万人罹患此病。

I'll call you on Friday to see if we can reschedule our luncheon meeting at your convenience.

我星期五会给您打电话在您方便的时候我们重新安排我们的午餐约会。