查询词典 neurotoxin

Results from whole-cell patch clamp showed: 1 BmK Ⅰ(α-like neurotoxin) was found to prolong the duration of action potential and promote the amplitude of action potential. The effects could be attributed to the selective action of BmK Ⅰ on the TTX-S Na〓 channel: slowing the inactivation process of Na〓 channel, increasing the amplitude of peak Na〓 currents; 2 BmK abT, a new-type neurotoxin with higher sequence homology to β-type scorpion neurotoxin, was found to slow the inactivation process of Na〓 channel and prolong the duration of action potential in DRG neurons.

全细胞膜片钳研究发现：1）类α型哺乳动物毒素BmK Ⅰ可延长部分DRG神经元全细胞动作电位的时程，增加动作电位的幅度，这些效应可归咎于BmK Ⅰ选择性地作用于DRG神经元TTX—S钠通道，延缓TTX—S钠电流的失活化相，峰钠电流幅度增加；2）BmK abT，一个与β型毒素同源性较高的新型蝎毒素可抑制DRG神经元全细胞钠电流失活化过程，使动作电位时程增加。

The effects could be attributed to the selective action of BmK Ⅰ on the TTX-S Na〓 channel: slowing the inactivation process of Na〓 channel, increasing the amplitude of peak Na〓 currents; 2 BmK abT, a new-type neurotoxin with higher sequence homology to β-type scorpion neurotoxin, was found to slow the inactivation process of Na〓 channel and prolong the duration of action potential in DRG neurons.

这些结果提示BmK IT2和BmK AS-1的外周抗伤害性效应可能是通过它们对小直径DRG神经元外周游离末梢即C纤维末梢上的TTX-S和TTX-R钠通道的门控调节所致，且BmK IT2对角叉菜胶致炎大鼠较强的抗伤害性作用可能是由于它对TTX-R钠通道较高的敏感性所致。二。特异性钠通道调制剂-东亚钳蝎神经毒素的电生理特征。

If diagnosed early, food-borne and wound botulism can be treated with an antitoxin that blocks the action of neurotoxin circulating in the blood.

如果早期诊断，经由食物传染的伤口可以治疗肉毒中毒的抗毒素阻挡的行动，神经循环血液中。

Huwentoxin-XVIIb1 (HWTX-XVIIb1) is a novel peptide neurotoxin, isolated and purified from the Chinese bird spider Selenocosmia huwena Wang. It contains 31 amino acid residues including 8 cysteines.

虎纹捕鸟蛛毒素-XVIIb1 (HWTX-XVIIb1)是从虎纹捕鸟蛛粗毒中提取、表达、分离纯化的一种新型多肽，它由31个氨基酸残基组成，含8个半胱氨酸。

Huwentoxin-Ⅱ is a neurotoxin purified from the venom of the Chinese bird hunting spider Selenocosmia huwena, which contains 37 amino acid residues including 6 cysteine forming three pairs of disulfide.

虎纹捕鸟蛛毒素Ⅱ（huwentoxin-Ⅱ，HWTX-Ⅱ）是从虎纹捕鸟蛛Selenocosmiahuwena毒液中纯化出的新型多肽神经毒素，含有37个氨基酸残基，包括6个半胱氨酸，形成了三对二硫键。

Abstract］ Objective: To analyze botulinum neurotoxin type E heavy chain antigen epitopes and its spatial structure.

目的：分析肉毒毒素E型重链的抗原表位及空间结构。

By sequencing randomly-selected clones from the library and usingbioinformatics, 73 novel expressed sequence tags were obtained, in which therewere 24 full-length cDNAs, including cytolysin gene, neurotoxin genes, and greenfluorescence gene. Functional study on these novel genes is an ongoing task in ourlaboratory.

对文库克隆进行序列测定和生物信息学分析，已经获得了73个海葵新表达序列标签，有24个全长cDNA，其中包括海葵细胞毒素、海葵神经毒素、绿色荧光蛋白等具有开发应用价值的新基因。

The venom of elapid snakes contains a number of small proteins that display a broad spectrum of pharmacological activities.In study on the neurotoxin from the venom gland of Bungarus multicinctus,five cDNA sequences (MNCTL1-a,MNCTL1-b,MNCTL1-c,MNCTL1-d and MNCTL2) encoding two novel proteins were obtained from the total RNA by reverse transcription-polymerase chain reaction.

采用SMART技术和RT-PCR方法，从同一个银环蛇毒腺中克隆到了5 种尚未报道过的心脏毒素类似物全长cDNA序列（MNCTL1-a、MNCTL1-b、MNCTL1-c、MNCTL1-d和MNCTL2）。5种序列中，MNCTL1-b、MNCTL1-c、MNCTL1-d和MNCTL2的长度均为505 bp，包括5′非翻译区32 bp，3′非翻译区212 bp和其余261 bp组成的一个完整开放阅读框；MNCTL1-a 由于3′非翻译区24 bp的缺失，全长cDNA仅为481 bp。

Agkistrodotoxin, a presynaptic neurotoxin and one of the two neurotoxins from the snake venom of Agkistrodon halys Pallas, has been further purified by DEAF -cellulose and CM-Sephadex column chromatography and vertical slab polyacrylamide gel electrophoresis.

本文在前文的基础上，改进了蝮蛇神经毒素的分离方法，纯化了蝮蛇毒中的两个神经毒素之一，突触前神经毒素Agkistrodotoxin，并对其生化特性进行了分析。

Lindane is another type of insecticide although it is a lot stronger than other insecticides and has neurotoxin chemicals so it needs to be used carefully.

林丹是另一种类型的杀虫剂，虽然这是很多比其他杀虫剂，并已神经毒素的化学品，因此需要加以审慎使用。

Methods Clinical data of 3 cases of bile duct injury during laparoscopic cholecystectomy were analyzed retrospectively.

回顾总结3例LC术中胆管损伤的临床资料，分析3例胆管损伤的原因及对策。

These techniques are applied to the gobang.

本文将这些技术用于五子棋中。